What is he best known for?
The fields of study he is best known for:
Alan Engelman mainly investigates Integrase, Genetics, Molecular biology, DNA and Virus Integration.
His Integrase study integrates concerns from other disciplines, such as Protein structure, Binding domain and Cell biology.
His research brings together the fields of Computational biology and Genetics.
His Molecular biology study combines topics in areas such as Polyadenylation, DNA clamp, Binding site and DNA polymerase II.
His work is dedicated to discovering how DNA, Virology are connected with Gene knockdown and Bovine immunodeficiency virus and other disciplines.
His Virus Integration research includes elements of Barrier-to-autointegration factor, Footprinting, Viral transformation, RNase P and Host factor.
His most cited work include:
- Identification of Host Proteins Required for HIV Infection Through a Functional Genomic Screen (1245 citations)
- Crystal structure of the catalytic domain of HIV-1 integrase: similarity to other polynucleotidyl transferases. (687 citations)
- Retroviral intasome assembly and inhibition of DNA strand transfer (537 citations)
What are the main themes of his work throughout his whole career to date?
The scientist’s investigation covers issues in Integrase, Cell biology, Virology, Molecular biology and DNA.
His Integrase research incorporates themes from Virus Integration, Reverse transcriptase, Mutant and Viral replication.
His Cell biology research is multidisciplinary, incorporating perspectives in Chromatin, Cleavage and polyadenylation specificity factor, Fusion protein and Capsid.
His research investigates the connection with Virology and areas like Integrase inhibitor which intersect with concerns in Allosteric regulation.
His study explores the link between Molecular biology and topics such as Mutation that cross with problems in Peptide sequence.
His DNA study incorporates themes from Retrovirus, Recombinant DNA and Enzyme.
He most often published in these fields:
- Integrase (58.85%)
- Cell biology (31.10%)
- Virology (25.84%)
What were the highlights of his more recent work (between 2017-2021)?
- Cell biology (31.10%)
- Capsid (21.53%)
- Integrase (58.85%)
In recent papers he was focusing on the following fields of study:
Alan Engelman spends much of his time researching Cell biology, Capsid, Integrase, Cleavage and polyadenylation specificity factor and Reverse transcriptase.
The various areas that Alan Engelman examines in his Cell biology study include Ribonucleoprotein, HEK 293 cells and Genome.
His Capsid research is multidisciplinary, incorporating elements of Biophysics, Cypa, Cyclophilin A, Small molecule and Random hexamer.
The study incorporates disciplines such as Virus, Viral replication, Virology, Chromatin and Integrase inhibitor in addition to Integrase.
The concepts of his Virology study are interwoven with issues in DNA and Mutation.
His research integrates issues of Viral envelope, In vitro, Enzyme, Fusion protein and Infectivity in his study of Reverse transcriptase.
Between 2017 and 2021, his most popular works were:
- Molecular Mechanisms for CFIm-Mediated Regulation of mRNA Alternative Polyadenylation (76 citations)
- Capsid-CPSF6 Interaction Licenses Nuclear HIV-1 Trafficking to Sites of Viral DNA Integration. (69 citations)
- Distinct viral reservoirs in individuals with spontaneous control of HIV-1 (41 citations)
In his most recent research, the most cited papers focused on:
Alan Engelman mainly focuses on Cell biology, Capsid, Integrase, Cleavage and polyadenylation specificity factor and Virus.
His Cell biology study combines topics from a wide range of disciplines, such as Chromatin, Messenger RNA and SR protein.
His work carried out in the field of Capsid brings together such families of science as HEK 293 cells, Biophysics, Reverse transcriptase and Cypa.
His research in Integrase tackles topics such as Integrase inhibitor which are related to areas like Allosteric regulation.
His study on Allosteric regulation also encompasses disciplines like
- Virology that connect with fields like DNA,
- Retrovirus that intertwine with fields like Viral replication.
As part of the same scientific family, Alan Engelman usually focuses on Virus, concentrating on Dolutegravir and intersecting with Computational biology, Pharmacophore, Active site and Bictegravir.
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