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Medicine

D-Index
103
Citations
42320
World Ranking
7317
National Ranking
3830

Overview

Nezam H. Afdhal is affiliated with Beth Israel Deaconess Medical Center in the United States and has contributed extensively to the field of medicine, with a particular focus on hepatology. Their research spans several specific subfields including hepatology, epidemiology, infectious diseases, rheumatology, and genetics.

The scientist has published numerous papers, with a significant subset addressing liver disease diagnosis and treatment, hepatitis C virus research, hepatitis B virus studies, liver disease and transplantation, liver diseases and immunity, systemic lupus erythematosus research, and HIV/AIDS drug development and treatment.

Some recent notable publications include:

  • "Cirrhosis regression is associated with improved clinical outcomes in patients with nonalcoholic steatohepatitis," 2021, Hepatology
  • "Liver stiffness thresholds to predict disease progression and clinical outcomes in bridging fibrosis and cirrhosis," 2022, Gut
  • "Fibrosis-4 Index Can Independently Predict Major Adverse Cardiovascular Events in Nonalcoholic Fatty Liver Disease," 2022, The American Journal of Gastroenterology
  • "Fibrosis-4 Index as an Independent Predictor of Mortality and Liver-Related Outcomes in NAFLD," 2021, Hepatology Communications
  • "A Machine Learning Approach to Liver Histological Evaluation Predicts Clinically Significant Portal Hypertension in NASH Cirrhosis," 2021, Hepatology

Throughout their career, the scientist has frequently published in several venues including:

  • Journal of Hepatology
  • UNC Libraries
  • Hepatology Communications
  • Value in Health
  • Hepatology

Frequent collaborative partnerships have been established with several researchers in the field. Key coauthors include:

  • Scott Milligan
  • Zobair M. Younossi
  • Michael P. Curry
  • Michelle Lai
  • Andrew Frick

The main scientific contribution of Nezam H. Afdhal centers on liver diseases, with particular attention to nonalcoholic fatty liver disease, viral hepatitis, and pathological mechanisms related to liver fibrosis and cirrhosis. Their work also intersects with cardiovascular risks associated with liver conditions and employs modern approaches such as machine learning for clinical predictions.

Best Publications

  • Ledipasvir and Sofosbuvir for Untreated HCV Genotype 1 Infection

    Nezam Afdhal;Stefan Zeuzem;Paul Kwo;Mario Chojkier

  • Regression of cirrhosis during treatment with tenofovir disoproxil fumarate for chronic hepatitis B: a 5-year open-label follow-up study

    Patrick Marcellin;Edward J Gane;Maria Buti;Nezam H Afdhal

  • Ledipasvir and Sofosbuvir for Previously Treated HCV Genotype 1 Infection

    Nezam Afdhal;K. Rajender Reddy;David R. Nelson;Eric Lawitz

  • Response-guided Telaprevir Combination Treatment for Hepatitis C Virus Infection

    Kenneth K.E. Sherman;Steven S.L. Flamm;Nezam N.H. Afdhal;David Nelson

  • Sofosbuvir and Velpatasvir for HCV Genotype 2 and 3 Infection

    Graham R. Foster;Nezam Afdhal;Stuart K. Roberts;Norbert Bräu

  • Telaprevir for previously treated chronic HCV infection.

    John G. McHutchison;Michael P. Manns;Andrew J. Muir;Norah A. Terrault

  • Interleukin-28B Polymorphism Improves Viral Kinetics and Is the Strongest Pretreatment Predictor of Sustained Virologic Response in Genotype 1 Hepatitis C Virus

    Alexander J. Thompson;Andrew J. Muir;Andrew J. Muir;Mark S. Sulkowski;Dongliang Ge

  • Evaluation of liver fibrosis: a concise review.

    Nezam H Afdhal;David Nunes

  • Ledipasvir and Sofosbuvir Plus Ribavirin for Treatment of HCV Infection in Patients With Advanced Liver Disease

    Michael Charlton;Gregory T. Everson;Steven L. Flamm;Princy Kumar

  • Thrombocytopenia associated with chronic liver disease

    Nezam Afdhal;John McHutchison;Robert Brown;Ira Jacobson

  • Peginterferon and ribavirin treatment in African American and Caucasian American patients with hepatitis C genotype 1.

    Hari S. Conjeevaram;Michael W. Fried;Lennox J. Jeffers;Norah A. Terrault

  • Diagnosis and quantitation of fibrosis.

    Diarmuid S. Manning;Nezam H. Afdhal

  • Eltrombopag for thrombocytopenia in patients with cirrhosis associated with hepatitis C.

    John G. McHutchison;Geoffrey Dusheiko;Mitchell L. Shiffman;Maribel Rodriguez-Torres

  • Helicobacter pylori moves through mucus by reducing mucin viscoelasticity

    Jonathan P. Celli;Bradley S. Turner;Nezam H. Afdhal;Sarah Keates

  • The ASK1 inhibitor selonsertib in patients with nonalcoholic steatohepatitis: A randomized, phase 2 trial

    Rohit Loomba;Eric Lawitz;Parvez S. Mantry;Saumya Jayakumar

  • The natural history of hepatitis C.

    Nezam H Afdhal

  • IL28B genotype is associated with differential expression of intrahepatic interferon‐stimulated genes in patients with chronic hepatitis C

    Thomas J. Urban;Alexander J. Thompson;Shelton S. Bradrick;Jacques Fellay

  • Epoetin alfa maintains ribavirin dose in HCV-infected patients: a prospective, double-blind, randomized controlled study.

    Nezam H. Afdhal;Douglas T. Dieterich;Paul J. Pockros;Eugene R. Schiff

  • The clinical significance of persistently normal ALT in chronic hepatitis B infection.

    Michelle Lai;Benjamin J. Hyatt;Imad Nasser;Michael Curry

  • Sofosbuvir and Ribavirin Prevent Recurrence of HCV Infection After Liver Transplantation: An Open-Label Study

    Michael P. Curry;Xavier Forns;Raymond T. Chung;Norah A. Terrault

Frequent Co-Authors

John G. McHutchison
John G. McHutchison Duke University
Zobair M. Younossi
Zobair M. Younossi Inova Health System
Mark S. Sulkowski
Mark S. Sulkowski Johns Hopkins University School of Medicine
Bruce R. Bacon
Bruce R. Bacon Saint Louis University
Ira M. Jacobson
Ira M. Jacobson New York University
Andrew J. Muir
Andrew J. Muir Duke University
Eric Lawitz
Eric Lawitz The University of Texas at Austin
Zachary Goodman
Zachary Goodman Inova Fairfax Hospital
Mitchell L. Shiffman
Mitchell L. Shiffman Bon Secours Health System
K. Rajender Reddy
K. Rajender Reddy University of Pennsylvania

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