D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 50 Citations 12,016 118 World Ranking 12955 National Ranking 202

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • Enzyme
  • Biochemistry

Her main research concerns Heparan sulfate, Biochemistry, Molecular biology, Cell biology and Heparan Sulfate Biosynthesis. Her Heparan sulfate research is multidisciplinary, incorporating elements of Proteoglycan, Membrane and Chromatography. Her biological study spans a wide range of topics, including In vivo, Kidney, Percoll and Glucosamine.

Her Cell biology study integrates concerns from other disciplines, such as Angiogenesis and Transactivation. Lena Kjellén has included themes like Perlecan and Biosynthesis in her Heparan Sulfate Biosynthesis study. Her Sulfation research incorporates themes from Mast cell and Extracellular matrix.

Her most cited work include:

  • Proteoglycans: structures and interactions. (1668 citations)
  • Regulated diversity of heparan sulfate. (606 citations)
  • Abnormal mast cells in mice deficient in a heparin-synthesizing enzyme (419 citations)

What are the main themes of her work throughout her whole career to date?

Her primary areas of study are Heparan sulfate, Biochemistry, Sulfation, Cell biology and Enzyme. Her Heparan sulfate research incorporates elements of Molecular biology, Endocrinology and Sulfotransferase. Biosynthesis, Heparin, Glycosaminoglycan, Polysaccharide and Glucosamine are subfields of Biochemistry in which her conducts study.

Lena Kjellén combines subjects such as HEK 293 cells, Cell culture, Receptor, Plasma protein binding and Golgi apparatus with her study of Sulfation. Her Cell biology research includes themes of Mast cell, Embryonic stem cell, Angiogenesis and Cell type. Her Enzyme research is multidisciplinary, incorporating perspectives in Internal medicine and Mutant.

She most often published in these fields:

  • Heparan sulfate (58.59%)
  • Biochemistry (57.81%)
  • Sulfation (29.69%)

What were the highlights of her more recent work (between 2010-2021)?

  • Heparan sulfate (58.59%)
  • Biochemistry (57.81%)
  • Cell biology (28.91%)

In recent papers she was focusing on the following fields of study:

Heparan sulfate, Biochemistry, Cell biology, Chondroitin sulfate and Sulfation are her primary areas of study. Her research on Heparan sulfate focuses in particular on Heparan Sulfate Biosynthesis. Her study in Heparin, Perlecan, Sulfotransferase, Enzyme and Cell is carried out as part of her studies in Biochemistry.

Her Cell biology research integrates issues from Proteases, Chymase and Tryptase. Her research in Chondroitin sulfate intersects with topics in Proteoglycan, Extracellular matrix, Mast cell and Chondroitin. Her work carried out in the field of Sulfation brings together such families of science as Plasma protein binding and Zebrafish.

Between 2010 and 2021, her most popular works were:

  • Heparan sulfate biosynthesis: regulation and variability. (162 citations)
  • Pathophysiology of heparan sulphate: many diseases, few drugs (126 citations)
  • Mast Cell Chymase Degrades the Alarmins Heat Shock Protein 70, Biglycan, HMGB1, and Interleukin-33 (IL-33) and Limits Danger-induced Inflammation * (88 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Biochemistry

Her primary areas of investigation include Biochemistry, Heparan sulfate, Heparin, Heparan Sulfate Biosynthesis and Sulfation. Her research integrates issues of Inflammation and Mast cell in her study of Biochemistry. Her Heparan sulfate study contributes to a more complete understanding of Glycosaminoglycan.

Her Heparin study combines topics in areas such as Protein ligand, Plasma protein binding and Protein–protein interaction. The Cell study combines topics in areas such as Transcription, Homeostasis and Biosynthesis. The study incorporates disciplines such as Enzyme complex and Sulfotransferase in addition to Molecular biology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Proteoglycans: structures and interactions.

Lena Kjellén;Ulf Lindahl.
Annual Review of Biochemistry (1991)

2522 Citations

Regulated diversity of heparan sulfate.

Ulf Lindahl;Marion Kusche-Gullberg;Lena Kjellén.
Journal of Biological Chemistry (1998)

872 Citations

Abnormal mast cells in mice deficient in a heparin-synthesizing enzyme

Erik Forsberg;Gunnar Pejler;Maria Ringvall;Carolina Lunderius.
Nature (1999)

552 Citations

More to “heparin” than anticoagulation

Ulf Lindahl;Kerstin Lidholt;Dorothe Spillmann;Lena Kjellén.
Thrombosis Research (1994)

457 Citations

Sulfotransferases in glycosaminoglycan biosynthesis.

Marion Kusche-Gullberg;Lena Kjellén.
Current Opinion in Structural Biology (2003)

376 Citations

Heparan Sulfate Structure in Mice with Genetically Modified Heparan Sulfate Production

Johan Ledin;William Staatz;Jin Ping Li;Martin Götte.
Journal of Biological Chemistry (2004)

293 Citations

Heparan sulfate in trans potentiates VEGFR-mediated angiogenesis.

Lars Jakobsson;Johan Kreuger;Katarina Holmborn;Lars Lundin.
Developmental Cell (2006)

287 Citations

Defective Heparan Sulfate Biosynthesis and Neonatal Lethality in Mice LackingN-Deacetylase/N-Sulfotransferase-1

Maria Ringvall;Johan Ledin;Katarina Holmborn;Toin van Kuppevelt.
Journal of Biological Chemistry (2000)

283 Citations

The viability of cells grown or centrifuged in a new density gradient medium, Percoll(TM).

Håkan Pertoft;Kristofer Rubin;Lena Kjellén;Torvard C. Laurent.
Experimental Cell Research (1977)

276 Citations

Cell-surface heparan sulfate. Mechanisms of proteoglycan-cell association.

L Kjellén;A Oldberg;M Höök.
Journal of Biological Chemistry (1980)

271 Citations

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