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Genetics
Germany
2024
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Genetics and Molecular Biology
Germany
2024

D-Index & Metrics

Genetics

D-Index
108
Citations
55728
World Ranking
563
National Ranking
45

Research.com Recognitions

  • 2024 - Research.com Genetics in Germany Leader Award
  • 2024 - Research.com Genetics and Molecular Biology in Germany Leader Award
  • 2023 - Research.com Genetics in Germany Leader Award

Overview

Burkhard Rost is affiliated with the Technical University of Munich in Germany and focuses on research mainly within the domain of Biochemistry, Genetics, and Molecular Biology. Their work emphasizes Molecular Biology as the primary subfield, alongside contributions to Genetics, Materials Chemistry, Radiology, Nuclear Medicine and Imaging, and Artificial Intelligence.

The research topics Burkhard Rost has addressed include:

  • Machine Learning in Bioinformatics
  • Genomics and Phylogenetic Studies
  • RNA and protein synthesis mechanisms
  • Protein Structure and Dynamics
  • Bioinformatics and Genomic Networks
  • Genetics, Bioinformatics, and Biomedical Research
  • Enzyme Structure and Function

Several recent publications illustrate the scope of Rost's research output. These include:

  • "ProtTrans: Toward Understanding the Language of Life Through Self-Supervised Learning," 2021, published in IEEE Transactions on Pattern Analysis and Machine Intelligence
  • "PredictProtein - Predicting Protein Structure and Function for 29 Years," 2021, Nucleic Acids Research
  • "ProtTrans: Towards Cracking the Language of Life's Code Through Self-Supervised Deep Learning and High Performance Computing," 2020, arXiv (Cornell University)
  • "Embeddings from deep learning transfer GO annotations beyond homology," 2021, Scientific Reports
  • "Embeddings from protein language models predict conservation and variant effects," 2021, Human Genetics

Burkhard Rost collaborates frequently with other researchers. Notable coauthors include:

  • Michael Heinzinger
  • Christian Dallago
  • Maria Littmann
  • Martin Steinegger
  • Tobias Olenyi

Regarding publication venues, Rost has contributed extensively to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Zenodo (CERN European Organization for Nuclear Research)
  • Scientific Reports
  • arXiv (Cornell University)
  • BMC Bioinformatics

Best Publications

  • The Transcriptional Landscape of the Mammalian Genome

    P. Carninci;T. Kasukawa;S. Katayama;J. Gough

  • Prediction of protein secondary structure at better than 70% accuracy.

    Burkhard Rost;Chris Sander

  • Twilight zone of protein sequence alignments.

    Burkhard Rost

  • Combining evolutionary information and neural networks to predict protein secondary structure.

    Burkhard Rost;Chris Sander

  • The PredictProtein server

    Burkhard Rost;Guy Yachdav;Jinfeng Liu

  • PHD: predicting one-dimensional protein structure by profile-based neural networks.

    Burkhard Rost

  • A large-scale evaluation of computational protein function prediction

    Predrag Radivojac;Wyatt T Clark;Tal Ronnen Oron;Alexandra M Schnoes

  • A Mutation in VPS35, Encoding a Subunit of the Retromer Complex, Causes Late-Onset Parkinson Disease

    Alexander Zimprich;Anna Benet-Pagès;Walter Struhal;Elisabeth Graf

  • Improving the prediction of protein secondary structure in three and eight classes using recurrent neural networks and profiles.

    Gianluca Pollastri;Darisz Przybylski;Burkhard Rost;Pierre Baldi

  • SNAP: predict effect of non-synonymous polymorphisms on function

    Yana Bromberg;Burkhard Rost

  • Topology prediction for helical transmembrane proteins at 86% accuracy.

    Burkhard Rost;Piero Fariselli;Rita Casadio

  • PHD - AN AUTOMATIC MAIL SERVER FOR PROTEIN SECONDARY STRUCTURE PREDICTION

    Burkhard Rost;Chris Sander;Reinhard Schneider

  • Finding nuclear localization signals.

    Murat Cokol;Rajesh Nair;Burkhard Rost

  • Conservation and prediction of solvent accessibility in protein families

    Burkhard Rost;Chris Sander

  • Review: protein secondary structure prediction continues to rise.

    Burkhard Rost

  • A draft network of ligand–receptor-mediated multicellular signalling in human

    Jordan A. Ramilowski;Tatyana Goldberg;Jayson Harshbarger;Edda Kloppmann

  • Improved prediction of protein secondary structure by use of sequence profiles and neural networks

    Burkhard Rost;Chris Sander

  • Transmembrane helices predicted at 95% accuracy

    Burkhard Rost;Rita Casadio;Piero Fariselli;Chris Sander

  • PredictProtein—an open resource for online prediction of protein structural and functional features

    Guy Yachdav;Edda Kloppmann;Laszlo Kajan;Maximilian Hecht

  • Three-dimensional structures of membrane proteins from genomic sequencing.

    Thomas A. Hopf;Lucy J. Colwell;Robert Sheridan;Burkhard Rost

Frequent Co-Authors

Gaetano T. Montelione
Gaetano T. Montelione Rensselaer Polytechnic Institute
Rong Xiao
Rong Xiao Rutgers, The State University of New Jersey
Jinfeng Liu
Jinfeng Liu Genentech
Chris Sander
Chris Sander Harvard University
Thomas Szyperski
Thomas Szyperski University at Buffalo, State University of New York
James H. Prestegard
James H. Prestegard University of Georgia
Michal Linial
Michal Linial Hebrew University of Jerusalem
Christine A. Orengo
Christine A. Orengo University College London
Reinhard Schneider
Reinhard Schneider University of Luxembourg
David T. Jones
David T. Jones University College London

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