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119
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56059
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Overview

Stephen P. Hunger is affiliated with the University of Pennsylvania in the United States and has contributed extensively to the field of medicine, with a particular focus on public health, pediatrics, hematology, molecular biology, and oncology.

The scientist's research primarily centers on acute lymphoblastic leukemia (ALL) and related hematological malignancies. Major research topics include:

  • Acute Lymphoblastic Leukemia research
  • Childhood Cancer Survivors' Quality of Life
  • Acute Myeloid Leukemia Research
  • Chronic Myeloid Leukemia Treatments
  • Lymphoma Diagnosis and Treatment
  • Chronic Lymphocytic Leukemia Research
  • Epigenetics and DNA Methylation

Frequent co-authors collaborating with Stephen P. Hunger include:

  • Mignon L. Loh
  • Meenakshi Devidas
  • Elizabeth A. Raetz
  • Naomi Winick
  • Brent L. Wood

Most publications have appeared in the following venues, reflecting the emphasis on hematology and oncology:

  • Blood
  • Journal of Clinical Oncology
  • Pediatric Blood & Cancer
  • Haematologica
  • Leukemia

Some recent and notable papers authored or co-authored by the scientist are:

  • The genomic landscape of pediatric acute lymphoblastic leukemia, 2022, Nature Genetics
  • Effect of Postreinduction Therapy Consolidation With Blinatumomab vs Chemotherapy on Disease-Free Survival in Children, Adolescents, and Young Adults With First Relapse of B-Cell Acute Lymphoblastic Leukemia, 2021, JAMA
  • Children's Oncology Group AALL0434: A Phase III Randomized Clinical Trial Testing Nelarabine in Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia, 2020, Journal of Clinical Oncology
  • How I treat relapsed acute lymphoblastic leukemia in the pediatric population, 2020, Blood
  • Enhancer Hijacking Drives Oncogenic BCL11B Expression in Lineage-Ambiguous Stem Cell Leukemia, 2021, Cancer Discovery

The scientist's work reflects a multidisciplinary approach involving clinical trials, genomic analysis, and therapeutic strategies in pediatric and young adult populations affected by leukemia. The integration of molecular biology techniques with clinical oncology enables comprehensive insights into disease mechanisms and treatment outcomes.

Best Publications

  • Acute Lymphoblastic Leukemia in Children

    Stephen P. Hunger;Charles G. Mullighan

  • The genetic basis of early T-cell precursor acute lymphoblastic leukaemia

    Jinghui Zhang;Li Ding;Linda Holmfeldt;Gang Wu

  • Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia.

    Charles G Mullighan;Xiaoping Su;Jinghui Zhang;Ina Radtke

  • Targetable Kinase-Activating Lesions in Ph-like Acute Lymphoblastic Leukemia

    K. G. Roberts;Y. Li;D. Payne-Turner;R. C. Harvey

  • Improved Survival for Children and Adolescents With Acute Lymphoblastic Leukemia Between 1990 and 2005: A Report From the Children's Oncology Group

    Stephen P. Hunger;Xiaomin Lu;Meenakshi Devidas;Bruce M. Camitta

  • Childhood Acute Lymphoblastic Leukemia: Progress Through Collaboration

    Ching Hon Pui;Jun J. Yang;Stephen P. Hunger;Rob Pieters

  • The genomic landscape of pediatric and young adult T-lineage acute lymphoblastic leukemia

    Yu Liu;John Easton;Ying Shao;Jamie Maciaszek

  • Clinical significance of minimal residual disease in childhood acute lymphoblastic leukemia and its relationship to other prognostic factors: a Children's Oncology Group study.

    Michael J. Borowitz;Meenakshi Devidas;Stephen P. Hunger;W. Paul Bowman;W. Paul Bowman

  • Pan-cancer genome and transcriptome analyses of 1,699 paediatric leukaemias and solid tumours

    Xiaotu Ma;Yu Liu;Yanling Liu;Ludmil B. Alexandrov

  • Genetic Alterations Activating Kinase and Cytokine Receptor Signaling in High-Risk Acute Lymphoblastic Leukemia

    Kathryn G. Roberts;Ryan D. Morin;Jinghui Zhang;Martin Hirst

  • Improved Early Event-Free Survival With Imatinib in Philadelphia Chromosome–Positive Acute Lymphoblastic Leukemia: A Children's Oncology Group Study

    Kirk R. Schultz;W. Paul Bowman;Alexander Aledo;William B. Slayton

  • An Oncogenic Super-Enhancer Formed Through Somatic Mutation of a Noncoding Intergenic Element

    Marc R. Mansour;Marc R. Mansour;Brian J. Abraham;Lars Anders;Alla Berezovskaya

  • The genomic landscape of hypodiploid acute lymphoblastic leukemia

    Linda Holmfeldt;Lei Wei;Ernesto Diaz-Flores;Michael Walsh

  • Rearrangement of CRLF2 is associated with mutation of JAK kinases, alteration of IKZF1, Hispanic/Latino ethnicity, and a poor outcome in pediatric B-progenitor acute lymphoblastic leukemia

    Richard C. Harvey;Richard C. Harvey;Charles G. Mullighan;I-Ming Chen;I-Ming Chen;Walker Wharton

  • JAK mutations in high-risk childhood acute lymphoblastic leukemia.

    Charles G. Mullighan;Jinghui Zhang;Richard C. Harvey;J. Racquel Collins-Underwood

  • Rearrangement of CRLF2 in B-progenitor- and Down syndrome-associated acute lymphoblastic leukemia.

    Charles G Mullighan;J Racquel Collins-Underwood;Letha A A Phillips;Michael G Loudin

  • L-asparaginase treatment in acute lymphoblastic leukemia: a focus on Erwinia asparaginase

    Rob Pieters;Stephen P. Hunger;Joachim Boos;Carmelo Rizzari

  • Factors Influencing Survival After Relapse From Acute Lymphoblastic Leukemia: A Children's Oncology Group Study

    Kim Nguyen;Meenakshi Devidas;Su-Chun Cheng;Mei La

  • Risk- and response-based classification of childhood B-precursor acute lymphoblastic leukemia: a combined analysis of prognostic markers from the Pediatric Oncology Group (POG) and Children's Cancer Group (CCG)

    Kirk R. Schultz;D. Jeanette Pullen;Harland N. Sather;Jonathan J. Shuster

  • Rearrangement of CRLF2 in B-Progenitor and Down Syndrome Associated Acute Lymphoblastic Leukemia.

    Charles G. Mullighan;J. Racquel Collins-Underwood;Letha A Phillips;Michael G. Loudin

Frequent Co-Authors

Meenakshi Devidas
Meenakshi Devidas St. Jude Children's Research Hospital
Mignon L. Loh
Mignon L. Loh University of California, San Francisco
William L. Carroll
William L. Carroll New York University
Naomi J. Winick
Naomi J. Winick The University of Texas Southwestern Medical Center
Elizabeth A. Raetz
Elizabeth A. Raetz New York University
Cheryl L. Willman
Cheryl L. Willman University of New Mexico
Charles G. Mullighan
Charles G. Mullighan St. Jude Children's Research Hospital
Nyla A. Heerema
Nyla A. Heerema The Ohio State University
Michael J. Borowitz
Michael J. Borowitz Johns Hopkins University
Brent L. Wood
Brent L. Wood University of Washington

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