D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 43 Citations 6,486 128 World Ranking 16804 National Ranking 513

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Cancer

Cancer research, Leukemia, Myeloid leukemia, Stem cell and Kinome are his primary areas of study. Alessandro Datti has researched Cancer research in several fields, including Cell culture, Protein kinase B, Kinase and Internal medicine. The various areas that Alessandro Datti examines in his Myeloid leukemia study include Antileukemic agent and Pharmacology.

His work deals with themes such as Cell and Mitochondrion, which intersect with Stem cell. His study in Kinome is interdisciplinary in nature, drawing from both Regulator, Serrate-Jagged Proteins and Small interfering RNA. His biological study spans a wide range of topics, including Cancer stem cell, Virology and Mitochondrial biogenesis.

His most cited work include:

  • Functional Genomics Reveals a BMP-Driven Mesenchymal-to-Epithelial Transition in the Initiation of Somatic Cell Reprogramming (800 citations)
  • Inhibition of Mitochondrial Translation as a Therapeutic Strategy for Human Acute Myeloid Leukemia (369 citations)
  • Inhibition of Mitochondrial Translation as a Therapeutic Strategy for Human Acute Myeloid Leukemia (369 citations)

What are the main themes of his work throughout his whole career to date?

Alessandro Datti mainly focuses on Cancer research, Biochemistry, Cell biology, Pharmacology and Cell culture. His Cancer research research incorporates elements of Head and neck cancer, Apoptosis, Cell cycle, Kinase and In vivo. His Biochemistry research is multidisciplinary, incorporating elements of Molecular biology and Bone resorption.

Alessandro Datti works in the field of Cell biology, focusing on Mitochondrion in particular. Alessandro Datti combines subjects such as Daunorubicin, Leukemia, Myeloid leukemia and Stem cell with his study of Pharmacology. In Myeloid leukemia, Alessandro Datti works on issues like Progenitor cell, which are connected to Mitochondrial biogenesis.

He most often published in these fields:

  • Cancer research (57.83%)
  • Biochemistry (24.70%)
  • Cell biology (19.28%)

What were the highlights of his more recent work (between 2015-2021)?

  • Cancer research (57.83%)
  • Cell culture (16.87%)
  • In vivo (14.46%)

In recent papers he was focusing on the following fields of study:

The scientist’s investigation covers issues in Cancer research, Cell culture, In vivo, Cell biology and Cell cycle. His work carried out in the field of Cancer research brings together such families of science as Cancer, Breast cancer, Anaplastic thyroid cancer, Cell growth and Kinase. The Cell culture study combines topics in areas such as Head and neck cancer, Chemotherapy, Inhibitory postsynaptic potential, Pathology and High-throughput screening.

His In vivo study combines topics from a wide range of disciplines, such as Targeted therapy and Syk. His work in the fields of Cell biology, such as Mitochondrion, overlaps with other areas such as Germination. The study incorporates disciplines such as Tyrosine kinase and Myeloid leukemia in addition to Pharmacology.

Between 2015 and 2021, his most popular works were:

  • RB1 deficiency in triple-negative breast cancer induces mitochondrial protein translation (64 citations)
  • Multilayered Control of Alternative Splicing Regulatory Networks by Transcription Factors (62 citations)
  • Identification of CDC25 as a Common Therapeutic Target for Triple-Negative Breast Cancer. (37 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Cancer

His primary areas of investigation include Cancer research, PTEN, Breast cancer, PI3K/AKT/mTOR pathway and Cell biology. Alessandro Datti interconnects Soft tissue sarcoma, Protein kinase B, Cell growth, Cancer cell and Triple-negative breast cancer in the investigation of issues within Cancer research. His Triple-negative breast cancer research is multidisciplinary, incorporating perspectives in Cyclin-dependent kinase 1, Wee1, Regulation of gene expression and Kinome.

His PTEN research incorporates themes from Metastasis, Claudin-Low, Surgical oncology, Transplantation and Adenocarcinoma. Alessandro Datti has researched PI3K/AKT/mTOR pathway in several fields, including Bioinformatics, Leiomyosarcoma, Doxorubicin, Sarcoma and Kinase. He combines subjects such as Downregulation and upregulation and Neuroprotection with his study of Cell biology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Functional Genomics Reveals a BMP-Driven Mesenchymal-to-Epithelial Transition in the Initiation of Somatic Cell Reprogramming

Payman Samavarchi-Tehrani;Azadeh Golipour;Azadeh Golipour;Laurent David;Hoon Ki Sung.
Cell Stem Cell (2010)

1068 Citations

Inhibition of Mitochondrial Translation as a Therapeutic Strategy for Human Acute Myeloid Leukemia

Marko Škrtić;Shrivani Sriskanthadevan;Bozhena Jhas;Marinella Gebbia.
Cancer Cell (2011)

546 Citations

Systematic exploration of essential yeast gene function with temperature-sensitive mutants

Zhijian Li;Franco J. Vizeacoumar;Sondra Bahr;Jingjing Li.
Nature Biotechnology (2011)

387 Citations

Essential Gene Profiles in Breast, Pancreatic, and Ovarian Cancer Cells

Richard Marcotte;Kevin R. Brown;Fernando Suarez;Azin Sayad.
Cancer Discovery (2012)

341 Citations

Chelation of intracellular iron with the antifungal agent ciclopirox olamine induces cell death in leukemia and myeloma cells.

Yanina Eberhard;Sean P. McDermott;Xiaoming Wang;Marcela Gronda.
Blood (2009)

167 Citations

Lysosomal disruption preferentially targets acute myeloid leukemia cells and progenitors

Mahadeo A. Sukhai;Swayam Prabha;Rose Hurren;Angela C. Rutledge.
Journal of Clinical Investigation (2013)

138 Citations

Targeting Mitochondria with Avocatin B Induces Selective Leukemia Cell Death

Eric A. Lee;Leonard Angka;Sarah-Grace Rota;Thomas Hanlon.
Cancer Research (2015)

128 Citations

High throughput kinase inhibitor screens reveal TRB3 and MAPK-ERK/TGFβ pathways as fundamental Notch regulators in breast cancer

Julia Izrailit;Hal K. Berman;Hal K. Berman;Alessandro Datti;Alessandro Datti;Jeffrey L. Wrana.
Proceedings of the National Academy of Sciences of the United States of America (2013)

125 Citations

The MMS22L-TONSL complex mediates recovery from replication stress and homologous recombination

Lara O'Donnell;Stephanie Panier;Stephanie Panier;Jan Wildenhain;Johnny M. Tkach.
Molecular Cell (2010)

121 Citations

Inhibition of the sodium potassium adenosine triphosphatase pump sensitizes cancer cells to anoikis and prevents distant tumor formation.

Craig D. Simpson;Imtiaz A. Mawji;Kika Anyiwe;Moyo A. Williams.
Cancer Research (2009)

119 Citations

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