2023 - Research.com Biology and Biochemistry in China Leader Award
2022 - Research.com Biology and Biochemistry in China Leader Award
His primary scientific interests are in Biochemistry, Cell biology, Apoptosis, Caspase and Protein structure. He regularly links together related areas like Biophysics in his Biochemistry studies. His biological study spans a wide range of topics, including Caenorhabditis elegans and APAF1.
His research investigates the link between Apoptosis and topics such as Mitochondrion that cross with problems in ENDOG, Endonuclease, RNA interference, Cytosol and Tissue homeostasis. His studies deal with areas such as Inhibitor of apoptosis and Enzyme activator as well as Caspase. The various areas that he examines in his Protein structure study include Ryanodine receptor, Antiporter, Cryo-electron microscopy, DNA-binding protein and Peptide sequence.
His primary areas of investigation include Cell biology, Biochemistry, Caspase, Biophysics and Protein structure. His research integrates issues of Apoptosome, Apoptosis, Programmed cell death and RNA splicing, Spliceosome in his study of Cell biology. Within one scientific family, Yigong Shi focuses on topics pertaining to Stereochemistry under RNA splicing, and may sometimes address concerns connected to Active site.
The concepts of his Caspase study are interwoven with issues in Structural biology, Enzyme activator, Plasma protein binding and Effector. His Biophysics research focuses on Transmembrane domain and how it connects with Membrane protein. His studies in Protein structure integrate themes in fields like Peptide sequence and Binding site.
Yigong Shi spends much of his time researching RNA splicing, Spliceosome, Cell biology, Small nuclear RNA and Biophysics. His RNA splicing research also works with subjects such as
Yigong Shi specializes in Cell biology, namely SMAD. His Biophysics study combines topics from a wide range of disciplines, such as Protein subunit, Gamma secretase, Transmembrane domain, Protein structure and Membrane protein. His Protein structure research is multidisciplinary, incorporating elements of Hydrolase and Proteasome.
The scientist’s investigation covers issues in RNA splicing, Biophysics, Spliceosome, Exon and Small nuclear RNA. His work deals with themes such as Messenger RNA, Stereochemistry and Intron, which intersect with RNA splicing. His Biophysics research includes elements of Gamma secretase, Transmembrane domain, Intramembrane protease, Protein structure and Membrane protein.
His biological study spans a wide range of topics, including Hydrolase, Cell biology, Proteasome and Proteases. His Spliceosome study combines topics in areas such as Molecular biology, Minor spliceosome, RNA Splicing Factors and snRNP. Cleavage is a subfield of Biochemistry that Yigong Shi investigates.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Mechanisms of TGF-β Signaling from Cell Membrane to the Nucleus
Yigong Shi;Joan Massagué.
The Galvanization of Biology: A Growing Appreciation for the Roles of Zinc
Jeremy M. Berg;Yigong Shi.
Molecular mechanisms of caspase regulation during apoptosis
Stefan J. Riedl;Yigong Shi.
Nature Reviews Molecular Cell Biology (2004)
Mechanisms of Caspase Activation and Inhibition during Apoptosis
Molecular Cell (2002)
A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis
Srinivasa M. Srinivasula;Ramesh Hegde;Ayman Saleh;Pinaki Datta.
Serine/Threonine Phosphatases: Mechanism through Structure
Crystal Structure of the PTEN Tumor Suppressor: Implications for Its Phosphoinositide Phosphatase Activity and Membrane Association
J.-O. Lee;Haijuan Yang;M.-M. Georgescu;A. Di Cristofano.
Structural and biochemical basis of apoptotic activation by Smac/DIABLO.
Jijie Chai;Chunying Du;Jia-Wei Wu;Saw Kyin.
Structural basis of IAP recognition by Smac/DIABLO
Geng Wu;Jijie Chai;Tomeka L. Suber;Jia-Wei Wu.
Crystal structure of a Smad MH1 domain bound to DNA: insights on DNA binding in TGF-beta signaling.
Yigong Shi;Yan-Fei Wang;Lata Jayaraman;Haijuan Yang.
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