D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 75 Citations 23,014 195 World Ranking 2232 National Ranking 166

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Internal medicine

Michael Fromm focuses on Tight junction, Claudin, Molecular biology, Cell biology and Occludin. His biological study spans a wide range of topics, including Epithelium, Pathology, Transfection, Paracellular transport and Barrier function. His studies deal with areas such as Exocytosis, Biophysics, Transcellular and Transmembrane protein as well as Paracellular transport.

The various areas that Michael Fromm examines in his Claudin study include Endoplasmic reticulum and Cytokine. Michael Fromm has researched Molecular biology in several fields, including Tumor necrosis factor alpha, Caco-2, Gene expression and Ion transporter. The concepts of his Cell biology study are interwoven with issues in Cell culture, Protein family, Membrane protein, Rac GTP-Binding Proteins and Cell polarity.

His most cited work include:

  • Complex Phenotype of Mice Lacking Occludin, a Component of Tight Junction Strands (886 citations)
  • Interleukin-13 Is the Key Effector Th2 Cytokine in Ulcerative Colitis That Affects Epithelial Tight Junctions, Apoptosis, and Cell Restitution (836 citations)
  • Changes in expression and distribution of claudin 2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohn’s disease (796 citations)

What are the main themes of his work throughout his whole career to date?

His primary scientific interests are in Tight junction, Paracellular transport, Internal medicine, Claudin and Cell biology. His work carried out in the field of Tight junction brings together such families of science as Barrier function, Epithelium and Molecular biology. His research in Barrier function tackles topics such as Pathology which are related to areas like Inflammation.

His studies in Paracellular transport integrate themes in fields like Conductance, Biophysics, Transcellular and Ion channel. The study incorporates disciplines such as Gastroenterology, Endocrinology and Ion transporter in addition to Internal medicine. Michael Fromm combines subjects such as Downregulation and upregulation and Cell junction with his study of Cell biology.

He most often published in these fields:

  • Tight junction (43.08%)
  • Paracellular transport (26.46%)
  • Internal medicine (25.85%)

What were the highlights of his more recent work (between 2013-2021)?

  • Tight junction (43.08%)
  • Paracellular transport (26.46%)
  • Claudin (24.31%)

In recent papers he was focusing on the following fields of study:

His main research concerns Tight junction, Paracellular transport, Claudin, Cell biology and Biophysics. Michael Fromm interconnects Inflammation, Immunology and Barrier function in the investigation of issues within Tight junction. His Paracellular transport research is multidisciplinary, incorporating perspectives in Epithelium, Transcellular and Microbiology.

His Claudin study combines topics from a wide range of disciplines, such as Molecular biology, Occludin, Tubule and Cell polarity. His Cell biology research is multidisciplinary, incorporating perspectives in Lipopolysaccharide, Downregulation and upregulation and Small intestine. The Biophysics study combines topics in areas such as Amino acid, Membrane, Permeability and Ion channel.

Between 2013 and 2021, his most popular works were:

  • Tight junction, selective permeability, and related diseases. (156 citations)
  • Proinflammatory cytokine-induced tight junction remodeling through dynamic self-assembly of claudins. (68 citations)
  • Celiac Disease: Role of the Epithelial Barrier (65 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Internal medicine

Michael Fromm spends much of his time researching Tight junction, Claudin, Paracellular transport, Biophysics and Cell biology. He combines subjects such as Cell junction, Immunology, Microbiology, Stem cell and Proinflammatory cytokine with his study of Tight junction. His work on Inflammation as part of general Immunology study is frequently linked to Villous atrophy, therefore connecting diverse disciplines of science.

Michael Fromm performs integrative Claudin and Context research in his work. His Biophysics research is multidisciplinary, incorporating elements of Amino acid, Biochemistry and Ion channel. His Cell biology research includes themes of Internal medicine, Cytokine, Downregulation and upregulation and Endocrinology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Complex Phenotype of Mice Lacking Occludin, a Component of Tight Junction Strands

Mitinori Saitou;Mikio Furuse;Hiroyuki Sasaki;Jörg-Dieter Schulzke.
Molecular Biology of the Cell (2000)

1145 Citations

Interleukin-13 Is the Key Effector Th2 Cytokine in Ulcerative Colitis That Affects Epithelial Tight Junctions, Apoptosis, and Cell Restitution

Frank Heller;Peter Florian;Christian Bojarski;Jan Richter.
Gastroenterology (2005)

1071 Citations

Changes in expression and distribution of claudin 2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohn’s disease

Sebastian Zeissig;Nataly Bürgel;Dorothee Günzel;Jan Richter.
Gut (2007)

1022 Citations

Claudin-2 expression induces cation-selective channels in tight junctions of epithelial cells.

Salah Amasheh;Noga Meiri;Alfred H. Gitter;Torsten Schöneberg.
Journal of Cell Science (2002)

812 Citations

Altered tight junction structure contributes to the impaired epithelial barrier function in ulcerative colitis

Heinz Schmitz;Christian Barmeyer;MichaeL Fromm;Norbert Runkel.
Gastroenterology (1999)

560 Citations

Transfer of foreign genes into intact maize cells with high-velocity microprojectiles

Theodore M. Klein;Michael Fromm;Arthur Weissinger;Dwight Tomes.
Proceedings of the National Academy of Sciences of the United States of America (1988)

459 Citations

E‐cadherin is essential for in vivo epidermal barrier function by regulating tight junctions

Judith A Tunggal;Iris Helfrich;Annika Schmitz;Heinz Schwarz.
The EMBO Journal (2005)

435 Citations

Tumor necrosis factor-alpha (TNFalpha) regulates the epithelial barrier in the human intestinal cell line HT-29/B6.

Heinz Schmitz;Michael Fromm;Carl J. Bentzel;Peter Scholz.
Journal of Cell Science (1999)

432 Citations

Crypts are the site of intestinal fluid and electrolyte secretion

Michael J. Welsh;Philip L. Smith;Michael Fromm;Raymond A. Frizzell.
Science (1982)

404 Citations

Stable genetic transformation of intact Nicotiana cells by the particle bombardment process

Theodore M. Klein;Elisabeth C. Harper;Zora Svab;John C. Sanford.
Proceedings of the National Academy of Sciences of the United States of America (1988)

363 Citations

If you think any of the details on this page are incorrect, let us know.

Contact us

Best Scientists Citing Michael Fromm

Jerrold R. Turner

Jerrold R. Turner

Brigham and Women's Hospital

Publications: 99

Asma Nusrat

Asma Nusrat

University of Michigan–Ann Arbor

Publications: 52

Mikio Furuse

Mikio Furuse

The Graduate University for Advanced Studies, SOKENDAI

Publications: 43

Takashi Kojima

Takashi Kojima

Sapporo Medical University

Publications: 42

Dorothee Günzel

Dorothee Günzel

Charité - University Medicine Berlin

Publications: 41

Norimasa Sawada

Norimasa Sawada

Sapporo Medical University

Publications: 40

Sachiko Tsukita

Sachiko Tsukita

Osaka University

Publications: 33

Ingolf E. Blasig

Ingolf E. Blasig

Leibniz Institute for Neurobiology

Publications: 32

Charles A. Parkos

Charles A. Parkos

Emory University

Publications: 31

James M. Anderson

James M. Anderson

National Institutes of Health

Publications: 31

Markus F. Neurath

Markus F. Neurath

University of Erlangen-Nuremberg

Publications: 29

Alessio Fasano

Alessio Fasano

Massachusetts General Hospital

Publications: 29

Andre G. Buret

Andre G. Buret

University of Calgary

Publications: 29

Kim E. Barrett

Kim E. Barrett

University of California, San Diego

Publications: 27

Jörg-Dieter Schulzke

Jörg-Dieter Schulzke

Charité - University Medicine Berlin

Publications: 27

Hartwig Wolburg

Hartwig Wolburg

University of Tübingen

Publications: 26

Trending Scientists

Otmar Scherzer

Otmar Scherzer

University of Vienna

Brian Norton

Brian Norton

Tyndall National Institute

Guowei Yang

Guowei Yang

Sun Yat-sen University

Dongzhi Zhang

Dongzhi Zhang

China University of Petroleum, Beijing

James F. Cahill

James F. Cahill

University of Alberta

Robert Rottapel

Robert Rottapel

University of Toronto

Mary E. Lidstrom

Mary E. Lidstrom

University of Washington

Michael J. Waters

Michael J. Waters

University of Queensland

Henry Metzger

Henry Metzger

National Institutes of Health

Xuzhi Zhou

Xuzhi Zhou

Peking University

Casimir A. Fornal

Casimir A. Fornal

Princeton University

Romain Valabregue

Romain Valabregue

Université Paris Cité

Phyllis B. Silver

Phyllis B. Silver

National Institutes of Health

Mark A. Blais

Mark A. Blais

Harvard University

Tim Valentine

Tim Valentine

Goldsmiths University of London

Timothy D. Noakes

Timothy D. Noakes

University of Cape Town

Something went wrong. Please try again later.