Koji Kimata mainly investigates Biochemistry, Molecular biology, Heparan sulfate, Proteoglycan and Cell biology. Many of his studies on Biochemistry involve topics that are commonly interrelated, such as Hyaluronic acid. His Molecular biology research is multidisciplinary, relying on both Complementary DNA, Locus and HAS1, Hyaluronan synthase.
His study in Heparan sulfate is interdisciplinary in nature, drawing from both Sulfation, Sulfotransferase, Immunostaining and Fibroblast growth factor. Koji Kimata has included themes like Pathology and Choroid plexus in his Proteoglycan study. In the subject of general Cell biology, his work in Extracellular matrix is often linked to Aggrecan, thereby combining diverse domains of study.
Biochemistry, Molecular biology, Heparan sulfate, Cell biology and Chondroitin sulfate are his primary areas of study. His study in Sulfation, Glycosaminoglycan, Proteoglycan, Chondroitin and Sulfotransferase falls under the purview of Biochemistry. His study in the fields of Versican under the domain of Proteoglycan overlaps with other disciplines such as Aggrecan.
His work is dedicated to discovering how Molecular biology, Complementary DNA are connected with Peptide sequence and other disciplines. The Heparan sulfate study combines topics in areas such as Signal transduction and Fibroblast growth factor. He studied Chondroitin sulfate and Stereochemistry that intersect with Residue.
His primary scientific interests are in Biochemistry, Extracellular matrix, Chondroitin sulfate, Cell biology and Pathology. His research links Mast cell with Biochemistry. His Versican and Proteoglycan study in the realm of Extracellular matrix interacts with subjects such as Vascular smooth muscle and Bone Wires.
His Chondroitin sulfate research includes elements of Wild type, Chondrocyte, Glycosyltransferase and Chondroitin. The study incorporates disciplines such as Chemokine, Cell and Immunology in addition to Cell biology. His Pathology research is multidisciplinary, incorporating perspectives in Cancer research, Cell growth, Internal medicine, Metastasis and In vivo.
Koji Kimata mostly deals with Cell biology, Extracellular matrix, Sulfation, Glycosaminoglycan and Biochemistry. His study in the field of Versican also crosses realms of Histidine decarboxylase. The concepts of his Extracellular matrix study are interwoven with issues in CD44 and Hyaluronic acid.
His work carried out in the field of Sulfation brings together such families of science as Heparan sulfate and Chondroitin sulfate. His work focuses on many connections between Glycosaminoglycan and other disciplines, such as Extracellular, that overlap with his field of interest in Mesenchymal stem cell, Chondroitin sulfate proteoglycan and Proteoglycan. His work on Biochemistry is being expanded to include thematically relevant topics such as Histamine.
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Three Isoforms of Mammalian Hyaluronan Synthases Have Distinct Enzymatic Properties
Naoki Itano;Takahiro Sawai;Mamoru Yoshida;Petros Lenas.
Journal of Biological Chemistry (1999)
Characterization of fibronectin interactions with glycosaminoglycans and identification of active proteolytic fragments.
K M Yamada;D W Kennedy;K Kimata;R M Pratt.
Journal of Biological Chemistry (1980)
A chondrogenic cell line derived from a differentiating culture of AT805 teratocarcinoma cells.
Tadao Atsumi;Yoji Ikawa;Yoko Miwa;Koji Kimata.
Mechanisms of Development (1990)
The presence of heparan sulfate proteoglycans in the neuritic plaques and congophilic angiopathy in Alzheimer's disease.
A. D. Snow;H. Mar;D. Nochlin;K. Kimata.
American Journal of Pathology (1988)
An important role of heparan sulfate proteoglycan (perlecan) in a model system for the deposition and persistence of fibrillar aβ-amyloid in rat brain
Alan D. Snow;Raymond Sekiguchi;David Nochlin;Paul Fraser.
Neuron (1994)
Mammalian hyaluronan synthases.
Naoki Itano;Koji Kimata.
Iubmb Life (2002)
Proteoglycans and Sulfated Glycosaminoglycans
Ulf Lindahl;John Couchman;Koji Kimata;Jeffrey D. Esko.
Edition:3rd (2009)
Abnormal accumulation of hyaluronan matrix diminishes contact inhibition of cell growth and promotes cell migration.
Naoki Itano;Fukiko Atsumi;Takahiro Sawai;Yoichi Yamada.
Proceedings of the National Academy of Sciences of the United States of America (2002)
Roles of Aggrecan, a Large Chondroitin Sulfate Proteoglycan, in Cartilage Structure and Function
Hideto Watanabe;Yoshihiko Yamada;Koji Kimata.
Journal of Biochemistry (1998)
Characterization of growth factor-binding structures in heparin/heparan sulfate using an octasaccharide library.
Satoko Ashikari-Hada;Hiroko Habuchi;Yutaka Kariya;Nobuyuki Itoh.
Journal of Biological Chemistry (2004)
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