World's Best Scientists 2026 revealed!

D-Index & Metrics

Engineering and Technology

D-Index
66
Citations
21699
World Ranking
1379
National Ranking
34

Biology and Biochemistry

D-Index
73
Citations
25953
World Ranking
5826
National Ranking
131

Overview

Rita Casadio is affiliated with the University of Bologna in Italy and has a research focus primarily within the fields of Biochemistry, Genetics, and Molecular Biology. The subfields of study associated with their work include Molecular Biology, Genetics, Cancer Research, Materials Chemistry, and Clinical Biochemistry.

The main topics of Casadio's research encompass Machine Learning in Bioinformatics, Genomics and Phylogenetic Studies, Protein Structure and Dynamics, RNA and Protein Synthesis Mechanisms, Genomics and Rare Diseases, Bioinformatics and Genomic Networks, and Genetics, Bioinformatics, and Biomedical Research.

Frequent coauthors collaborating with Casadio include Pier Luigi Martelli, Castrense Savojardo, Giulia Babbi, Matteo Manfredi, and Steven E. Brenner.

Casadio has published research in several prominent venues over their career, including Journal of Molecular Biology, Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature, Human Genetics, bioRxiv (Cold Spring Harbor Laboratory), and Faculty of 1000 Research Ltd.

Some of Casadio's recent papers are:

  • "DOME: recommendations for supervised machine learning validation in biology," 2021, Archivio Istituzionale della Ricerca (Universita Degli Studi Di Milano)
  • "Solvent Accessibility of Residues Undergoing Pathogenic Variations in Humans: From Protein Structures to Protein Sequences," 2021, Frontiers in Molecular Biosciences
  • "Machine learning solutions for predicting protein-protein interactions," 2022, Wiley Interdisciplinary Reviews Computational Molecular Science
  • "CAGI, the Critical Assessment of Genome Interpretation, establishes progress and prospects for computational genetic variant interpretation methods," 2024, Genome Biology
  • "Biallelic variants in LIG3 cause a novel mitochondrial neurogastrointestinal encephalomyopathy," 2021, Brain

Best Publications

  • I-Mutant2.0: predicting stability changes upon mutation from the protein sequence or structure.

    Emidio Capriotti;Piero Fariselli;Rita Casadio

  • Transglutaminases: Nature’s biological glues

    Martin Griffin;Rita Casadio;Carlo M Bergamini

  • A large-scale evaluation of computational protein function prediction

    Predrag Radivojac;Wyatt T Clark;Tal Ronnen Oron;Alexandra M Schnoes

  • Predicting the insurgence of human genetic diseases associated to single point protein mutations with support vector machines and evolutionary information

    E. Capriotti;R. Calabrese;R. Casadio

  • Topology prediction for helical transmembrane proteins at 86% accuracy.

    Burkhard Rost;Piero Fariselli;Rita Casadio

  • Functional annotations improve the predictive score of human disease-related mutations in proteins

    Remo Calabrese;Emidio Capriotti;Piero Fariselli;Pier Luigi Martelli

  • PredGPI: a GPI-anchor predictor

    Andrea Pierleoni;Pier Luigi Martelli;Rita Casadio

  • Transmembrane helices predicted at 95% accuracy

    Burkhard Rost;Rita Casadio;Piero Fariselli;Chris Sander

  • ConSeq: the identification of functionally and structurally important residues in protein sequences

    Carine Berezin;Fabian Glaser;Josef Rosenberg;Inbal Paz

  • Algorithms in Bioinformatics

    Rita Casadio;Gene Myers

  • An expanded evaluation of protein function prediction methods shows an improvement in accuracy

    Yuxiang Jiang;Tal Ronnen Oron;Wyatt T. Clark;Asma R. Bankapur

  • The CAFA challenge reports improved protein function prediction and new functional annotations for hundreds of genes through experimental screens

    Naihui Zhou;Yuxiang Jiang;Timothy R. Bergquist;Alexandra J. Lee

  • BUSCA: an integrative web server to predict subcellular localization of proteins.

    Castrense Savojardo;Pier Luigi Martelli;Piero Fariselli;Giuseppe Profiti;Giuseppe Profiti

  • BaCelLo: a Balanced subCellular Localization predictor.

    Andrea Pierleoni;Pier Luigi Martelli;Piero Fariselli;Rita Casadio

  • WS-SNPs&GO: a web server for predicting the deleterious effect of human protein variants using functional annotation

    Emidio Capriotti;Remo Calabrese;Piero Fariselli;Pier Luigi Martelli

  • Prediction of protein--protein interaction sites in heterocomplexes with neural networks.

    Piero Fariselli;Florencio Pazos;Alfonso Valencia;Rita Casadio

  • A three-state prediction of single point mutations on protein stability changes

    Emidio Capriotti;Piero Fariselli;Ivan Rossi;Rita Casadio

  • Prediction of coordination number and relative solvent accessibility in proteins.

    Gianluca Pollastri;Pierre Baldi;Pietro Fariselli;Rita Casadio

  • A high‐density, SNP‐based consensus map of tetraploid wheat as a bridge to integrate durum and bread wheat genomics and breeding

    Marco Maccaferri;Andrea Ricci;Silvio Salvi;Sara Giulia Milner

  • An expanded evaluation of protein function prediction methods shows an improvement in accuracy

    Yuxiang Jiang;Tal Ronnen Oron;Wyatt T Clark;Asma R Bankapur

  • Additional file 1 of An expanded evaluation of protein function prediction methods shows an improvement in accuracy

    Yuxiang Jiang;Tal Ronnen Oron;Wyatt T. Clark;Asma R. Bankapur

Frequent Co-Authors

Piero Fariselli
Piero Fariselli University of Turin
Luca Fontanesi
Luca Fontanesi University of Bologna
David T. Jones
David T. Jones University College London
Olivier Lichtarge
Olivier Lichtarge Baylor College of Medicine
Predrag Radivojac
Predrag Radivojac Northeastern University
Steven E. Brenner
Steven E. Brenner University of California, Berkeley
Vincenzo Russo
Vincenzo Russo University of Bologna
Sean D. Mooney
Sean D. Mooney University of Washington
Alfonso Valencia
Alfonso Valencia Barcelona Supercomputing Center
Silvio C. E. Tosatto
Silvio C. E. Tosatto University of Padua

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