James L. Madara

Overview

Best Publications

• Cutting Edge: Bacterial Flagellin Activates Basolaterally Expressed TLR5 to Induce Epithelial Proinflammatory Gene Expression

  Andrew T. Gewirtz;Tony A. Navas;Sean Lyons;Paul J. Godowski

  1710
  Citations

• Prokaryotic Regulation of Epithelial Responses by Inhibition of IκB-α Ubiquitination

  Andrew S. Neish;Andrew T. Gewirtz;Hui Zeng;Andrew N. Young

  1161
  Citations

• Proinflammatory Cytokines Disrupt Epithelial Barrier Function by Apoptosis-Independent Mechanisms

  Matthias Bruewer;Andreas Luegering;Andreas Luegering;Torsten Kucharzik;Torsten Kucharzik;Charles A. Parkos

  1088
  Citations

• Interferon-gamma directly affects barrier function of cultured intestinal epithelial monolayers.

  J L Madara;J Stafford

  918
  Citations

• REGULATION OF THE MOVEMENT OF SOLUTES ACROSS TIGHT JUNCTIONS

  James L. Madara

  653
  Citations

• Molecular physiology and pathophysiology of tight junctions. IV. Regulation of tight junctions by extracellular stimuli: nutrients, cytokines, and immune cells.

  A. Nusrat;J. R. Turner;J. L. Madara

  649
  Citations

• Structural basis for physiological regulation of paracellular pathways in intestinal epithelia.

  J. L. Madara;J. L. Madara;J. R. Pappenheimer;J. R. Pappenheimer

  648
  Citations

• Physiological regulation of epithelial tight junctions is associated with myosin light-chain phosphorylation.

  Jerrold R. Turner;Jerrold R. Turner;Brian K. Rill;Susan L. Carlson;Denise Carnes

  621
  Citations

• Effects of cytochalasin D on occluding junctions of intestinal absorptive cells: further evidence that the cytoskeleton may influence paracellular permeability and junctional charge selectivity.

  James L. Madara;David Barenberg;Susan Carlson

  616
  Citations

• Salmonella typhimurium attachment to human intestinal epithelial monolayers: transcellular signalling to subepithelial neutrophils.

  Beth A. McCormick;Sean P. Colgan;Charlene Delp-Archer;Samuel I. Miller

  566
  Citations

• Tight junctions are membrane microdomains

  A. Nusrat;C.A. Parkos;P. Verkade;C.S. Foley

  553
  Citations

• Intraepithelial eosinophils: a new diagnostic criterion for reflux esophagitis.

  Harland S. Winter;James L. Madara;Richard J. Stafford;Richard J. Grand

  532
  Citations

• Salmonella typhimurium translocates flagellin across intestinal epithelia, inducing a proinflammatory response

  Andrew T. Gewirtz;Peter O. Simon;Clare K. Schmitt;Laura J. Taylor

  516
  Citations

• Occluding junction structure-function relationships in a cultured epithelial monolayer.

  J L Madara;K Dharmsathaphorn

  509
  Citations

• Rho protein regulates tight junctions and perijunctional actin organization in polarized epithelia.

  A Nusrat;M Giry;J R Turner;S P Colgan

  505
  Citations

• Clostridium difficile toxin A perturbs cytoskeletal structure and tight junction permeability of cultured human intestinal epithelial monolayers.

  G Hecht;C Pothoulakis;J T LaMont;J L Madara

  459
  Citations

• Design of lipoxin A4 stable analogs that block transmigration and adhesion of human neutrophils.

  Charles N. Serhan;Jane F. Maddox;Nicos A. Petasis;Irini Akritopoulou-Zanze

  455
  Citations

• Integrin alpha E beta 7 mediates adhesion of T lymphocytes to epithelial cells.

  K L Cepek;C M Parker;J L Madara;M B Brenner

  445
  Citations

• Loosening tight junctions. Lessons from the intestine.

  J L Madara

  438
  Citations

• 5'-adenosine monophosphate is the neutrophil-derived paracrine factor that elicits chloride secretion from T84 intestinal epithelial cell monolayers.

  James L. Madara;Thomas W. Patapoff;Beth Gillece-Castro;Sean P. Colgan

  426
  Citations