Michael Fromm focuses on Tight junction, Claudin, Molecular biology, Cell biology and Occludin. His biological study spans a wide range of topics, including Epithelium, Pathology, Transfection, Paracellular transport and Barrier function. His studies deal with areas such as Exocytosis, Biophysics, Transcellular and Transmembrane protein as well as Paracellular transport.
The various areas that Michael Fromm examines in his Claudin study include Endoplasmic reticulum and Cytokine. Michael Fromm has researched Molecular biology in several fields, including Tumor necrosis factor alpha, Caco-2, Gene expression and Ion transporter. The concepts of his Cell biology study are interwoven with issues in Cell culture, Protein family, Membrane protein, Rac GTP-Binding Proteins and Cell polarity.
His primary scientific interests are in Tight junction, Paracellular transport, Internal medicine, Claudin and Cell biology. His work carried out in the field of Tight junction brings together such families of science as Barrier function, Epithelium and Molecular biology. His research in Barrier function tackles topics such as Pathology which are related to areas like Inflammation.
His studies in Paracellular transport integrate themes in fields like Conductance, Biophysics, Transcellular and Ion channel. The study incorporates disciplines such as Gastroenterology, Endocrinology and Ion transporter in addition to Internal medicine. Michael Fromm combines subjects such as Downregulation and upregulation and Cell junction with his study of Cell biology.
His main research concerns Tight junction, Paracellular transport, Claudin, Cell biology and Biophysics. Michael Fromm interconnects Inflammation, Immunology and Barrier function in the investigation of issues within Tight junction. His Paracellular transport research is multidisciplinary, incorporating perspectives in Epithelium, Transcellular and Microbiology.
His Claudin study combines topics from a wide range of disciplines, such as Molecular biology, Occludin, Tubule and Cell polarity. His Cell biology research is multidisciplinary, incorporating perspectives in Lipopolysaccharide, Downregulation and upregulation and Small intestine. The Biophysics study combines topics in areas such as Amino acid, Membrane, Permeability and Ion channel.
Michael Fromm spends much of his time researching Tight junction, Claudin, Paracellular transport, Biophysics and Cell biology. He combines subjects such as Cell junction, Immunology, Microbiology, Stem cell and Proinflammatory cytokine with his study of Tight junction. His work on Inflammation as part of general Immunology study is frequently linked to Villous atrophy, therefore connecting diverse disciplines of science.
Michael Fromm performs integrative Claudin and Context research in his work. His Biophysics research is multidisciplinary, incorporating elements of Amino acid, Biochemistry and Ion channel. His Cell biology research includes themes of Internal medicine, Cytokine, Downregulation and upregulation and Endocrinology.
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Complex Phenotype of Mice Lacking Occludin, a Component of Tight Junction Strands
Mitinori Saitou;Mikio Furuse;Hiroyuki Sasaki;Jörg-Dieter Schulzke.
Molecular Biology of the Cell (2000)
Interleukin-13 Is the Key Effector Th2 Cytokine in Ulcerative Colitis That Affects Epithelial Tight Junctions, Apoptosis, and Cell Restitution
Frank Heller;Peter Florian;Christian Bojarski;Jan Richter.
Gastroenterology (2005)
Changes in expression and distribution of claudin 2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohn’s disease
Sebastian Zeissig;Nataly Bürgel;Dorothee Günzel;Jan Richter.
Gut (2007)
Claudin-2 expression induces cation-selective channels in tight junctions of epithelial cells.
Salah Amasheh;Noga Meiri;Alfred H. Gitter;Torsten Schöneberg.
Journal of Cell Science (2002)
Altered tight junction structure contributes to the impaired epithelial barrier function in ulcerative colitis
Heinz Schmitz;Christian Barmeyer;MichaeL Fromm;Norbert Runkel.
Gastroenterology (1999)
Transfer of foreign genes into intact maize cells with high-velocity microprojectiles
Theodore M. Klein;Michael Fromm;Arthur Weissinger;Dwight Tomes.
Proceedings of the National Academy of Sciences of the United States of America (1988)
E‐cadherin is essential for in vivo epidermal barrier function by regulating tight junctions
Judith A Tunggal;Iris Helfrich;Annika Schmitz;Heinz Schwarz.
The EMBO Journal (2005)
Tumor necrosis factor-alpha (TNFalpha) regulates the epithelial barrier in the human intestinal cell line HT-29/B6.
Heinz Schmitz;Michael Fromm;Carl J. Bentzel;Peter Scholz.
Journal of Cell Science (1999)
Crypts are the site of intestinal fluid and electrolyte secretion
Michael J. Welsh;Philip L. Smith;Michael Fromm;Raymond A. Frizzell.
Science (1982)
Stable genetic transformation of intact Nicotiana cells by the particle bombardment process
Theodore M. Klein;Elisabeth C. Harper;Zora Svab;John C. Sanford.
Proceedings of the National Academy of Sciences of the United States of America (1988)
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