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Chemistry

D-Index
73
Citations
17181
World Ranking
5038
National Ranking
1568

Biology and Biochemistry

D-Index
74
Citations
17394
World Ranking
5677
National Ranking
2690

Overview

Terrence R. Burke is affiliated with the National Institutes of Health in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with significant contributions to subfields such as Molecular Biology, Infectious Diseases, Virology, Organic Chemistry, and Cell Biology.

The scientist's work encompasses a variety of main topics, including:

  • HIV/AIDS drug development and treatment
  • HIV Research and Treatment
  • Biochemical and Molecular Research
  • Cancer therapeutics and mechanisms
  • Ubiquitin and proteasome pathways
  • Microtubule and mitosis dynamics
  • Phenothiazines and Benzothiazines Synthesis and Activities

Some of the recent published papers by Terrence R. Burke and collaborators include:

  • Structural basis for strand-transfer inhibitor binding to HIV intasomes, 2020, Science
  • Integrase Strand Transfer Inhibitors Are Effective Anti-HIV Drugs, 2021, Viruses
  • Chemically Programmable and Switchable CAR-T Therapy, 2020, Angewandte Chemie International Edition
  • Small molecule microarray identifies inhibitors of tyrosyl-DNA phosphodiesterase 1 that simultaneously access the catalytic pocket and two substrate binding sites, 2021, Chemical Science
  • HIV-1 Integrase Inhibitors That Are Active against Drug-Resistant Integrase Mutants, 2020, Antimicrobial Agents and Chemotherapy

Terrence R. Burke often publishes in the following venues:

  • Viruses
  • RSC Chemical Biology
  • Current Medicinal Chemistry
  • Nature Communications
  • ACS Infectious Diseases

Frequent co-authors include:

  • Xue Zhi Zhao
  • Steven J. Smith
  • Stephen H. Hughes
  • Dmitry Lyumkis
  • Kohei Tsuji

Best Publications

  • Caffeic acid phenethyl ester is a potent and specific inhibitor of activation of nuclear transcription factor NF-kappa B

    K. Natarajan;Sanjaya Singh;Terrence R. Burke;Dezider Grunberger

  • Folliculin encoded by the BHD gene interacts with a binding protein, FNIP1, and AMPK, and is involved in AMPK and mTOR signaling

    Masaya Baba;Seung-Beom Hong;Nirmala Sharma;Michelle B. Warren

  • Coumarin-based inhibitors of HIV integrase.

    He Zhao;Nouri Neamati;Huixiao Hong;Abhijit Mazumder

  • Syp (SH-PTP2) is a positive mediator of growth factor-stimulated mitogenic signal transduction.

    Sen Xiao;D. W. Rose;T. Sasaoka;H. Maegawa

  • Potent Inhibition of Insulin Receptor Dephosphorylation by a Hexamer Peptide Containing the Phosphotyrosyl Mimetic F2Pmp

    T.R. Burke;H.K. Kole;P.P. Roller

  • Retroviral DNA integration: reaction pathway and critical intermediates.

    Min Li;Michiyo Mizuuchi;Terrence R Burke;Robert Craigie

  • Hydroxylated aromatic inhibitors of HIV-1 integrase.

    T. R. Burke;M. R. Fesen;Abhijit Mazumder;Jian Wang

  • Grb2 signaling in cell motility and cancer.

    Alessio Giubellino;Terrence R Burke;Donald P Bottaro

  • Structure activity of 3-aryl-1,3-diketo-containing compounds as HIV-1 integrase inhibitors.

    Godwin C. G. Pais;Xuechun Zhang;Christophe Marchand;Nouri Neamati

  • Protein-tyrosine phosphatases: structure, mechanism, and inhibitor discovery.

    Terrence R. Burke;Zhong Yin Zhang

  • Nonhydrolyzable Phosphotyrosyl Mimetics for the Preparation Of Phosphatase-Resistant SH2 Domain Inhibitors

    Terrence R. Jr. Burke;Mark S. Smyth;Akira Otaka;Motoyoshi Nomizu

  • Preparation of fluoro- and hydroxy-4-(phosphonomethyl)-D,L-phenylalanine suitably protected for solid-phase synthesis of peptides containing hydrolytically stable analogs of O-phosphotyrosine

    Terrence R. Burke;Mark S. Smyth;Motoyoshi Nomizu;Akira Otaka

  • Chicoric acid analogues as HIV-1 integrase inhibitors.

    Zhaiwei Lin;Nouri Neamati;He Zhao;Yoshimitsu Kiryu

  • Antiretroviral agents as inhibitors of both human immunodeficiency virus type 1 integrase and protease.

    Abhijit Mazumder;Shaomeng Wang;Nouri Neamati;Marc Nicklaus

  • Structural and functional analyses of minimal phosphopeptides targeting the polo-box domain of polo-like kinase 1

    Sang-Moon Yun;Tinoush Moulaei;Dan Lim;Jeong K. Bang

  • Caffeic acid phenethyl ester induces leukocyte apoptosis, modulates nuclear factor-kappa B and suppresses acute inflammation.

    Zsolt Orban;Nicholas Mitsiades;Terrence R. Burke;Maria Tsokos

  • Structural Determinants for HIV-1 Integrase Inhibition by β-Diketo Acids

    Christophe Marchand;Xuechun Zhang;Godwin C.G. Pais;Kiriana Cowansage

  • Metal-Dependent Inhibition of HIV-1 Integrase by β-Diketo Acids and Resistance of the Soluble Double-Mutant (F185K/C280S)

    Christophe Marchand;Allison A. Johnson;Rajeshri G. Karki;Godwin C. G. Pais

  • Small Molecule Interactions with Protein−Tyrosine Phosphatase PTP1B and Their Use in Inhibitor Design†

    Terrence R. Burke;Bin Ye;Xinjian Yan;Shaomeng Wang

  • Inhibition of SH2 domain/phosphoprotein association by a nonhydrolyzable phosphonopeptide.

    Susan M. Domchek;Kurt R. Auger;Swati Chatterjee;Terrence R. Burke

  • Hydroxylated Aromatic Inhibitors of HIV-1 Integrase.

    T. R. Jun. Burke;M. R. Fesen;A. Mazumder;J. Wang

Frequent Co-Authors

Yves Pommier
Yves Pommier National Institutes of Health
Kenner C. Rice
Kenner C. Rice National Institutes of Health
Christophe Marchand
Christophe Marchand National Institutes of Health
Robert J. Fisher
Robert J. Fisher Science Applications International Corporation (United States)
Peter P. Roller
Peter P. Roller National Institutes of Health
Donald P. Bottaro
Donald P. Bottaro National Institutes of Health
Arthur E. Jacobson
Arthur E. Jacobson National Institutes of Health
Marc C. Nicklaus
Marc C. Nicklaus National Institutes of Health
Akira Otaka
Akira Otaka University of Tokushima
Christoph Rader
Christoph Rader Scripps Research Institute

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