D-Index & Metrics Best Publications
Molecular Biology
Japan
2023

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Molecular Biology D-index 147 Citations 79,516 534 World Ranking 51 National Ranking 4

Research.com Recognitions

Awards & Achievements

2023 - Research.com Molecular Biology in Japan Leader Award

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Phosphorylation

Kozo Kaibuchi mainly focuses on Cell biology, Rho-associated protein kinase, Molecular biology, Phosphorylation and Biochemistry. His Cell biology study incorporates themes from Cytoskeleton and Cell polarity. He has researched Rho-associated protein kinase in several fields, including Focal adhesion, Myosin light-chain kinase, Myosin and Internal medicine.

His work focuses on many connections between Molecular biology and other disciplines, such as GTP-binding protein regulators, that overlap with his field of interest in Peptide sequence and GTP'. His Phosphorylation research focuses on Lysophosphatidic acid and how it relates to Dorsal root ganglion. His GTPase research incorporates themes from Guanosine, RAC1 and RHOA.

His most cited work include:

  • Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters (4109 citations)
  • Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase) (2500 citations)
  • Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase). (1726 citations)

What are the main themes of his work throughout his whole career to date?

His primary scientific interests are in Cell biology, Biochemistry, Phosphorylation, Rho-associated protein kinase and Molecular biology. His study looks at the intersection of Cell biology and topics like Cytoskeleton with Actin. His work in Rho-associated protein kinase addresses issues such as RHOA, which are connected to fields such as Guanine nucleotide exchange factor.

His biological study spans a wide range of topics, including Complementary DNA and Myosin-light-chain phosphatase. His work in GTPase covers topics such as RAC1 which are related to areas like IQGAP1 and Cell adhesion. His research integrates issues of MAP2K7, Cyclin-dependent kinase 2 and MAP kinase kinase kinase in his study of Mitogen-activated protein kinase kinase.

He most often published in these fields:

  • Cell biology (59.77%)
  • Biochemistry (23.65%)
  • Phosphorylation (22.17%)

What were the highlights of his more recent work (between 2012-2021)?

  • Cell biology (59.77%)
  • Phosphorylation (22.17%)
  • Neuroscience (12.97%)

In recent papers he was focusing on the following fields of study:

His scientific interests lie mostly in Cell biology, Phosphorylation, Neuroscience, Kinase and Protein kinase A. His studies examine the connections between Cell biology and genetics, as well as such issues in Endocytosis, with regards to GTPase-activating protein. His Phosphorylation study focuses mostly on Protein phosphorylation and Rho-associated protein kinase.

His study on Neuroscience also encompasses disciplines like

  • Intracellular which connect with Neuronal polarity and Phosphoproteomics,
  • DISC1 that intertwine with fields like Prefrontal cortex, Internal medicine and Endocrinology. His study on Kinase is covered under Biochemistry. His Neurite study combines topics from a wide range of disciplines, such as Hippocampal formation, Axon and RHOA.

Between 2012 and 2021, his most popular works were:

  • Synaptic dysregulation in a human iPS cell model of mental disorders (351 citations)
  • Spatial regulation of VEGF receptor endocytosis in angiogenesis. (179 citations)
  • Pioneering Axons Regulate Neuronal Polarization in the Developing Cerebral Cortex (96 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Internal medicine

Kozo Kaibuchi mainly investigates Cell biology, Neuroscience, Phosphorylation, Intracellular and Endocytosis. As part of his studies on Cell biology, Kozo Kaibuchi often connects relevant areas like Cellular differentiation. His Cellular differentiation study also includes fields such as

  • Cellular neuroscience that intertwine with fields like Calcium signaling, Protein kinase A, Axon, RHOA and Neurite,
  • Stem cell that intertwine with fields like Molecular biology.

His Phosphorylation research includes themes of Epidermal growth factor receptor, Granule cell, Hippocampal formation, Microtubule and Kinase. His Intracellular research incorporates elements of Extracellular, HEK 293 cells, Downregulation and upregulation and Neuronal polarity. He has included themes like Cell adhesion, Cell adhesion molecule, Rho-associated protein kinase and Tyrosine phosphorylation in his Cerebral cortex study.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters

M Castagna;Y Takai;K Kaibuchi;K Sano.
Journal of Biological Chemistry (1982)

7367 Citations

Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)

Kazushi Kimura;Masaaki Ito;Mutsuki Amano;Kazuyasu Chihara.
Science (1996)

3512 Citations

Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase).

Mutsuki Amano;Masaaki Ito;Kazushi Kimura;Yuko Fukata.
Journal of Biological Chemistry (1996)

2533 Citations

Formation of Actin Stress Fibers and Focal Adhesions Enhanced by Rho-Kinase

Mutsuki Amano;Kazuyasu Chihara;Kazushi Kimura;Yuko Fukata.
Science (1997)

1352 Citations

Rho-associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein Rho

T. Matsui;M. Amano;T. Yamamoto;K. Chihara.
The EMBO Journal (1996)

1329 Citations

Regulation of the cytoskeleton and cell adhesion by the Rho family GTPases in mammalian cells.

K. Kaibuchi;S. Kuroda;M. Amano.
Annual Review of Biochemistry (1999)

1310 Citations

Rho–Rho-kinase pathway in smooth muscle contraction and cytoskeletal reorganization of non-muscle cells

Yuko Fukata;Kozo Kaibuchi;Mutsuki Amano.
Trends in Pharmacological Sciences (2001)

1070 Citations

Rho‐kinase/ROCK: A key regulator of the cytoskeleton and cell polarity

Mutsuki Amano;Masanori Nakayama;Kozo Kaibuchi.
Cytoskeleton (2010)

1050 Citations

Rho-Kinase Phosphorylates COOH-terminal Threonines of Ezrin/Radixin/Moesin (ERM) Proteins and Regulates Their Head-to-Tail Association

Takeshi Matsui;Masato Maeda;Yoshinori Doi;Shigenobu Yonemura.
Journal of Cell Biology (1998)

1008 Citations

GSK-3β Regulates Phosphorylation of CRMP-2 and Neuronal Polarity

Takeshi Yoshimura;Yoji Kawano;Nariko Arimura;Saeko Kawabata.
Cell (2005)

970 Citations

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