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Microbiology

D-Index
54
Citations
10418
World Ranking
3963
National Ranking
1537

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Eric M. Poeschla is affiliated with the University of Colorado Anschutz Medical Campus in the United States. Their research spans multiple areas within medicine, immunology, and microbiology, with a significant focus on infectious diseases, epidemiology, virology, immunology, and molecular biology.

The scientist's main research topics include:

  • HIV Research and Treatment
  • Interferon and Immune Responses
  • Cytomegalovirus and Herpesvirus Research
  • SARS-CoV-2 and COVID-19 Research
  • HIV/AIDS Drug Development and Treatment
  • COVID-19 Clinical Research Studies
  • RNA Regulation and Disease

Eric M. Poeschla has contributed to multiple peer-reviewed journals, with frequent publications in venues such as:

  • mBio
  • bioRxiv (Cold Spring Harbor Laboratory)
  • The Journal of Immunology
  • Science
  • Proceedings of the National Academy of Sciences

Their recent notable papers include:

  • "Structural and mechanistic bases for a potent HIV-1 capsid inhibitor," 2020, Science
  • "Interferon resistance of emerging SARS-CoV-2 variants," 2022, Proceedings of the National Academy of Sciences
  • "Decarceration and community re-entry in the COVID-19 era," 2020, The Lancet Infectious Diseases
  • "Sec24C is an HIV-1 host dependency factor crucial for virus replication," 2021, Nature Microbiology
  • "CPSF6-Dependent Targeting of Speckle-Associated Domains Distinguishes Primate from Nonprimate Lentiviral Integration," 2020, mBio

The scientist has collaborated with several frequent co-authors, including James H. Morrison, Alan Engelman, Parmit K. Singh, Caitlin M. Miller, and Hind J. Fadel.

Eric M. Poeschla's scholarly work is situated mainly within the fields of medicine and immunology and microbiology, demonstrating interdisciplinary research approaches to infectious diseases and immune response mechanisms.

They have been recognized as a member of the Association of American Physicians.

Best Publications

  • A role for LEDGF/p75 in targeting HIV DNA integration.

    Angela Ciuffi;Manuel Llano;Eric Poeschla;Christian Hoffmann

  • An essential role for LEDGF/p75 in HIV integration.

    Manuel Llano;Dyana T. Saenz;Anne Meehan;Phonphimon Wongthida

  • Efficient transduction of nondividing human cells by feline immunodeficiency virus lentiviral vectors.

    Eric M. Poeschla;Flossie Wong-Staal;David J. Looney

  • LEDGF/p75 Determines Cellular Trafficking of Diverse Lentiviral but Not Murine Oncoretroviral Integrase Proteins and Is a Component of Functional Lentiviral Preintegration Complexes

    Manuel Llano;Maria Vanegas;Oliver Fregoso;Dyana Saenz

  • A critical role for alternative polyadenylation factor CPSF6 in targeting HIV-1 integration to transcriptionally active chromatin

    Gregory A. Sowd;Erik Serrao;Hao Wang;Weifeng Wang

  • Role of PSIP1/LEDGF/p75 in lentiviral infectivity and integration targeting.

    Heather M. Marshall;Keshet Ronen;Charles Berry;Manuel Llano

  • Progress towards gene therapy for HIV infection.

    Mang Yu;Eric Poeschla;Flossie Wong-Staal

  • Identification and characterization of the chromatin-binding domains of the HIV-1 integrase interactor LEDGF/p75.

    Manuel Llano;Maria Vanegas;Noelle Hutchins;Daniah Thompson

  • Development of HIV vectors for anti-HIV gene therapy

    Eric Poeschla;Pierre Corbeau;Flossie Wong-Staal

  • Lens epithelium-derived growth factor/p75 prevents proteasomal degradation of HIV-1 integrase.

    Manuel Llano;Sharon Delgado;Maria Vanegas;Eric M. Poeschla

  • Identification of the LEDGF/p75 HIV-1 integrase-interaction domain and NLS reveals NLS-independent chromatin tethering

    Maria Vanegas;Manuel Llano;Sharon Delgado;Daniah Thompson

  • Capsid-CPSF6 Interaction Licenses Nuclear HIV-1 Trafficking to Sites of Viral DNA Integration.

    Vasudevan Achuthan;Jill M. Perreira;Gregory A. Sowd;Maritza Puray-Chavez

  • Structural and mechanistic bases for a potent HIV-1 capsid inhibitor

    Stephanie M. Bester;Guochao Wei;Haiyan Zhao;Daniel Adu-Ampratwum

  • A Controlled, Phase 1 Clinical Trial to Evaluate the Safety and Effects in HIV-1 Infected Humans of Autologous Lymphocytes Transduced with a Ribozyme that Cleaves HIV-1 RNA. University of California San Diego, La Jolla, California

    Flossie Wong-Staal;Eric M. Poeschla;David J. Looney;David J. Looney

  • Integrase, LEDGF/p75 and HIV replication.

    Eric M. Poeschla

  • Codon optimization of the HIV-1 vpu and vif genes stabilizes their mRNA and allows for highly efficient Rev-independent expression.

    Kim Lien Nguyen;Manuel Llano;Hirofumi Akari;Eri Miyagi

  • Unintegrated Lentivirus DNA Persistence and Accessibility to Expression in Nondividing Cells: Analysis with Class I Integrase Mutants

    Dyana T. Saenz;Nils Loewen;Mary Peretz;Todd Whitwam

  • Interferon resistance of emerging SARS-CoV-2 variants

    Unknown

  • CXCR4 IS REQUIRED BY A NONPRIMATE LENTIVIRUS : HETEROLOGOUS EXPRESSION OF FELINE IMMUNODEFICIENCY VIRUS IN HUMAN, RODENT, AND FELINE CELLS

    Eric M. Poeschla;David J. Looney;David J. Looney

  • Identification of a Human Immunodeficiency Virus Type 2 (HIV-2) Encapsidation Determinant and Transduction of Nondividing Human Cells by HIV-2-Based Lentivirus Vectors

    Eric Poeschla;James Gilbert;Xinqiang Li;Shiang Huang

  • Comparative requirements for the restriction of retrovirus infection by TRIM5α and TRIMCyp

    Felipe Diaz-Griffero;Alak Kar;Mark Lee;Matthew Stremlau

Frequent Co-Authors

Flossie Wong-Staal
Flossie Wong-Staal University of California, San Diego
Mamuka Kvaratskhelia
Mamuka Kvaratskhelia University of Colorado Denver
Alan Engelman
Alan Engelman Harvard University
Roy Parker
Roy Parker University of Colorado Boulder
Frederic D. Bushman
Frederic D. Bushman University of Pennsylvania
James R. Fuchs
James R. Fuchs The Ohio State University
Stephen Hughes
Stephen Hughes National Cancer Institute
Vineet N. KewalRamani
Vineet N. KewalRamani National Institutes of Health
Thomas E. Morrison
Thomas E. Morrison University of Colorado Anschutz Medical Campus
Paul L. Kaufman
Paul L. Kaufman University of Wisconsin–Madison

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