D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 65 Citations 18,946 124 World Ranking 4135 National Ranking 274

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • Cell membrane
  • Genetics

The scientist’s investigation covers issues in Cell biology, Radixin, Moesin, Ezrin and Tight junction. The Cell biology study combines topics in areas such as Adherens junction, Molecular biology, Membrane protein and Cytoskeleton. Her Radixin research incorporates themes from Bilirubin, Internal medicine and Multidrug resistance-associated protein 2.

Sachiko Tsukita has included themes like Blood vessel, Artery, Aorta, Anatomy and Circulatory system in her Moesin study. Her work in Ezrin tackles topics such as Phosphorylation which are related to areas like Kinase and Microfilament. Her study on Claudin is often connected to RNA interference as part of broader study in Tight junction.

Her most cited work include:

  • Rho-Kinase Phosphorylates COOH-terminal Threonines of Ezrin/Radixin/Moesin (ERM) Proteins and Regulates Their Head-to-Tail Association (763 citations)
  • Tricellulin constitutes a novel barrier at tricellular contacts of epithelial cells (575 citations)
  • Tricellulin constitutes a novel barrier at tricellular contacts of epithelial cells (575 citations)

What are the main themes of her work throughout her whole career to date?

Sachiko Tsukita mostly deals with Cell biology, Tight junction, Claudin, Radixin and Moesin. Her study in Cell biology is interdisciplinary in nature, drawing from both Membrane protein, Adherens junction and Cytoskeleton. Her research investigates the connection with Tight junction and areas like Cell junction which intersect with concerns in Cell polarity.

Her Claudin research incorporates elements of Endocrinology, Extracellular, Immunology, Internal medicine and Cell adhesion. The study incorporates disciplines such as FERM domain, Secretion and Actin cytoskeleton in addition to Radixin. Her Moesin study necessitates a more in-depth grasp of Ezrin.

She most often published in these fields:

  • Cell biology (80.89%)
  • Tight junction (40.76%)
  • Claudin (31.21%)

What were the highlights of her more recent work (between 2017-2021)?

  • Cell biology (80.89%)
  • Tight junction (40.76%)
  • Microtubule (13.38%)

In recent papers she was focusing on the following fields of study:

Sachiko Tsukita spends much of her time researching Cell biology, Tight junction, Microtubule, Claudin and Adherens junction. Her Cell biology research includes elements of Downregulation and upregulation, Cell growth and Cytoskeleton. Her work in Tight junction addresses subjects such as Barrier function, which are connected to disciplines such as Epithelium.

Her work deals with themes such as Cilium, Basal body, Cingulin and Actin, which intersect with Microtubule. Her studies deal with areas such as Endocrinology, Cell adhesion and Internal medicine as well as Claudin. Her biological study deals with issues like Myosin, which deal with fields such as Apical constriction and Phosphatase.

Between 2017 and 2021, her most popular works were:

  • The Claudins: From Tight Junctions to Biological Systems. (83 citations)
  • Morphologic determinant of tight junctions revealed by claudin-3 structures. (28 citations)
  • Interleukin 22 Expands Transit-Amplifying Cells While Depleting Lgr5+ Stem Cells via Inhibition of Wnt and Notch Signaling. (26 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • Cell membrane
  • Genetics

Her primary scientific interests are in Tight junction, Claudin, Cell biology, Cell adhesion and CLDN3. Her biological study spans a wide range of topics, including Microtubule, Cytoskeleton, Actin and Apical junction complex, Adherens junction. Her Claudin study combines topics from a wide range of disciplines, such as Biophysics, Cell adhesion molecule and In vivo.

In the subject of general Cell biology, her work in Barrier function is often linked to Inflammatory bowel disease, thereby combining diverse domains of study. Her research integrates issues of Epithelium, Helix, Mutant, Transmembrane domain and Protein structure in her study of Cell adhesion. Her CLDN3 study also includes fields such as

  • Internal medicine which intersects with area such as Atopic dermatitis,
  • SWEAT most often made with reference to Endocrinology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Rho-Kinase Phosphorylates COOH-terminal Threonines of Ezrin/Radixin/Moesin (ERM) Proteins and Regulates Their Head-to-Tail Association

Takeshi Matsui;Masato Maeda;Yoshinori Doi;Shigenobu Yonemura.
Journal of Cell Biology (1998)

1131 Citations

Tricellulin constitutes a novel barrier at tricellular contacts of epithelial cells

Junichi Ikenouchi;Mikio Furuse;Kyoko Furuse;Hiroyuki Sasaki.
Journal of Cell Biology (2005)

788 Citations

ZO-1 and ZO-2 Independently Determine Where Claudins Are Polymerized in Tight-Junction Strand Formation

Kazuaki Umeda;Junichi Ikenouchi;Sayaka Katahira-Tayama;Kyoko Furuse.
Cell (2006)

753 Citations

Ezrin/Radixin/Moesin (ERM) Proteins Bind to a Positively Charged Amino Acid Cluster in the Juxta-Membrane Cytoplasmic Domain of CD44, CD43, and ICAM-2

Shigenobu Yonemura;Motohiro Hirao;Yoshinori Doi;Nobuyuki Takahashi.
Journal of Cell Biology (1998)

673 Citations

Cortical actin organization: lessons from ERM (ezrin/radixin/moesin) proteins.

Sachiko Tsukita;Shigenobu Yonemura.
Journal of Biological Chemistry (1999)

622 Citations

The FERM domain: A unique module involved in the linkage of cytoplasmic proteins to the membrane

Athar H. Chishti;Anthony C. Kim;Shirin M. Marfatia;Mohini Lutchman.
Trends in Biochemical Sciences (1998)

618 Citations

Direct Interaction of the Rho GDP Dissociation Inhibitor with Ezrin/Radixin/Moesin Initiates the Activation of the Rho Small G Protein

Kazuo Takahashi;Takuya Sasaki;Akiko Mammoto;Kenji Takaishi.
Journal of Biological Chemistry (1997)

613 Citations

Molecular linkage between cadherins and actin filaments in cell-cell adherens junctions.

Shoichiro Tsukita;Sachiko Tsukita;Akira Nagafuchi;Shigenobu Yonemura.
Current Opinion in Cell Biology (1992)

485 Citations

Induction of polarized cell-cell association and retardation of growth by activation of the E-cadherin-catenin adhesion system in a dispersed carcinoma line.

Mitsuko Watabe;Akira Nagafuchi;Sachiko Tsukita;Masatoshi Takeichi.
Journal of Cell Biology (1994)

475 Citations

Predicted expansion of the claudin multigene family.

Katsuhiko Mineta;Yasuko Yamamoto;Yasuko Yamamoto;Yuji Yamazaki;Hiroo Tanaka.
FEBS Letters (2011)

457 Citations

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