World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
86
Citations
24399
World Ranking
14239
National Ranking
591

Overview

Aaron D. Schimmer is affiliated with the Princess Margaret Cancer Centre in Canada. Their research focuses extensively on hematological malignancies, particularly acute myeloid leukemia (AML), as well as broader fields within medicine and molecular biology.

The primary fields of study in their work include Medicine and Biochemistry, Genetics and Molecular Biology, with significant contributions to subfields such as Molecular Biology, Hematology, Oncology, Genetics, and Public Health, Environmental and Occupational Health.

The main topics of research addressed in their publications cover:

  • Acute Myeloid Leukemia Research
  • Acute Lymphoblastic Leukemia Research
  • Chronic Myeloid Leukemia Treatments
  • Myeloproliferative Neoplasms: Diagnosis and Treatment
  • Histone Deacetylase Inhibitors Research
  • Ubiquitin and Proteasome Pathways
  • Protein Degradation and Inhibitors

Aaron D. Schimmer has contributed papers to several frequent publication venues, notably:

  • Blood
  • Cancer Research
  • Clinical Lymphoma Myeloma & Leukemia
  • Leukemia
  • Haematologica

They have collaborated frequently with several researchers, the most common co-authors being:

  • Mark D. Minden
  • Steven M. Chan
  • Karen Yee
  • Hassan Sibai
  • Andre C. Schuh

Their recent published papers include:

  • Activation of RAS/MAPK pathway confers MCL-1 mediated acquired resistance to BCL-2 inhibitor venetoclax in acute myeloid leukemia, 2022, Signal Transduction and Targeted Therapy
  • Venetoclax enhances T cell-mediated antileukemic activity by increasing ROS production, 2021, Blood
  • Mitochondrial ClpP serine protease-biological function and emerging target for cancer therapy, 2020, Cell Death and Disease
  • E1 Enzymes as Therapeutic Targets in Cancer, 2020, Pharmacological Reviews
  • Very long chain fatty acid metabolism is required in acute myeloid leukemia, 2021, Blood

Best Publications

  • Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia

    Liran I. Shlush;Sasan Zandi;Amanda Mitchell;Weihsu Claire Chen

  • A 17-gene stemness score for rapid determination of risk in acute leukaemia

    Stanley W. K. Ng;Amanda Mitchell;James A. Kennedy;James A. Kennedy;James A. Kennedy;Weihsu C. Chen

  • Anoikis resistance and tumor metastasis.

    Craig D. Simpson;Craig D. Simpson;Kika Anyiwe;Kika Anyiwe;Aaron D. Schimmer;Aaron D. Schimmer

  • Inhibitor of Apoptosis Proteins: Translating Basic Knowledge into Clinical Practice

    Aaron D. Schimmer

  • Inhibition of Mitochondrial Translation as a Therapeutic Strategy for Human Acute Myeloid Leukemia

    Marko Škrtić;Shrivani Sriskanthadevan;Bozhena Jhas;Marinella Gebbia

  • Small-molecule antagonists of apoptosis suppressor XIAP exhibit broad antitumor activity.

    Aaron D. Schimmer;Kate Welsh;Clemencia Pinilla;Zhiliang Wang

  • Myelodysplastic syndromes: the complexity of stem-cell diseases

    Seth J. Corey;Mark D. Minden;Dwayne L. Barber;Hagop M Kantarjian

  • Targeting XIAP for the treatment of malignancy

    A D Schimmer;S Dalili;S Dalili;R A Batey;S J Riedl

  • Mitochondrial ClpP-Mediated Proteolysis Induces Selective Cancer Cell Lethality

    Jo Ishizawa;Sarah F. Zarabi;Sarah F. Zarabi;R. Eric Davis;Ondrej Halgas;Ondrej Halgas

  • Inhibition of the Mitochondrial Protease ClpP as a Therapeutic Strategy for Human Acute Myeloid Leukemia

    Alicia Cole;Zezhou Wang;Etienne Coyaud;Veronique Voisin

  • Novel Proteasome Inhibitors to Overcome Bortezomib Resistance

    Amy M. Ruschak;Malik Slassi;Lewis E. Kay;Aaron D. Schimmer

  • Increased expression of apoptosis inhibitor protein XIAP contributes to anoikis resistance of circulating human prostate cancer metastasis precursor cells.

    Olga Berezovskaya;Aaron D. Schimmer;Anna B. Glinskii;Clemencia Pinilla

  • AML cells have low spare reserve capacity in their respiratory chain that renders them susceptible to oxidative metabolic stress

    Shrivani Sriskanthadevan;Danny V. Jeyaraju;Timothy E. Chung;Swayam Prabha

  • The triterpenoid CDDO induces apoptosis in refractory CLL B cells

    Irene M. Pedersen;Shinichi Kitada;Aaron Schimmer;Youngsoo Kim

  • Identification of 53 compounds that block Ebola virus-like particle entry via a repurposing screen of approved drugs

    Jennifer Kouznetsova;Wei Sun;Carles Martínez-Romero;Gregory Tawa

  • Mapping the Cellular Response to Small Molecules Using Chemogenomic Fitness Signatures

    Anna Y. Lee;Robert P. St.Onge;Michael J. Proctor;Iain M. Wallace

  • A phase I study of the pan bcl-2 family inhibitor obatoclax mesylate in patients with advanced hematologic malignancies.

    Aaron D. Schimmer;Susan O'Brien;Hagop Kantarjian;Joseph Brandwein

  • Dysregulation of apoptosis genes in hematopoietic malignancies.

    Shinichi Kitada;Irene M Pedersen;Aaron D Schimmer;John C Reed

  • Corrigendum: Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia

    Liran I. Shlush;Sasan Zandi;Amanda Mitchell;Weihsu Claire Chen

  • Mapping the Cellular Response to Small Molecules Using Chemogenomic Fitness Signatures

    A. Y. Lee;R. P. St.Onge;M. J. Proctor;I. M. Wallace

Frequent Co-Authors

Mark D. Minden
Mark D. Minden Princess Margaret Cancer Centre
Vikas Gupta
Vikas Gupta Princess Margaret Cancer Centre
Alessandro Datti
Alessandro Datti University of Perugia
Suzanne Kamel-Reid
Suzanne Kamel-Reid University Health Network
Gary Rodin
Gary Rodin Princess Margaret Cancer Centre
Jeffrey L. Wrana
Jeffrey L. Wrana Lunenfeld-Tanenbaum Research Institute
Camilla Zimmermann
Camilla Zimmermann University of Toronto
Wei Xu
Wei Xu Shenzhen University
Gary D. Bader
Gary D. Bader University of Toronto
David W. Hedley
David W. Hedley Princess Margaret Cancer Centre

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring alternatives to studying Medicine in the USA can open rewarding career pathways in the healthcare sector. Many students seek flexible options that allow for impactful roles without the commitment of a traditional medical doctorate. Online degrees offer flexibility, affordability, and diverse specializations to match your preferred healthcare field.

For those interested in healthcare management, a degree such as the online master of health administration can lead to leadership roles in hospitals, clinics, and health organizations. Some may consider enrolling in online mha programs affordable to obtain high-quality education without overwhelming debt.

Nurses looking to advance their clinical skills may explore cheap dnp online programs, which are designed for those pursuing top nursing roles and specialized positions. Similarly, students interested in pharmaceuticals can further their training through an online pharmd and step into critical patient care and research positions.

Carefully researching accredited and cost-effective online programs can help you find the best fit for your goals.

Best Scientists Citing Aaron D. Schimmer

Trending Scientists

Recently Published Articles