D-Index & Metrics Best Publications
Biology and Biochemistry
Canada
2023

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 90 Citations 28,668 483 World Ranking 1563 National Ranking 36

Research.com Recognitions

Awards & Achievements

2023 - Research.com Biology and Biochemistry in Canada Leader Award

Overview

What is he best known for?

The fields of study he is best known for:

  • Quantum mechanics
  • DNA
  • Gene

Stephen H. Hughes mostly deals with Reverse transcriptase, Molecular biology, Virology, Polymerase and DNA. His Reverse transcriptase research integrates issues from Enzyme, Mutant, Binding site and Primer. His research integrates issues of Mutation, Complementary DNA, RNA-Directed DNA Polymerase and Nuclear transport, Cell nucleus in his study of Molecular biology.

The study incorporates disciplines such as Genetics and Drug resistance in addition to Virology. His work carried out in the field of Polymerase brings together such families of science as Protein structure, Discovery and development of nucleoside and nucleotide reverse-transcriptase inhibitors and Active site. His DNA research is multidisciplinary, incorporating elements of RNA and Ternary complex.

His most cited work include:

  • A Human Oncogene Formed by the Fusion of Truncated Tropomyosin and Protein Tyrosine Kinase Sequences (581 citations)
  • The calanolides, a novel HIV-inhibitory class of coumarin derivatives from the tropical rainforest tree, Calophyllum lanigerum. (446 citations)
  • Locations of anti-AIDS drug binding sites and resistance mutations in the three-dimensional structure of HIV-1 reverse transcriptase. Implications for mechanisms of drug inhibition and resistance (444 citations)

What are the main themes of his work throughout his whole career to date?

The scientist’s investigation covers issues in Quantum dot, Reverse transcriptase, Molecular biology, Virology and Photon. His Quantum dot research incorporates themes from Master equation, Condensed matter physics, Quantum optics and Photonic crystal. His work is dedicated to discovering how Reverse transcriptase, Polymerase are connected with Active site and other disciplines.

His Molecular biology study combines topics in areas such as Plasmid, Mutation, Mutant, Murine leukemia virus and Gene. The Virology study combines topics in areas such as Integrase, Vector and Drug resistance. Stephen H. Hughes interconnects Plasmon, Dipole, Molecular physics, Quantum and Cavity quantum electrodynamics in the investigation of issues within Photon.

He most often published in these fields:

  • Quantum dot (20.66%)
  • Reverse transcriptase (19.93%)
  • Molecular biology (19.01%)

What were the highlights of his more recent work (between 2017-2021)?

  • Quantum (10.05%)
  • Virology (18.46%)
  • Quantum dot (20.66%)

In recent papers he was focusing on the following fields of study:

Stephen H. Hughes mainly investigates Quantum, Virology, Quantum dot, Photon and Quantum electrodynamics. His Quantum study combines topics from a wide range of disciplines, such as Plasmon, Quantum optics and Gauge theory. He has researched Virology in several fields, including RNA, Peripheral blood mononuclear cell, Drug resistance and Provirus.

His RNA research focuses on subjects like Virus, which are linked to Gene, Integrase and Reverse transcriptase. His Quantum dot study incorporates themes from Optics, Master equation, Molecular physics, Excitation and Atomic physics. The concepts of his Photon study are interwoven with issues in Nanowire, Computational physics and Dephasing.

Between 2017 and 2021, his most popular works were:

  • Quantization of Quasinormal Modes for Open Cavities and Plasmonic Cavity Quantum Electrodynamics. (73 citations)
  • Capsid-CPSF6 Interaction Licenses Nuclear HIV-1 Trafficking to Sites of Viral DNA Integration. (69 citations)
  • HIV-1 in lymph nodes is maintained by cellular proliferation during antiretroviral therapy (35 citations)

In his most recent research, the most cited papers focused on:

  • Quantum mechanics
  • Gene
  • DNA

His main research concerns Quantum, Virology, Photon, Resonator and Quantum dot. His Quantum research is multidisciplinary, incorporating perspectives in Field and Quantum optics. In the field of Virology, his study on Virus overlaps with subjects such as 2019-20 coronavirus outbreak.

His work focuses on many connections between Photon and other disciplines, such as Quantum electrodynamics, that overlap with his field of interest in Observable, Operator, Electric field and Resonance. His studies in Resonator integrate themes in fields like Quantum mechanics and Dissipative system. His research in Quantum dot intersects with topics in Master equation and Dephasing.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

A Human Oncogene Formed by the Fusion of Truncated Tropomyosin and Protein Tyrosine Kinase Sequences

Dionisio Martin-Zanca;Stephen H. Hughes;Mariano Barbacid.
Nature (1986)

907 Citations

The calanolides, a novel HIV-inhibitory class of coumarin derivatives from the tropical rainforest tree, Calophyllum lanigerum.

Yoel Kashman;Kirk R. Gustafson;Richard W. Fuller;John H. Cardellina.
Journal of Medicinal Chemistry (1992)

771 Citations

Structure and function of HIV-1 reverse transcriptase: molecular mechanisms of polymerization and inhibition.

Stefan G. Sarafianos;Bruno Marchand;Kalyan Das;Daniel M. Himmel.
Journal of Molecular Biology (2009)

627 Citations

Locations of anti-AIDS drug binding sites and resistance mutations in the three-dimensional structure of HIV-1 reverse transcriptase. Implications for mechanisms of drug inhibition and resistance

Chris Tantillo;Jianping Ding;Alfredo Jacobo-Molina;Raymond G. Nanni.
Journal of Molecular Biology (1994)

587 Citations

Extrinsic optical scattering loss in photonic crystal waveguides: role of fabrication disorder and photon group velocity.

S. Hughes;L. Ramunno;Jeff F. Young;J. E. Sipe.
Physical Review Letters (2005)

528 Citations

Crystal structure of HIV-1 reverse transcriptase in complex with a polypurine tract RNA:DNA.

Stefan G. Sarafianos;Kalyan Das;Chris Tantillo;Arthur D. Clark.
The EMBO Journal (2001)

519 Citations

Synthesis and biological activity of novel nonnucleoside inhibitors of HIV-1 reverse transcriptase. 2-Aryl-substituted benzimidazoles.

Thomas Roth;Marshall L. Morningstar;Paul L. Boyer;Stephen H. Hughes.
Journal of Medicinal Chemistry (1997)

490 Citations

Flexible Use of Nuclear Import Pathways by HIV-1

KyeongEun Lee;Zandrea Ambrose;Thomas D. Martin;Ilker Oztop.
Cell Host & Microbe (2010)

466 Citations

In search of a novel anti-HIV drug: multidisciplinary coordination in the discovery of 4-[[4-[[4-[(1E)-2-cyanoethenyl]-2,6-dimethylphenyl]amino]-2- pyrimidinyl]amino]benzonitrile (R278474, rilpivirine).

Paul A. J. Janssen;Paul J. Lewi;Eddy Arnold;Frits Daeyaert.
Journal of Medicinal Chemistry (2005)

452 Citations

B-108 Specific HIV integration sites are linked to clonal expansion and persistence of infected cells

Frank Maldarelli;Xiaolin Wu;Ling Su;Francesco Simonetti.
Journal of Acquired Immune Deficiency Syndromes (2016)

447 Citations

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