What is he best known for?
The fields of study he is best known for:
His primary scientific interests are in Cell biology, Receptor, Signal transduction, SMAD and Transforming growth factor beta.
The concepts of his Cell biology study are interwoven with issues in Genetics and Ubiquitin ligase.
His Receptor research is multidisciplinary, relying on both Transforming growth factor and Kinase.
His biological study spans a wide range of topics, including Cancer research, Endocytosis, Internalization and Receptor complex.
His SMAD study combines topics in areas such as Cell, Embryonic stem cell, Xenopus, Nucleus and Stem cell.
His Transforming growth factor beta research incorporates elements of Interleukin-21 receptor and Growth factor receptor.
His most cited work include:
- Mechanism of activation of the TGF-β receptor (2072 citations)
- TGFβ signals through a heteromeric protein kinase receptor complex (1418 citations)
- The MAD-Related Protein Smad7 Associates with the TGFβ Receptor and Functions as an Antagonist of TGFβ Signaling (1203 citations)
What are the main themes of his work throughout his whole career to date?
Jeffrey L. Wrana spends much of his time researching Cell biology, Signal transduction, Molecular biology, Receptor and SMAD.
Jeffrey L. Wrana combines subjects such as Genetics and Biochemistry with his study of Cell biology.
His Signal transduction research includes elements of Cancer research, Bone morphogenetic protein and Transmembrane protein.
His study in Cancer research is interdisciplinary in nature, drawing from both Stem cell and Immunology.
His Molecular biology study integrates concerns from other disciplines, such as Cell culture and Osteopontin.
His Ubiquitin ligase study combines topics from a wide range of disciplines, such as Plasma protein binding and RHOA.
He most often published in these fields:
- Cell biology (83.20%)
- Signal transduction (37.21%)
- Molecular biology (20.16%)
What were the highlights of his more recent work (between 2014-2021)?
- Cell biology (83.20%)
- Signal transduction (37.21%)
- Hippo signaling pathway (13.44%)
In recent papers he was focusing on the following fields of study:
Jeffrey L. Wrana mainly focuses on Cell biology, Signal transduction, Hippo signaling pathway, Regeneration and Stem cell.
His research integrates issues of Cellular differentiation and Induced pluripotent stem cell in his study of Cell biology.
His research in Signal transduction intersects with topics in Cancer research, Cell migration, Cell growth and Cell polarity.
His study in Hippo signaling pathway is interdisciplinary in nature, drawing from both Signal transducing adaptor protein, Morphogenesis, Neurogenesis, Neuroscience and Transforming growth factor.
The concepts of his Stem cell study are interwoven with issues in Cancer, Wnt signaling pathway and Homeostasis.
His studies in SMAD integrate themes in fields like Bone morphogenetic protein and Effector.
Between 2014 and 2021, his most popular works were:
- Yap-dependent reprogramming of Lgr5 + stem cells drives intestinal regeneration and cancer (267 citations)
- Yap-dependent reprogramming of Lgr5 + stem cells drives intestinal regeneration and cancer (267 citations)
- Persistence of serum and saliva antibody responses to SARS-CoV-2 spike antigens in COVID-19 patients. (158 citations)
In his most recent research, the most cited papers focused on:
His primary areas of study are Cell biology, Hippo signaling pathway, Signal transduction, Regeneration and Immunology.
Jeffrey L. Wrana has included themes like Morphogenesis and Cellular differentiation in his Cell biology study.
As part of the same scientific family, Jeffrey L. Wrana usually focuses on Hippo signaling pathway, concentrating on SMAD and intersecting with Pathology, TGF beta signaling pathway, Renal fibrosis and Fibrosis.
His studies deal with areas such as Transport protein, Cadherin, VE-cadherin, Adherens junction and Intracellular as well as Signal transduction.
His Regeneration research includes elements of PI3K/AKT/mTOR pathway and Autocrine signalling.
His Immunology research is multidisciplinary, incorporating perspectives in Growth factor receptor and Saliva.
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