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Stephen Hughes

D-Index & Metrics

Biology and Biochemistry

D-Index
101
Citations
36167
World Ranking
1446
National Ranking
822

Stephen Hughes publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Stephen Hughes sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 466 publications — 94th percentile

94% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Stephen Hughes D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Stephen Hughes sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 101 D-Index — 93rd percentile

93% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Stephen Hughes is affiliated with the National Cancer Institute in the United States. Their research spans multiple areas within medicine, specifically focusing on infectious diseases, virology, and molecular biology. They have contributed extensively to the fields of HIV research and treatment, including HIV/AIDS drug development and interventions, as well as biochemical and molecular studies related to these topics.

The scientist's recent publications include:

  • Reverse-transcribed SARS-CoV-2 RNA can integrate into the genome of cultured human cells and can be expressed in patient-derived tissues (2021, Proceedings of the National Academy of Sciences)
  • A reference human induced pluripotent stem cell line for large-scale collaborative studies (2022, Cell Stem Cell)
  • HIV-1 viremia not suppressible by antiretroviral therapy can originate from large T cell clones producing infectious virus (2020, Journal of Clinical Investigation)
  • Structural basis for strand-transfer inhibitor binding to HIV intasomes (2020, Science)
  • Integrase Strand Transfer Inhibitors Are Effective Anti-HIV Drugs (2021, Viruses)

Stephen Hughes frequently collaborates with other researchers in the field. Notable coauthors include:

  • Steven J. Smith
  • Xiaolin Wu
  • Terrence R. Burke
  • John W. Mellors
  • Xue Zhi Zhao

Their publications often appear in specific scientific venues, with multiple contributions to journals such as:

  • Viruses
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Proceedings of the National Academy of Sciences
  • PLoS Pathogens
  • mBio

Their main fields of study include Medicine, Immunology and Microbiology, and Biochemistry, Genetics, and Molecular Biology. Within these broader domains, their research touches subfields such as Infectious Diseases, Virology, Molecular Biology, Epidemiology, and Immunology. The scientist's focus on HIV/AIDS encompasses research and treatment, drug development, and interventions, aligning with interests in biochemical and molecular research as well as genetic engineering techniques like CRISPR.

Best Publications

  • A Human Oncogene Formed by the Fusion of Truncated Tropomyosin and Protein Tyrosine Kinase Sequences

    Dionisio Martin-Zanca;Stephen H. Hughes;Mariano Barbacid

  • Specific HIV integration sites are linked to clonal expansion and persistence of infected cells

    F. Maldarelli;X. Wu;L. Su;F. R. Simonetti

  • Reprogramming human T cell function and specificity with non-viral genome targeting

    Theodore L. Roth;Cristina Puig-Saus;Ruby Yu;Ruby Yu;Eric Shifrut;Eric Shifrut

  • The calanolides, a novel HIV-inhibitory class of coumarin derivatives from the tropical rainforest tree, Calophyllum lanigerum.

    Yoel Kashman;Kirk R. Gustafson;Richard W. Fuller;John H. Cardellina

  • Structure and function of HIV-1 reverse transcriptase: molecular mechanisms of polymerization and inhibition.

    Stefan G. Sarafianos;Bruno Marchand;Kalyan Das;Daniel M. Himmel

  • Locations of anti-AIDS drug binding sites and resistance mutations in the three-dimensional structure of HIV-1 reverse transcriptase. Implications for mechanisms of drug inhibition and resistance

    Chris Tantillo;Jianping Ding;Alfredo Jacobo-Molina;Raymond G. Nanni

  • Flexible Use of Nuclear Import Pathways by HIV-1

    KyeongEun Lee;Zandrea Ambrose;Thomas D. Martin;Ilker Oztop

  • Roles of Conformational and Positional Adaptability in Structure-Based Design of TMC125-R165335 (Etravirine) and Related Non-nucleoside Reverse Transcriptase Inhibitors That Are Highly Potent and Effective against Wild-Type and Drug-Resistant HIV-1 Variants

    Kalyan Das;Arthur D. Clark;Paul J. Lewi;Jan Heeres

  • H3K4me3 Interactions with TAF3 Regulate Preinitiation Complex Assembly and Selective Gene Activation

    Shannon M. Lauberth;Takahiro Nakayama;Xiaolin Wu;Andrea L. Ferris

  • Crystal structure of HIV-1 reverse transcriptase in complex with a polypurine tract RNA:DNA.

    Stefan G. Sarafianos;Kalyan Das;Chris Tantillo;Arthur D. Clark

  • In search of a novel anti-HIV drug: multidisciplinary coordination in the discovery of 4-[[4-[[4-[(1E)-2-cyanoethenyl]-2,6-dimethylphenyl]amino]-2- pyrimidinyl]amino]benzonitrile (R278474, rilpivirine).

    Paul A. J. Janssen;Paul J. Lewi;Eddy Arnold;Frits Daeyaert

  • Evaluation of natural products as inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase.

    G T Tan;J M Pezzuto;A D Kinghorn;S H Hughes

  • B-108 Specific HIV integration sites are linked to clonal expansion and persistence of infected cells

    Frank Maldarelli;Xiaolin Wu;Ling Su;Francesco Simonetti

  • High-resolution structures of HIV-1 reverse transcriptase/TMC278 complexes: Strategic flexibility explains potency against resistance mutations.

    Kalyan Das;Joseph D. Bauman;Arthur D. Clark;Yulia V. Frenkel

  • Clonally expanded CD4+ T cells can produce infectious HIV-1 in vivo

    Francesco R. Simonetti;Michele D. Sobolewski;Elizabeth Fyne;Wei Shao

  • Lamivudine (3TC) resistance in HIV-1 reverse transcriptase involves steric hindrance with β-branched amino acids

    Stefan G. Sarafianos;Kalyan Das;Arthur D. Clark;Jianping Ding

  • In vitro anti-HIV activity of biflavonoids isolated from Rhus succedanea and Garcinia multiflora

    Yuh-Meei Lin;Herbert Anderson;Michael T. Flavin;Yeah-Huei S. Pai

  • Structure and functional implications of the polymerase active site region in a complex of HIV-1 RT with a double-stranded DNA template-primer and an antibody Fab fragment at 2.8 A resolution.

    Jianping Ding;Kalyan Das;Yu Hsiou;Stefan G Sarafianos

  • Selective excision of AZTMP by drug-resistant human immunodeficiency virus reverse transcriptase.

    Paul L. Boyer;Stefan G. Sarafianos;Edward Arnold;Stephen H. Hughes

  • Nature, Position, and Frequency of Mutations Made in a Single Cycle of HIV-1 Replication

    Michael E. Abram;Andrea L. Ferris;Wei Shao;W. Gregory Alvord

Frequent Co-Authors

Kalyan Das
Kalyan Das Rega Institute for Medical Research
Stefan G. Sarafianos
Stefan G. Sarafianos University of Missouri
Eddy Arnold
Eddy Arnold Rutgers, The State University of New Jersey
John M. Coffin
John M. Coffin Tufts University
Jianping Ding
Jianping Ding Chinese Academy of Sciences
Mary F. Kearney
Mary F. Kearney National Institutes of Health
John W. Mellors
John W. Mellors University of Pittsburgh
Yves Pommier
Yves Pommier National Institutes of Health
Frank Maldarelli
Frank Maldarelli National Institutes of Health
Reuven Gordon
Reuven Gordon University of Victoria

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Best Scientists Citing Stephen Hughes

Mark A. Wainberg

Mark A. Wainberg

McGill University

Publications: 134

Erik De Clercq

Erik De Clercq

Rega Institute for Medical Research

Publications: 100

Alan Engelman

Alan Engelman

Harvard University

Publications: 78

Eddy Arnold

Eddy Arnold

Rutgers, The State University of New Jersey

Publications: 78

Christophe Pannecouque

Christophe Pannecouque

Rega Institute for Medical Research

Publications: 76

Robert F. Siliciano

Robert F. Siliciano

Johns Hopkins University School of Medicine

Publications: 70

Jan Balzarini

Jan Balzarini

KU Leuven

Publications: 69

Luis Menéndez-Arias

Luis Menéndez-Arias

Spanish National Research Council

Publications: 62

Stefan G. Sarafianos

Stefan G. Sarafianos

University of Missouri

Publications: 58

Kalyan Das

Kalyan Das

Rega Institute for Medical Research

Publications: 55

Jesper Mørk

Jesper Mørk

Technical University of Denmark

Publications: 55

Gilda Tachedjian

Gilda Tachedjian

Burnet Institute

Publications: 45

Robert A. Bambara

Robert A. Bambara

University of Rochester

Publications: 43

Xinyong Liu

Xinyong Liu

Shandong University

Publications: 43

John W. Mellors

John W. Mellors

University of Pittsburgh

Publications: 43

Thomas F. Krauss

Thomas F. Krauss

University of York

Publications: 43

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