His primary areas of investigation include Cell biology, Tight junction, Cell junction, Intestinal mucosa and Epithelium. James L. Madara has included themes like Apical membrane, Transepithelial Migration and Intestinal epithelium in his Cell biology study. His biological study spans a wide range of topics, including Biophysics, Membrane potential, Paracellular transport, Barrier function and Cytoskeleton.
His Cell junction research focuses on Adherens junction and how it relates to Cell membrane permeability and Membrane protein. James L. Madara usually deals with Intestinal mucosa and limits it to topics linked to Proinflammatory cytokine and Flagellin, Effector and Yersinia. His studies deal with areas such as Paracrine signalling, Microbiology and Phosphorylation as well as Epithelium.
James L. Madara spends much of his time researching Cell biology, Epithelium, Tight junction, Immunology and Intestinal epithelium. His Cell biology research incorporates elements of Secretion, Transepithelial Migration and Intestinal mucosa. His Epithelium research is multidisciplinary, incorporating elements of Cotransporter, Chemotaxis and Small intestine.
The various areas that he examines in his Tight junction study include Biophysics, Paracellular transport, Cell junction, Barrier function and Cytoskeleton. His Cell junction study integrates concerns from other disciplines, such as Occludin and Adherens junction. His Intestinal epithelium study incorporates themes from Crypt, Inflammatory bowel disease and Anatomy.
His primary areas of study are Cell biology, Epithelium, Proinflammatory cytokine, Inflammation and Secretion. The study incorporates disciplines such as Intestinal mucosa and Cell junction in addition to Cell biology. James L. Madara does research in Epithelium, focusing on Intestinal epithelium specifically.
The Proinflammatory cytokine study combines topics in areas such as Pathogen, Microbiology, Intracellular, Innate immune system and Flagellin. His Inflammation study combines topics in areas such as Apical membrane and Effector. His Tight junction research integrates issues from Immunologic Surveillance, Biophysics and Permeability.
His main research concerns Cell biology, Proinflammatory cytokine, Intestinal mucosa, Inflammation and Tight junction. His Cell biology research includes themes of Chemotaxis, Paracellular transport and Cell junction. The study incorporates disciplines such as Pathogen, Microbiology, Endocrinology, Flagellin and Effector in addition to Proinflammatory cytokine.
His study focuses on the intersection of Microbiology and fields such as Epithelium with connections in the field of Multiprotein complex, Actin cytoskeleton and Permeability. His Intestinal mucosa study combines topics from a wide range of disciplines, such as Chemokine, Secretion, Interleukin 8 and Immunology. His Immunology research integrates issues from Lamina propria and Intestinal epithelium.
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Cutting Edge: Bacterial Flagellin Activates Basolaterally Expressed TLR5 to Induce Epithelial Proinflammatory Gene Expression
Andrew T. Gewirtz;Tony A. Navas;Sean Lyons;Paul J. Godowski.
Journal of Immunology (2001)
Prokaryotic Regulation of Epithelial Responses by Inhibition of IκB-α Ubiquitination
Andrew S. Neish;Andrew T. Gewirtz;Hui Zeng;Andrew N. Young.
Proinflammatory Cytokines Disrupt Epithelial Barrier Function by Apoptosis-Independent Mechanisms
Matthias Bruewer;Andreas Luegering;Andreas Luegering;Torsten Kucharzik;Torsten Kucharzik;Charles A. Parkos.
Journal of Immunology (2003)
Interferon-gamma directly affects barrier function of cultured intestinal epithelial monolayers.
J L Madara;J Stafford.
Journal of Clinical Investigation (1989)
Molecular physiology and pathophysiology of tight junctions. IV. Regulation of tight junctions by extracellular stimuli: nutrients, cytokines, and immune cells.
A. Nusrat;J. R. Turner;J. L. Madara.
American Journal of Physiology-gastrointestinal and Liver Physiology (2000)
REGULATION OF THE MOVEMENT OF SOLUTES ACROSS TIGHT JUNCTIONS
James L. Madara.
Annual Review of Physiology (1998)
Structural basis for physiological regulation of paracellular pathways in intestinal epithelia.
J. L. Madara;J. L. Madara;J. R. Pappenheimer;J. R. Pappenheimer.
The Journal of Membrane Biology (1987)
Effects of cytochalasin D on occluding junctions of intestinal absorptive cells: further evidence that the cytoskeleton may influence paracellular permeability and junctional charge selectivity.
James L. Madara;David Barenberg;Susan Carlson.
Journal of Cell Biology (1986)
Physiological regulation of epithelial tight junctions is associated with myosin light-chain phosphorylation.
Jerrold R. Turner;Jerrold R. Turner;Brian K. Rill;Susan L. Carlson;Denise Carnes.
American Journal of Physiology-cell Physiology (1997)
Salmonella typhimurium attachment to human intestinal epithelial monolayers: transcellular signalling to subepithelial neutrophils.
Beth A. McCormick;Sean P. Colgan;Charlene Delp-Archer;Samuel I. Miller.
Journal of Cell Biology (1993)
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