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Biology and Biochemistry

D-Index
65
Citations
13044
World Ranking
9292
National Ranking
626

Overview

Motoyoshi Nomizu is affiliated with Tokyo University of Pharmacy and Life Sciences in Japan. Their research spans multiple disciplines, focusing primarily on biochemistry, genetics, molecular biology, and medicine. Within these broader fields, the scientist addresses a number of subfields including molecular biology, immunology and allergy, cell biology, cancer research, and biomaterials.

Their work concentrates on several main research topics, such as cell adhesion molecules research, RNA interference and gene delivery, cellular mechanics and interactions, protease and inhibitor mechanisms, ultrasound and hyperthermia applications, monoclonal and polyclonal antibodies research, and muscle physiology and disorders.

Motoyoshi Nomizu has published extensively in various scientific venues. Some frequent publication venues include:

  • Glia
  • The FASEB Journal
  • Biological and Pharmaceutical Bulletin
  • ACS Omega
  • Biomacromolecules

The scientist collaborates regularly with several coauthors. Frequent collaborators include:

  • Yamato Kikkawa
  • Keisuke Hamada
  • Yuji Yamada
  • Yoichi Negishi
  • Yoko Endo-Takahashi

Recent publications by Motoyoshi Nomizu highlight various aspects of their research interests. Selected recent papers include:

  • "Structure-Activity Relationships of RGD-Containing Peptides in Integrin αvβ5-Mediated Cell Adhesion" (2023), published in ACS Omega
  • "Development of Three-Dimensional Cell Culture Scaffolds Using Laminin Peptide-Conjugated Agarose Microgels" (2020), published in Biomacromolecules
  • "Ternary Complexes of pDNA, Neuron-Binding Peptide, and PEGylated Polyethyleneimine for Brain Delivery with Nano-Bubbles and Ultrasound" (2021), published in Pharmaceutics
  • "Development of a bispecific DNA-aptamer-based lysosome-targeting chimera for HER2 protein degradation" (2023), published in Cell Reports Physical Science
  • "Alpha-dystroglycan binding peptide A2G80-modified stealth liposomes as a muscle-targeting carrier for Duchenne muscular dystrophy" (2020), published in Journal of Controlled Release

Best Publications

  • The short amino acid sequence Pro-His-Ser-Arg-Asn in human fibronectin enhances cell-adhesive function.

    S.-I. Aota;M. Nomizu;K. M. Yamada

  • Interaction of arginine-rich peptides with membrane-associated proteoglycans is crucial for induction of actin organization and macropinocytosis.

    Ikuhiko Nakase;Akiko Tadokoro;Noriko Kawabata;Toshihide Takeuchi

  • Identification of cell binding sites in the laminin α1 chain carboxyl- terminal globular domain by systematic screening of synthetic peptides

    Motoyoshi Nomizu;Woo Ho Kim;Keizo Yamamura;Atsushi Utani

  • Activation of β1 Integrin Signaling Stimulates Tyrosine Phosphorylation of p190 RhoGAP and Membrane-protrusive Activities at Invadopodia

    Hirokazu Nakahara;Susette C. Mueller;Motoyoshi Nomizu;Yoshihiko Yamada

  • Identification of laminin α1 and β1 chain peptides active for endothelial cell adhesion, tube formation, and aortic sprouting

    Katherine M. Malinda;Motoyoshi Nomizu;Motoyoshi Nomizu;Melissa Chung;Mucio Delgado

  • Laminin-1 and Laminin-2 G-domain Synthetic Peptides Bind Syndecan-1 and Are Involved in Acinar Formation of a Human Submandibular Gland Cell Line

    Matthew P. Hoffman;Motoyoshi Nomizu;Eva Roque;Sharon Lee

  • Nonhydrolyzable Phosphotyrosyl Mimetics for the Preparation Of Phosphatase-Resistant SH2 Domain Inhibitors

    Terrence R. Jr. Burke;Mark S. Smyth;Akira Otaka;Motoyoshi Nomizu

  • Preparation of fluoro- and hydroxy-4-(phosphonomethyl)-D,L-phenylalanine suitably protected for solid-phase synthesis of peptides containing hydrolytically stable analogs of O-phosphotyrosine

    Terrence R. Burke;Mark S. Smyth;Motoyoshi Nomizu;Akira Otaka

  • Cell Binding Sequences in Mouse Laminin α1 Chain

    Motoyoshi Nomizu;Yuichiro Kuratomi;Katherine M. Malinda;Sang-Yong Song

  • A Unique Sequence of the Laminin α3 G Domain Binds to Heparin and Promotes Cell Adhesion through Syndecan-2 and -4

    Atsushi Utani;Motoyoshi Nomizu;Hiroshi Matsuura;Kozue Kato

  • A Mechanism for Regulation of Melanoma Invasion: LIGATION OF α6β1 INTEGRIN BY LAMININ G PEPTIDES

    Hirokazu Nakahara;Motoyoshi Nomizu;Steven K. Akiyama;Yoshihiko Yamada

  • Identification of Cell Binding Sequences in Mouse Laminin γ1 Chain by Systematic Peptide Screening

    Motoyoshi Nomizu;Yuichiro Kuratomi;Sang-Yong Song;M. Lourdes Ponce

  • Functional sites in the laminin alpha chains.

    Nobuharu Suzuki;Fumiharu Yokoyama;Motoyoshi Nomizu

  • Cell Type-specific Differences in Glycosaminoglycans Modulate the Biological Activity of a Heparin-binding Peptide (RKRLQVQLSIRT) from the G Domain of the Laminin α1 Chain

    Matthew P. Hoffman;Jean A. Engbring;Peter K. Nielsen;John Vargas

  • Putative precursors of endothelin have less vasoconstrictor activity in vitro but a potent pressor effect in vivo.

    Tomoko Kashiwabara;Yoshimasa Inagaki;Hideo Ohta;Akihiro Iwamatsu

  • Identification of endothelial cell binding sites on the laminin γ1 chain

    M. Lourdes Ponce;Motoyoshi Nomizu;Mucio C. Delgado;Yuichiro Kuratomi

  • Structure‐activity study of a laminin α1 chain active peptide segment Ile‐Lys‐Val‐Ala‐Val (IKVAV)

    Motoyoshi Nomizu;Benjamin S. Weeks;Christi A. Weston;Woo Hoo Kim

  • Laminin-1 peptide-conjugated chitosan membranes as a novel approach for cell engineering.

    Mayumi Mochizuki;Yuichi Kadoya;Yoko Wakabayashi;Kozue Kato

  • Laminin-111-derived peptides and cancer

    Yamato Kikkawa;Kentaro Hozumi;Fumihiko Katagiri;Motoyoshi Nomizu

  • Identification of Synthetic Peptides Derived from Laminin α1 and α2 Chains with Cell Type Specificity for Neurite Outgrowth

    Barbara L. Richard;Motoyoshi Nomizu;Yoshihiko Yamada;Hynda K. Kleinman

Frequent Co-Authors

Norio Nishi
Norio Nishi Hokkaido University
Yoshihiko Yamada
Yoshihiko Yamada National Institutes of Health
Hynda K. Kleinman
Hynda K. Kleinman George Washington University
Akira Otaka
Akira Otaka University of Tokushima
Peter P. Roller
Peter P. Roller National Institutes of Health
Nobutaka Fujii
Nobutaka Fujii Kyoto University
Terrence R. Burke
Terrence R. Burke National Institutes of Health
Matthew P. Hoffman
Matthew P. Hoffman National Institutes of Health
Toshiyuki Yoneda
Toshiyuki Yoneda Osaka University
Changsheng Zhao
Changsheng Zhao Sichuan University

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