World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
142
Citations
117675
World Ranking
1532
National Ranking
890

James R. Downing publication distribution in Medicine in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Medicine in 2026. The highlighted bar marks where James R. Downing sits on this spectrum.

101–120 publications: 5 scientists 121–140 publications: 26 scientists 141–160 publications: 73 scientists 161–180 publications: 155 scientists 181–200 publications: 230 scientists 201–220 publications: 363 scientists 221–240 publications: 487 scientists 241–260 publications: 545 scientists 261–280 publications: 722 scientists 281–300 publications: 768 scientists 301–320 publications: 834 scientists 321–340 publications: 895 scientists 341–360 publications: 922 scientists 361–380 publications: 838 scientists 381–400 publications: 861 scientists 401–420 publications: 918 scientists 421–440 publications: 806 scientists 441–460 publications: 771 scientists 461–480 publications: 751 scientists 481–500 publications: 713 scientists 501–520 publications: 617 scientists 521–540 publications: 611 scientists 541–560 publications: 537 scientists 561–580 publications: 504 scientists 581–600 publications: 509 scientists 601–620 publications: 396 scientists 621–640 publications: 386 scientists 641–660 publications: 371 scientists 661–680 publications: 340 scientists 681–700 publications: 336 scientists 701–720 publications: 307 scientists 721–740 publications: 259 scientists 741–760 publications: 230 scientists 761–780 publications: 228 scientists 781–800 publications: 217 scientists 801–820 publications: 204 scientists 821–840 publications: 186 scientists 841–860 publications: 177 scientists 861–880 publications: 155 scientists 881–900 publications: 139 scientists 901–920 publications: 145 scientists 921–940 publications: 116 scientists 941–960 publications: 133 scientists 961–980 publications: 91 scientists 981–1,000 publications: 96 scientists 1,001–1,020 publications: 77 scientists 1,021–1,040 publications: 70 scientists 1,041–1,060 publications: 63 scientists 1,061–1,080 publications: 77 scientists 1,081–1,100 publications: 49 scientists 1,101–1,120 publications: 54 scientists 1,121–1,140 publications: 49 scientists 1,141–1,160 publications: 51 scientists 1,161–1,180 publications: 35 scientists 1,181–1,200 publications: 39 scientists 1,201–1,220 publications: 26 scientists 1,221–1,240 publications: 37 scientists 1,241–1,260 publications: 36 scientists 1,261–1,280 publications: 27 scientists 1,281–1,300 publications: 32 scientists 1,301–1,320 publications: 28 scientists 1,321–1,340 publications: 17 scientists 1,341–1,360 publications: 30 scientists 1,361–1,380 publications: 28 scientists 1,381–1,400 publications: 17 scientists 1,401–1,420 publications: 21 scientists 1,421–1,440 publications: 15 scientists 1,441–1,460 publications: 12 scientists 1,461–1,480 publications: 12 scientists 1,481–1,500 publications: 18 scientists 1,501–1,520 publications: 14 scientists 1,521–1,540 publications: 17 scientists 1,541–1,560 publications: 15 scientists 1,561–1,580 publications: 6 scientists 1,581–1,600 publications: 2 scientists 1,601–1,620 publications: 12 scientists 1,621–1,640 publications: 11 scientists 1,641–1,660 publications: 8 scientists 1,661–1,680 publications: 5 scientists 1,681–1,700 publications: 5 scientists 1,701–1,720 publications: 10 scientists 1,721–1,740 publications: 12 scientists 1,741–1,760 publications: 14 scientists 1,761–1,780 publications: 6 scientists 1,781–1,795 publications: 5 scientists 1,796+ publications: 100 scientists
101 publications 1,796+

This scientist: 462 publications — 51st percentile

51% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,796 publications or more.

James R. Downing D-index placement in Medicine in 2026

The chart shows the D-index (discipline H-index) distribution of Medicine scientists ranked by Research.com in 2026. The highlighted bar marks where James R. Downing sits on this spectrum.

70–71 D-Index: 226 scientists 72–73 D-Index: 391 scientists 74–75 D-Index: 574 scientists 76–77 D-Index: 730 scientists 78–79 D-Index: 891 scientists 80–81 D-Index: 972 scientists 82–83 D-Index: 1,027 scientists 84–85 D-Index: 1,003 scientists 86–87 D-Index: 960 scientists 88–89 D-Index: 970 scientists 90–91 D-Index: 922 scientists 92–93 D-Index: 839 scientists 94–95 D-Index: 808 scientists 96–97 D-Index: 779 scientists 98–99 D-Index: 668 scientists 100–101 D-Index: 611 scientists 102–103 D-Index: 630 scientists 104–105 D-Index: 513 scientists 106–107 D-Index: 541 scientists 108–109 D-Index: 445 scientists 110–111 D-Index: 429 scientists 112–113 D-Index: 400 scientists 114–115 D-Index: 393 scientists 116–117 D-Index: 318 scientists 118–119 D-Index: 302 scientists 120–121 D-Index: 287 scientists 122–123 D-Index: 255 scientists 124–125 D-Index: 256 scientists 126–127 D-Index: 252 scientists 128–129 D-Index: 230 scientists 130–131 D-Index: 179 scientists 132–133 D-Index: 168 scientists 134–135 D-Index: 163 scientists 136–137 D-Index: 159 scientists 138–139 D-Index: 134 scientists 140–141 D-Index: 134 scientists 142–143 D-Index: 118 scientists 144–145 D-Index: 109 scientists 146–147 D-Index: 106 scientists 148–149 D-Index: 74 scientists 150–151 D-Index: 79 scientists 152–153 D-Index: 80 scientists 154–155 D-Index: 87 scientists 156–157 D-Index: 57 scientists 158–159 D-Index: 74 scientists 160–161 D-Index: 69 scientists 162–163 D-Index: 60 scientists 164–165 D-Index: 53 scientists 166–167 D-Index: 39 scientists 168–169 D-Index: 42 scientists 170–171 D-Index: 32 scientists 172–173 D-Index: 39 scientists 174–175 D-Index: 40 scientists 176–177 D-Index: 28 scientists 178–179 D-Index: 19 scientists 180–181 D-Index: 23 scientists 182–183 D-Index: 31 scientists 184–185 D-Index: 18 scientists 186–187 D-Index: 20 scientists 188–189 D-Index: 22 scientists 190–191 D-Index: 13 scientists 192–193 D-Index: 21 scientists 194–195 D-Index: 12 scientists 196–197 D-Index: 12 scientists 198–199 D-Index: 14 scientists 200–201 D-Index: 15 scientists 202–203 D-Index: 13 scientists 204–205 D-Index: 10 scientists 206–207 D-Index: 8 scientists 208–209 D-Index: 4 scientists 210–211 D-Index: 12 scientists 212–213 D-Index: 11 scientists 214–215 D-Index: 10 scientists 216 D-Index: 4 scientists 217+ D-Index: 98 scientists
70 D-Index 217+

This scientist: 142 D-Index — 92nd percentile

92% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 217 D-Index or more.

Research.com Recognitions

  • 2016 - Fellow of the American Academy of Arts and Sciences
  • 2003 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

James R. Downing is affiliated with St. Jude Children's Research Hospital in the United States. Their research primarily spans several interconnected fields within biomedical science, including Medicine and Biochemistry, Genetics and Molecular Biology. The subfields most frequently associated with their work include Molecular Biology, Pediatrics, Perinatology and Child Health, Public Health, Environmental and Occupational Health, Cancer Research, and Hematology.

Downing's scientific contributions encompass a range of topics with a focus on leukemia and childhood cancers. Key research topics include:

  • Acute Lymphoblastic Leukemia research
  • Acute Myeloid Leukemia Research
  • Childhood Cancer Survivors' Quality of Life
  • Epigenetics and DNA Methylation
  • Cancer Genomics and Diagnostics
  • Neuroblastoma Research and Treatments
  • Lung Cancer Research Studies

Among the recent papers authored or co-authored by Downing are:

  • The genomic landscape of pediatric acute lymphoblastic leukemia, published in 2022 in Nature Genetics
  • St. Jude Cloud: A Pediatric Cancer Genomic Data-Sharing Ecosystem, published in 2021 in Cancer Discovery
  • Pan-neuroblastoma analysis reveals age- and signature-associated driver alterations, published in 2020 in Nature Communications
  • Clinical Significance of Novel Subtypes of Acute Lymphoblastic Leukemia in the Context of Minimal Residual Disease-Directed Therapy, published in 2021 in Blood Cancer Discovery
  • MYCN amplification and ATRX mutations are incompatible in neuroblastoma, published in 2020 in Nature Communications

Frequent co-authors who have collaborated with Downing include:

  • Jinghui Zhang
  • Charles G. Mullighan
  • Michael Rusch
  • John Easton
  • Yu Liu

The venues where Downing has regularly published research work include:

  • Zenodo (CERN European Organization for Nuclear Research)
  • Blood Cancer Discovery
  • Cancer Research
  • Nature Communications
  • Leukemia

Over the course of their career, Downing has received recognition in the form of awards such as the Fellow of the American Academy of Arts and Sciences in 2016 and Fellow of the American Association for the Advancement of Science (AAAS) in 2003.

Best Publications

  • Molecular classification of cancer: class discovery and class prediction by gene expression monitoring.

    T. R. Golub;T. R. Golub;D. K. Slonim;P. Tamayo;C. Huard

  • MicroRNA expression profiles classify human cancers

    Jun Lu;Gad Getz;Eric A. Miska;Eric A. Miska;Ezequiel Alvarez-Saavedra

  • Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia

    Timothy J. Ley;Christopher Miller;Li Ding;Benjamin J. Raphael

  • Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling.

    Eng Juh Yeoh;Mary E. Ross;Sheila A. Shurtleff;W. Kent Williams

  • AML1, the Target of Multiple Chromosomal Translocations in Human Leukemia, Is Essential for Normal Fetal Liver Hematopoiesis

    Tsukasa Okuda;Jan van Deursen;Scott W Hiebert;Gerard Grosveld

  • Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia

    Charles G. Mullighan;Salil Goorha;Ina Radtke;Christopher B. Miller

  • Data-Driven Phenotypic Dissection of AML Reveals Progenitor-like Cells that Correlate with Prognosis.

    Jacob H. Levine;Erin F. Simonds;Sean C. Bendall;Kara L. Davis

  • Tumor Suppression at the Mouse INK4a Locus Mediated by the Alternative Reading Frame Product p19 ARF

    Takehiko Kamijo;Frederique Zindy;Martine F. Roussel;Dawn E. Quelle

  • The genetic basis of early T-cell precursor acute lymphoblastic leukaemia

    Jinghui Zhang;Li Ding;Linda Holmfeldt;Gang Wu

  • Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas

    Gang Wu;Alberto Broniscer;Troy A McEachron;Charles Lu

  • Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia.

    Charles G Mullighan;Xiaoping Su;Jinghui Zhang;Ina Radtke

  • Targetable Kinase-Activating Lesions in Ph-like Acute Lymphoblastic Leukemia

    K. G. Roberts;Y. Li;D. Payne-Turner;R. C. Harvey

  • Treating childhood acute lymphoblastic leukemia without cranial irradiation.

    Ching Hon Pui;Dario Campana;Deqing Pei;W. Paul Bowman

  • Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia

    Adolfo A Ferrando;Donna S Neuberg;Jane Staunton;Mignon L Loh

  • Germline Mutations in Predisposition Genes in Pediatric Cancer

    Jinghui Zhang;Michael F. Walsh;Gang Wu;Michael N. Edmonson

  • BCR–ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros

    Charles G. Mullighan;Christopher B. Miller;Ina Radtke;Letha A. Phillips

  • Early T-cell precursor leukaemia: a subtype of very high-risk acute lymphoblastic leukaemia

    Elaine Coustan-Smith;Charles G. Mullighan;Mihaela Onciu;Frederick G. Behm

  • The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma

    Gang Wu;Alexander K Diaz;Alexander K Diaz;Barbara S Paugh;Sherri L Rankin

  • Childhood Acute Lymphoblastic Leukemia: Progress Through Collaboration

    Ching Hon Pui;Jun J. Yang;Stephen P. Hunger;Rob Pieters

  • Genomic Analysis of the Clonal Origins of Relapsed Acute Lymphoblastic Leukemia

    Charles G. Mullighan;Letha A. Phillips;Xiaoping Su;Jing Ma

Frequent Co-Authors

Jinghui Zhang
Jinghui Zhang St. Jude Children's Research Hospital
Charles G. Mullighan
Charles G. Mullighan St. Jude Children's Research Hospital
Ching-Hon Pui
Ching-Hon Pui St. Jude Children's Research Hospital
Sheila A. Shurtleff
Sheila A. Shurtleff St. Jude Children's Research Hospital
John Easton
John Easton St. Jude Children's Research Hospital
Susana C. Raimondi
Susana C. Raimondi St. Jude Children's Research Hospital
Michael Rusch
Michael Rusch St. Jude Children's Research Hospital
Jeffrey E. Rubnitz
Jeffrey E. Rubnitz St. Jude Children's Research Hospital
Gang Wu
Gang Wu Washington University in St. Louis
Mary V. Relling
Mary V. Relling St. Jude Children's Research Hospital

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