World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
96
Citations
31238
World Ranking
1837
National Ranking
123

Overview

Michael Fromm is affiliated with Charité - University Medicine Berlin in Germany. Their research spans multiple fields including Neuroscience, Biochemistry, Genetics and Molecular Biology, and Medicine. Within these broad domains, their subfields of expertise include Neurology, Molecular Biology, Astronomy and Astrophysics, Cancer Research, and Nuclear and High Energy Physics.

The scientist's work addresses several key topics such as Barrier Structure and Function Studies, Neurological Disease Mechanisms and Treatments, Gut microbiota and health, Astrophysical Phenomena and Observations, Connexins and lens biology, Inflammatory Bowel Disease, and Cancer-related molecular mechanisms research.

Frequent publication venues where Michael Fromm's work appears include:

  • Astronomy and Astrophysics
  • International Journal of Molecular Sciences
  • The FASEB Journal
  • International Journal of Radiation Oncology*Biology*Physics
  • Biochimica et Biophysica Acta (BBA) - Biomembranes

Their recent papers illustrate a focus on the molecular and cellular mechanisms underlying tight junctions and related physiological processes:

  • "Molecular architecture and assembly of the tight junction backbone," 2020, Biochimica et Biophysica Acta (BBA) - Biomembranes
  • "A short guide to the tight junction," 2024, Journal of Cell Science
  • "MSH1-induced heritable enhanced growth vigor through grafting is associated with the RdDM pathway in plants," 2020, Nature Communications
  • "Expression of tricellular tight junction proteins and the paracellular macromolecule barrier are recovered in remission of ulcerative colitis," 2021, BMC Gastroenterology
  • "Special Issue on "The Tight Junction and Its Proteins: More than Just a Barrier"," 2020, International Journal of Molecular Sciences

Michael Fromm has collaborated frequently with several coauthors, highlighting the interdisciplinary nature of their research. These frequent collaborators include Susanne M. Krug, Alejandro Cruz-Osorio, Xiaopeng Cheng, Yuzhu Cui, and Roger Deane.

Best Publications

  • Complex Phenotype of Mice Lacking Occludin, a Component of Tight Junction Strands

    Mitinori Saitou;Mikio Furuse;Hiroyuki Sasaki;Jörg-Dieter Schulzke

  • Changes in expression and distribution of claudin 2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohn’s disease

    Sebastian Zeissig;Nataly Bürgel;Dorothee Günzel;Jan Richter

  • Interleukin-13 Is the Key Effector Th2 Cytokine in Ulcerative Colitis That Affects Epithelial Tight Junctions, Apoptosis, and Cell Restitution

    Frank Heller;Peter Florian;Christian Bojarski;Jan Richter

  • Claudin-2 expression induces cation-selective channels in tight junctions of epithelial cells.

    Salah Amasheh;Noga Meiri;Alfred H. Gitter;Torsten Schöneberg

  • Altered tight junction structure contributes to the impaired epithelial barrier function in ulcerative colitis

    Heinz Schmitz;Christian Barmeyer;MichaeL Fromm;Norbert Runkel

  • E‐cadherin is essential for in vivo epidermal barrier function by regulating tight junctions

    Judith A Tunggal;Iris Helfrich;Annika Schmitz;Heinz Schwarz

  • Transfer of foreign genes into intact maize cells with high-velocity microprojectiles

    Theodore M. Klein;Michael Fromm;Arthur Weissinger;Dwight Tomes

  • Tumor necrosis factor-alpha (TNFalpha) regulates the epithelial barrier in the human intestinal cell line HT-29/B6.

    Heinz Schmitz;Michael Fromm;Carl J. Bentzel;Peter Scholz

  • Claudin-2, a component of the tight junction, forms a paracellular water channel.

    Rita Rosenthal;Susanne Milatz;Susanne M. Krug;Beibei Oelrich

  • Epithelial Tight Junctions in Intestinal Inflammation

    Joerg D. Schulzke;Svenja Ploeger;Maren Amasheh;Anja Fromm

  • Crypts are the site of intestinal fluid and electrolyte secretion

    Michael J. Welsh;Philip L. Smith;Michael Fromm;Raymond A. Frizzell

  • Claudins and other tight junction proteins.

    Dorothee Günzel;Michael Fromm

  • Epithelial transport and barrier function in occludin-deficient mice

    J.D. Schulzke;A.H. Gitter;A.H. Gitter;J. Mankertz;S. Spiegel

  • Tricellulin Forms a Barrier to Macromolecules in Tricellular Tight Junctions without Affecting Ion Permeability

    Susanne M. Krug;Salah Amasheh;Jan F. Richter;Susanne Milatz

  • Expression from the human occludin promoter is affected by tumor necrosis factor alpha and interferon gamma

    J. Mankertz;S. Tavalali;H. Schmitz;A. Mankertz

  • Stable genetic transformation of intact Nicotiana cells by the particle bombardment process

    Theodore M. Klein;Elisabeth C. Harper;Zora Svab;John C. Sanford

  • Downregulation of epithelial apoptosis and barrier repair in active Crohn’s disease by tumour necrosis factor α antibody treatment

    S Zeissig;C Bojarski;N Buergel;J Mankertz

  • Tight junction, selective permeability, and related diseases.

    Susanne M. Krug;Jörg D. Schulzke;Michael Fromm

  • Effect of chronic Giardia lamblia infection on epithelial transport and barrier function in human duodenum.

    Hanno Troeger;Hans-Joerg Epple;Thomas Schneider;Ulrich Wahnschaffe

  • Determinants of colonic barrier function in inflammatory bowel disease and potential therapeutics.

    Nina A. Hering;Michael Fromm;Jörg-Dieter Schulzke

Frequent Co-Authors

Jörg-Dieter Schulzke
Jörg-Dieter Schulzke Charité - University Medicine Berlin
Dorothee Günzel
Dorothee Günzel Charité - University Medicine Berlin
Martin Zeitz
Martin Zeitz Charité - University Medicine Berlin
Britta Siegmund
Britta Siegmund Humboldt-Universität zu Berlin
Otmar Huber
Otmar Huber Friedrich Schiller University Jena
Trinad Chakraborty
Trinad Chakraborty University of Giessen
Christoph Loddenkemper
Christoph Loddenkemper Charité - University Medicine Berlin
Torsten Schöneberg
Torsten Schöneberg Leipzig University
Ingolf E. Blasig
Ingolf E. Blasig Leibniz Institute for Neurobiology
Thomas Schneider
Thomas Schneider Technical University of Darmstadt

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