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2025

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Best Scientists

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183
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Medicine

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189
Citations
130072
World Ranking
267
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Research.com Recognitions

  • 2025 - Research.com Best Scientists Award
  • 1998 - Fellow of the American Association for the Advancement of Science (AAAS)
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Ching-Hon Pui is affiliated with St. Jude Children's Research Hospital in the United States. Their research primarily focuses on pediatrics, hematology, oncology, and molecular biology, with a substantial emphasis on pediatric acute lymphoblastic leukemia (ALL) and related hematologic malignancies.

Their recent notable publications include:

  • International Consensus Classification of Myeloid Neoplasms and Acute Leukemias: integrating morphologic, clinical, and genomic data, 2022, Blood
  • The genomic landscape of pediatric acute lymphoblastic leukemia, 2022, Nature Genetics
  • Effect of Dasatinib vs Imatinib in the Treatment of Pediatric Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia, 2020, JAMA Oncology
  • Advances in the Diagnosis and Treatment of Pediatric Acute Lymphoblastic Leukemia, 2021, Journal of Clinical Medicine
  • Enhancer Hijacking Drives Oncogenic BCL11B Expression in Lineage-Ambiguous Stem Cell Leukemia, 2021, Cancer Discovery

Frequent co-authors include:

  • Jun J. Yang
  • Hiroto Inaba
  • Sima Jeha
  • Mary V. Relling
  • Wenjian Yang

Ching-Hon Pui has published extensively in several scientific journals, with the most frequent venues being:

  • Blood
  • Clinical Lymphoma Myeloma & Leukemia
  • Journal of Clinical Oncology
  • Leukemia
  • Cancer

Their work spans several fields of study mainly under Medicine, with important subfields including:

  • Public Health, Environmental and Occupational Health
  • Pediatrics, Perinatology and Child Health
  • Hematology
  • Molecular Biology
  • Oncology

Main research topics covered by Ching-Hon Pui include:

  • Acute Lymphoblastic Leukemia research
  • Childhood Cancer Survivors' Quality of Life
  • Acute Myeloid Leukemia Research
  • Chronic Myeloid Leukemia Treatments
  • CAR-T cell therapy research
  • Epigenetics and DNA Methylation
  • Chronic Lymphocytic Leukemia Research

Recognition of Ching-Hon Pui's professional contributions includes being named a Fellow of the American Association for the Advancement of Science (AAAS) in 1998 and membership in the Association of American Physicians.

Best Publications

  • Treatment of acute lymphoblastic leukemia.

    Ching-Hon Pui;William E Evans

  • Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling.

    Eng Juh Yeoh;Mary E. Ross;Sheila A. Shurtleff;W. Kent Williams

  • Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia

    Charles G. Mullighan;Salil Goorha;Ina Radtke;Christopher B. Miller

  • Acute lymphoblastic leukaemia

    Ching-Hon Pui;Leslie L Robison;A Thomas Look

  • The genetic basis of early T-cell precursor acute lymphoblastic leukaemia

    Jinghui Zhang;Li Ding;Linda Holmfeldt;Gang Wu

  • Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia.

    Charles G Mullighan;Xiaoping Su;Jinghui Zhang;Ina Radtke

  • Targetable Kinase-Activating Lesions in Ph-like Acute Lymphoblastic Leukemia

    K. G. Roberts;Y. Li;D. Payne-Turner;R. C. Harvey

  • Treating childhood acute lymphoblastic leukemia without cranial irradiation.

    Ching Hon Pui;Dario Campana;Deqing Pei;W. Paul Bowman

  • Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia

    Adolfo A Ferrando;Donna S Neuberg;Jane Staunton;Mignon L Loh

  • Germline Mutations in Predisposition Genes in Pediatric Cancer

    Jinghui Zhang;Michael F. Walsh;Gang Wu;Michael N. Edmonson

  • BCR–ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros

    Charles G. Mullighan;Christopher B. Miller;Ina Radtke;Letha A. Phillips

  • Early T-cell precursor leukaemia: a subtype of very high-risk acute lymphoblastic leukaemia

    Elaine Coustan-Smith;Charles G. Mullighan;Mihaela Onciu;Frederick G. Behm

  • Uniform approach to risk classification and treatment assignment for children with acute lymphoblastic leukemia.

    M Smith;D Arthur;B Camitta;A J Carroll

  • Biology, Risk Stratification, and Therapy of Pediatric Acute Leukemias: An Update

    Ching Hon Pui;William L. Carroll;Soheil Meshinchi;Robert J. Arceci

  • The tumor lysis syndrome.

    Scott C. Howard;Deborah P. Jones;Ching-Hon Pui

  • Molecular diagnosis of thiopurine S-methyltransferase deficiency: Genetic basis for azathioprine and mercaptopurine intolerance

    Charles R. Yates;Eugene Y. Krynetski;Thrina Loennechen;Michael Y. Fessing

  • Childhood Acute Lymphoblastic Leukemia: Progress Through Collaboration

    Ching Hon Pui;Jun J. Yang;Stephen P. Hunger;Rob Pieters

  • Guidelines for the Management of Pediatric and Adult Tumor Lysis Syndrome: An Evidence-Based Review

    Bertrand Coiffier;Arnold Altman;Ching-Hon Pui;Anas Younes

  • Mercaptopurine Therapy Intolerance and Heterozygosity at the Thiopurine S-Methyltransferase Gene Locus

    Mary V. Relling;Michael L. Hancock;Gaston K. Rivera;John T. Sandlund

  • Acute myeloid leukemia in children treated with epipodophyllotoxins for acute lymphoblastic leukemia.

    C H Pui;R C Ribeiro;M L Hancock;G K Rivera

Frequent Co-Authors

Mary V. Relling
Mary V. Relling St. Jude Children's Research Hospital
William E. Evans
William E. Evans St. Jude Children's Research Hospital
Raul C. Ribeiro
Raul C. Ribeiro St. Jude Children's Research Hospital
Jeffrey E. Rubnitz
Jeffrey E. Rubnitz St. Jude Children's Research Hospital
John T. Sandlund
John T. Sandlund National Institutes of Health
Susana C. Raimondi
Susana C. Raimondi St. Jude Children's Research Hospital
James R. Downing
James R. Downing St. Jude Children's Research Hospital
Dario Campana
Dario Campana National University of Singapore
Melissa M. Hudson
Melissa M. Hudson St. Jude Children's Research Hospital
Gaston K. Rivera
Gaston K. Rivera St. Jude Children's Research Hospital

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