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Shoichiro Tsukita

Shoichiro Tsukita

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Biology and Biochemistry
Japan
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
130
Citations
73721
World Ranking
401
National Ranking
15

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Japan Leader Award

Overview

Shoichiro Tsukita was affiliated with Kyoto University in Japan. Their research spanned multiple disciplines within medicine and engineering, focusing primarily on surgical simulation, anatomy, and oncology. The work contributed to areas including surgical simulation and training, anatomy and medical technology, and colorectal cancer surgical treatments.

The scientist's recent publications included a paper titled "Development of anatomically accurate digital organ models for surgical simulation and training," published in 2025 in the journal PLoS ONE. This article involved advancements in digital modeling for surgical education and simulation.

Frequent coauthors collaborating with Shoichiro Tsukita included:

  • Takashi Kimura
  • Kazuaki Takiguchi
  • Makoto Muto
  • Hiroto Chiba
  • Naoya Sato

Their research output appeared predominantly in the journal PLoS ONE. Shoichiro Tsukita authored work in key publication venues connected to biomedical and clinical research.

The main fields of study were medicine and engineering, with more specific subfields addressing surgery, biomedical engineering, and oncology. These reflected their interdisciplinary approach that integrated clinical knowledge with engineering techniques to enhance surgical procedures and treatments.

Main topics covered in the scientific work included:

  • Surgical Simulation and Training
  • Anatomy and Medical Technology
  • Colorectal Cancer Surgical Treatments

Shoichiro Tsukita's profile indicates a focus on developing technical methodologies and digital solutions to support surgical practices, particularly in the context of colorectal cancer treatment.

Best Publications

  • Multifunctional strands in tight junctions.

    Shoichiro Tsukita;Mikio Furuse;Masahiko Itoh

  • Claudin-1 and -2: Novel Integral Membrane Proteins Localizing at Tight Junctions with No Sequence Similarity to Occludin

    Mikio Furuse;Kohji Fujita;Takashi Hiiragi;Kazushi Fujimoto

  • Size-selective loosening of the blood-brain barrier in claudin-5–deficient mice

    Takehiro Nitta;Masaki Hata;Shimpei Gotoh;Yoshiteru Seo

  • Claudin-based tight junctions are crucial for the mammalian epidermal barrier a lesson from claudin-1–deficient mice

    Mikio Furuse;Masaki Hata;Kyoko Furuse;Yoko Yoshida

  • Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands

    Kazumasa Morita;Mikio Furuse;Kazushi Fujimoto;Shoichiro Tsukita

  • Direct Binding of Three Tight Junction-Associated Maguks, Zo-1, Zo-2, and Zo-3, with the Cooh Termini of Claudins

    Masahiko Itoh;Mikio Furuse;Kazumasa Morita;Koji Kubota

  • Complex Phenotype of Mice Lacking Occludin, a Component of Tight Junction Strands

    Mitinori Saitou;Mikio Furuse;Hiroyuki Sasaki;Jörg-Dieter Schulzke

  • A single gene product, claudin-1 or -2, reconstitutes tight junction strands and recruits occludin in fibroblasts.

    Mikio Furuse;Hiroyuki Sasaki;Kazushi Fujimoto;Shoichiro Tsukita

  • Endothelial Claudin: Claudin-5/Tmvcf Constitutes Tight Junction Strands in Endothelial Cells

    Kazumasa Morita;Hiroyuki Sasaki;Mikio Furuse;Shoichiro Tsukita

  • Direct association of occludin with ZO-1 and its possible involvement in the localization of occludin at tight junctions.

    M Furuse;M Itoh;T Hirase;A Nagafuchi

  • ERM family members as molecular linkers between the cell surface glycoprotein CD44 and actin-based cytoskeletons.

    S Tsukita;K Oishi;N Sato;J Sagara

  • Manner of Interaction of Heterogeneous Claudin Species within and between Tight Junction Strands

    Mikio Furuse;Hiroyuki Sasaki;Shoichiro Tsukita

  • Conversion of zonulae occludentes from tight to leaky strand type by introducing claudin-2 into Madin-Darby canine kidney I cells.

    Mikio Furuse;Kyoko Furuse;Hiroyuki Sasaki;Shoichiro Tsukita

  • Rho-Kinase Phosphorylates COOH-terminal Threonines of Ezrin/Radixin/Moesin (ERM) Proteins and Regulates Their Head-to-Tail Association

    Takeshi Matsui;Masato Maeda;Yoshinori Doi;Shigenobu Yonemura

  • Involvement of ZO-1 in cadherin-based cell adhesion through its direct binding to alpha catenin and actin filaments.

    Masahiko Itoh;Akira Nagafuchi;Seiji Moroi;Shoichiro Tsukita

  • ZO-1 and ZO-2 Independently Determine Where Claudins Are Polymerized in Tight-Junction Strand Formation

    Kazuaki Umeda;Junichi Ikenouchi;Sayaka Katahira-Tayama;Kyoko Furuse

  • Occludin is a functional component of the tight junction

    Karin M. McCarthy;Ilze B. Skare;Michael C. Stankewich;Mikio Furuse

  • Tricellulin constitutes a novel barrier at tricellular contacts of epithelial cells

    Junichi Ikenouchi;Mikio Furuse;Kyoko Furuse;Hiroyuki Sasaki

  • Regulation of tight junctions during the epithelium-mesenchyme transition:direct repression of the gene expression of claudins/occludin by Snail

    Junichi Ikenouchi;Miho Matsuda;Mikio Furuse;Shoichiro Tsukita

  • Clostridium perfringens enterotoxin fragment removes specific claudins from tight junction strands: Evidence for direct involvement of claudins in tight junction barrier.

    Noriyuki Sonoda;Mikio Furuse;Hiroyuki Sasaki;Shigenobu Yonemura

Frequent Co-Authors

Mikio Furuse
Mikio Furuse The Graduate University for Advanced Studies, SOKENDAI
Sachiko Tsukita
Sachiko Tsukita Osaka University
Hiroyuki Sasaki
Hiroyuki Sasaki Jikei University School of Medicine
Akira Nagafuchi
Akira Nagafuchi Nara Medical University
Shigenobu Yonemura
Shigenobu Yonemura University of Tokushima
Toshio Hakoshima
Toshio Hakoshima Nara Institute of Science and Technology
Mitinori Saitou
Mitinori Saitou Kyoto University
Tetsuo Noda
Tetsuo Noda Japanese Foundation For Cancer Research
Toshiyuki Shimizu
Toshiyuki Shimizu University of Tokyo

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