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Genetics

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102
Citations
171822
World Ranking
688
National Ranking
350

Medicine

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102
Citations
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7459
National Ranking
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Overview

Jinghui Zhang is affiliated with St. Jude Children's Research Hospital in the United States and is active in the fields of Medicine and Biochemistry, Genetics, and Molecular Biology. Their research primarily focuses on Molecular Biology, Pediatrics, Perinatology and Child Health, Cancer Research, Public Health, Environmental and Occupational Health, and Genetics.

Their notable research topics include Childhood Cancer Survivors' Quality of Life, Acute Lymphoblastic Leukemia research, Cancer Genomics and Diagnostics, Epigenetics and DNA Methylation, Acute Myeloid Leukemia Research, RNA modifications and cancer, and Genomics and Rare Diseases.

Jinghui Zhang has contributed to various publications, with frequent venues including Cancer Research, bioRxiv (Cold Spring Harbor Laboratory), Blood, Nature Communications, and Cancer Discovery.

Some of their recent published papers are:

  • The genomic landscape of pediatric acute lymphoblastic leukemia, 2022, Nature Genetics
  • Uncovering novel mutational signatures by de novo extraction with SigProfilerExtractor, 2022, Cell Genomics
  • St. Jude Cloud: A Pediatric Cancer Genomic Data-Sharing Ecosystem, 2021, Cancer Discovery
  • Enhancer Hijacking Drives Oncogenic BCL11B Expression in Lineage-Ambiguous Stem Cell Leukemia, 2021, Cancer Discovery
  • Pan-neuroblastoma analysis reveals age- and signature-associated driver alterations, 2020, Nature Communications

Frequent co-authors working alongside Jinghui Zhang include John Easton, Zhaoming Wang, Heather Mulder, Melissa M. Hudson, and Xiaotu Ma.

Best Publications

  • Gapped BLAST and PSI-BLAST: a new generation of protein database search programs.

    Stephen F. Altschul;Thomas L. Madden;Alejandro A. Schäffer;Jinghui Zhang

  • The Sequence of the Human Genome

    J. Craig Venter;Mark D. Adams;Eugene W. Myers;Peter W. Li

  • Comprehensive genomic characterization defines human glioblastoma genes and core pathways

    Roger McLendon;Allan Friedman;Darrell Bigner;Erwin G. Van Meir

  • Genome-wide association study identifies novel breast cancer susceptibility loci

    Douglas F. Easton;Karen A. Pooley;Alison M. Dunning;Paul D. P. Pharoah

  • The genetic basis of early T-cell precursor acute lymphoblastic leukaemia

    Jinghui Zhang;Li Ding;Linda Holmfeldt;Gang Wu

  • Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas

    Gang Wu;Alberto Broniscer;Troy A McEachron;Charles Lu

  • Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia.

    Charles G Mullighan;Xiaoping Su;Jinghui Zhang;Ina Radtke

  • The landscape of genomic alterations across childhood cancers

    Susanne N. Gröbner;Barbara C. Worst;Joachim Weischenfeldt;Joachim Weischenfeldt;Ivo Buchhalter

  • Targetable Kinase-Activating Lesions in Ph-like Acute Lymphoblastic Leukemia

    K. G. Roberts;Y. Li;D. Payne-Turner;R. C. Harvey

  • Germline Mutations in Predisposition Genes in Pediatric Cancer

    Jinghui Zhang;Michael F. Walsh;Gang Wu;Michael N. Edmonson

  • The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma

    Gang Wu;Alexander K Diaz;Alexander K Diaz;Barbara S Paugh;Sherri L Rankin

  • The whole-genome landscape of medulloblastoma subtypes

    Paul A. Northcott;Paul A. Northcott;Ivo Buchhalter;Ivo Buchhalter;A. Sorana Morrissy;Volker Hovestadt

  • The genomic landscape of pediatric and young adult T-lineage acute lymphoblastic leukemia

    Yu Liu;John Easton;Ying Shao;Jamie Maciaszek

  • Novel mutations target distinct subgroups of medulloblastoma

    Giles Robinson;Matthew Parker;Tanya A. Kranenburg;Charles Lu;Charles Lu

  • Pan-cancer genome and transcriptome analyses of 1,699 paediatric leukaemias and solid tumours

    Xiaotu Ma;Yu Liu;Yanling Liu;Ludmil B. Alexandrov

  • Genetic Alterations Activating Kinase and Cytokine Receptor Signaling in High-Risk Acute Lymphoblastic Leukemia

    Kathryn G. Roberts;Ryan D. Morin;Jinghui Zhang;Martin Hirst

  • Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas

    Jinghui Zhang;Gang Wu;Claudia P. Miller;Ruth G. Tatevossian

  • The genomic landscape of hypodiploid acute lymphoblastic leukemia

    Linda Holmfeldt;Lei Wei;Ernesto Diaz-Flores;Michael Walsh

  • JAK mutations in high-risk childhood acute lymphoblastic leukemia.

    Charles G. Mullighan;Jinghui Zhang;Richard C. Harvey;J. Racquel Collins-Underwood

  • Integrated genomic analyses of ovarian carcinoma

    D. Bell;A. Berchuck;M. Birrer;J. Chien

Frequent Co-Authors

James R. Downing
James R. Downing St. Jude Children's Research Hospital
John Easton
John Easton St. Jude Children's Research Hospital
Gang Wu
Gang Wu Washington University in St. Louis
Michael Rusch
Michael Rusch St. Jude Children's Research Hospital
Charles G. Mullighan
Charles G. Mullighan St. Jude Children's Research Hospital
Stephen P. Hunger
Stephen P. Hunger University of Pennsylvania
Ching-Hon Pui
Ching-Hon Pui St. Jude Children's Research Hospital
Mignon L. Loh
Mignon L. Loh University of California, San Francisco
Elaine R. Mardis
Elaine R. Mardis The Ohio State University
Richard K. Wilson
Richard K. Wilson Nationwide Children's Hospital

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