2026 Yoshihiko Yamada: Biology and Biochemistry Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Biology and Biochemistry	99	1597	1441	895	791	348	33401

Overview

Yoshihiko Yamada is affiliated with the National Institutes of Health in the United States and has contributed extensively to the fields of Medicine and Biochemistry, Genetics, and Molecular Biology. Their research spans multiple subfields including Molecular Biology, Neurology, Pulmonary and Respiratory Medicine, Surgery, and Epidemiology.

Their work has covered various main research topics, such as:

Intracranial Aneurysms: Treatment and Complications
Prostate Cancer Diagnosis and Treatment
Pluripotent Stem Cells Research
Trigeminal Neuralgia and Treatments
Cerebrovascular and Carotid Artery Diseases
Epigenetics and DNA Methylation
Prostate Cancer Treatment and Research

Yamada has published in a variety of scientific venues, frequently contributing to:

Asian Journal of Neurosurgery
Scientific Reports
Nature Communications
arXiv (Cornell University)
Communications Biology

Notable recent papers include:

"Generation of a p16 Reporter Mouse and Its Use to Characterize and Target p16high Cells In Vivo" (2020), published in Cell Metabolism
"Identification of distinct loci for de novo DNA methylation by DNMT3A and DNMT3B during mammalian development" (2020), published in Nature Communications
"Induced pluripotent stem cell-derived tenocyte-like cells promote the regeneration of injured tendons in mice" (2020), published in Scientific Reports
"DMRT1-mediated reprogramming drives development of cancer resembling human germ cell tumors with features of totipotency" (2021), published in Nature Communications
"TGF-β-dependent reprogramming of amino acid metabolism induces epithelial-mesenchymal transition in non-small cell lung cancers" (2021), published in Communications Biology

Yamada collaborates frequently with several co-authors, including:

Yoko Kato
Riki Tanaka
Kento Sasaki
Manabu Ozawa
Tsukasa Kawase

Best Publications

Two different laminin domains mediate the differentiation of human endothelial cells into capillary-like structures in vitro

Derrick S. Grant;Ken-Ichiro Tashiro;Bartolome Segui-Real;Yoshihiko Yamada

1101
Citations
A simplified laminin nomenclature

Monique Aumailley;Leena Bruckner-Tuderman;William G. Carter;Rainer Deutzmann

1088
Citations
Identification of an amino acid sequence in laminin mediating cell attachment, chemotaxis, and receptor binding.

Jeannette Graf;Yukihide Iwamoto;Makoto Sasaki;George R. Martin

982
Citations
A new nomenclature for the laminins.

Robert E. Burgeson;Matthias Chiquet;Rainer Deutzmann;Peter Ekblom

927
Citations
YIGSR, a synthetic laminin pentapeptide, inhibits experimental metastasis formation.

Yukihide Iwamoto;Frank A. Robey;Jeannette Graf;Makoto Sasaki

825
Citations
Perlecan is essential for cartilage and cephalic development

Eri Arikawa-Hirasawa;Hideto Watanabe;Hiroya Takami;John R. Hassell

739
Citations
The complete sequence of perlecan, a basement membrane heparan sulfate proteoglycan, reveals extensive similarity with laminin A chain, low density lipoprotein-receptor, and the neural cell adhesion molecule.

Douglas M. Noonan;Anna Fulle;Piera Valente;Silla Cai

628
Citations
A pentapeptide from the laminin B1 chain mediates cell adhesion and binds the 67,000 laminin receptor.

Jeannette Graf;Roy C. Ogle;Frank A. Robey;Makoto Sasaki

620
Citations
SOX9 enhances aggrecan gene promoter/enhancer activity and is up-regulated by retinoic acid in a cartilage-derived cell line, TC6.

Ichiro Sekiya;Kunikazu Tsuji;Peter Koopman;Hideto Watanabe

605
Citations
Sequence of the cDNA encoding the laminin B1 chain reveals a multidomain protein containing cysteine-rich repeats

Makoto Sasaki;Seishi Kato;Kimitoshi Kohno;George R. Martin

517
Citations
Regulated recruitment of HP1 to a euchromatic gene induces mitotically heritable, epigenetic gene silencing: a mammalian cell culture model of gene variegation

Kasirajan Ayyanathan;Mark S. Lechner;Peter Bell;Gerd G. Maul

515
Citations
Receptor-specific increase in extracellular matrix production in mouse mesangial cells by advanced glycosylation end products is mediated via platelet-derived growth factor.

Toshio Doi;Helen Vlassara;Martina Kirstein;Yoshihiko Yamada

501
Citations
Roles of Aggrecan, a Large Chondroitin Sulfate Proteoglycan, in Cartilage Structure and Function

Hideto Watanabe;Yoshihiko Yamada;Koji Kimata

439
Citations
Ameloblastin is a cell adhesion molecule required for maintaining the differentiation state of ameloblasts.

Satoshi Fukumoto;Takayoshi Kiba;Bradford Hall;Noriyuki Iehara

418
Citations
Developmental Regulation of Wnt/β-Catenin Signals Is Required for Growth Plate Assembly, Cartilage Integrity, and Endochondral Ossification

Yoshihiro Tamamura;Tomohiro Otani;Naoko Kanatani;Eiki Koyama

409
Citations
Transcriptional Cross-talk between Smad, ERK1/2, and p38 Mitogen-activated Protein Kinase Pathways Regulates Transforming Growth Factor-β-induced Aggrecan Gene Expression in Chondrogenic ATDC5 Cells

Hideto Watanabe;Mark P. de Caestecker;Yoshihiko Yamada

396
Citations
A single EGF-like motif of laminin is responsible for high affinity nidogen binding.

U Mayer;R Nischt;E Pöschl;K Mann

387
Citations
Identification of cell binding sites in the laminin α1 chain carboxyl- terminal globular domain by systematic screening of synthetic peptides

Motoyoshi Nomizu;Woo Ho Kim;Keizo Yamamura;Atsushi Utani

372
Citations
Scavenger receptor family proteins: roles for atherosclerosis, host defence and disorders of the central nervous system.

Y Yamada;T Doi;T Hamakubo;T Kodama

371
Citations
Regulatory role of transforming growth factor-beta, bone morphogenetic protein-2, and protein-4 on gene expression of extracellular matrix proteins and differentiation of dental pulp cells.

M Nakashima;H Nagasawa;Y Yamada;A H Reddi

365
Citations