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Hiroaki Shimokawa

Hiroaki Shimokawa

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Medicine
Japan
2023

D-Index & Metrics

Medicine

D-Index
143
Citations
85882
World Ranking
1500
National Ranking
28

Research.com Recognitions

  • 2023 - Research.com Medicine in Japan Leader Award

Overview

Hiroaki Shimokawa is affiliated with Tohoku University in Japan and has a significant body of research in the field of medicine, with a strong focus on cardiology and cardiovascular medicine. Their work spans multiple subfields including cardiology and cardiovascular medicine, radiology, nuclear medicine and imaging, surgery, pulmonary and respiratory medicine, and physiology.

The primary research topics covered by Hiroaki Shimokawa include:

  • Cardiac Imaging and Diagnostics
  • Cardiovascular Function and Risk Factors
  • Coronary Interventions and Diagnostics
  • Heart Failure Treatment and Management
  • Lipoproteins and Cardiovascular Health
  • Cardiac Electrophysiology and Arrhythmias
  • Atrial Fibrillation Management and Outcomes

Among recent published papers, notable examples include:

  • Clinical characteristics and prognosis of patients with microvascular angina: an international and prospective cohort study by the Coronary Vasomotor Disorders International Study (COVADIS) Group, 2021, European Heart Journal
  • Treatment of coronary microvascular dysfunction, 2020, Cardiovascular Research
  • Assessment of Vascular Dysfunction in Patients Without Obstructive Coronary Artery Disease, 2020, JACC: Cardiovascular Interventions
  • JCS/CVIT/JCC 2023 Guideline Focused Update on Diagnosis and Treatment of Vasospastic Angina (Coronary Spastic Angina) and Coronary Microvascular Dysfunction, 2023, Circulation Journal
  • Coronary Microvascular Dysfunction, 2021, Arteriosclerosis Thrombosis and Vascular Biology

Hiroaki Shimokawa has collaborated frequently with a range of co-authors, including:

  • Satoshi Yasuda
  • Jun Takahashi
  • Kotaro Nochioka
  • Satoshi Miyata
  • Takashi Shiroto

The scientist's work has been published in several prominent academic journals, particularly:

  • European Heart Journal
  • International Journal of Cardiology
  • IJC Heart & Vasculature
  • SSRN Electronic Journal
  • Arteriosclerosis Thrombosis and Vascular Biology

This research spans a broad range of cardiovascular-related medical topics and diagnostic techniques, indicating integrative expertise in clinical cardiology. While no awards or book publications are recorded, the scope and frequent citations of their work reflect an active research profile within cardiovascular medicine.

Best Publications

  • Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease

    Paul M Ridker;Brendan M. Everett;Tom Thuren;Jean G. MacFadyen

  • Effect of interleukin-1β inhibition with canakinumab on incident lung cancer in patients with atherosclerosis: exploratory results from a randomised, double-blind, placebo-controlled trial

    Paul M Ridker;Jean G MacFadyen;Tom Thuren;Brendan M Everett

  • International Expert Consensus Document on Takotsubo Syndrome (Part I): Clinical Characteristics, Diagnostic Criteria, and Pathophysiology

    Jelena Rima Ghadri;Ilan Shor Wittstein;Abhiram Prasad;Scott Sharkey

  • Heart failure: preventing disease and death worldwide.

    Piotr P. Ponikowski;Stefan D. Anker;Khalid F. AlHabib;Martin R. Cowie

  • Endothelial dysfunction and vascular disease

    P. M. Vanhoutte;H. Shimokawa;E. H. C. Tang;M. Feletou

  • The importance of the hyperpolarizing mechanism increases as the vessel size decreases in endothelium-dependent relaxations in rat mesenteric circulation.

    Hiroaki Shimokawa;Hiroshi Yasutake;Koji Fujii;M. Owada

  • Endothelial dysfunction and vascular disease – a 30th anniversary update

    P. M. Vanhoutte;H. Shimokawa;M. Feletou;E. H. C. Tang

  • Relationship of C-reactive protein reduction to cardiovascular event reduction following treatment with canakinumab: a secondary analysis from the CANTOS randomised controlled trial

    Paul M Ridker;Jean G MacFadyen;Brendan M Everett;Peter Libby

  • Hydrogen peroxide is an endothelium-derived hyperpolarizing factor in mice

    Tetsuya Matoba;Hiroaki Shimokawa;Mikio Nakashima;Yoji Hirakawa

  • Double-blind and placebo-controlled study of the effectiveness and safety of extracorporeal cardiac shock wave therapy for severe angina pectoris.

    Yoku Kikuchi;Kenta Ito;Yoshitaka Ito;Takashi Shiroto

  • Extracorporeal cardiac shock wave therapy improves left ventricular remodeling after acute myocardial infarction in pigs

    Toyokazu Uwatoku;Kenta Ito;Kohtaro Abe;Keiji Oi

  • Cardiac shock wave therapy ameliorates left ventricular remodeling after myocardial ischemia-reperfusion injury in pigs in vivo.

    Yoshitaka Ito;Kenta Ito;Takashi Shiroto;Ryuji Tsuburaya

  • International Expert Consensus Document on Takotsubo Syndrome (Part II): Diagnostic Workup, Outcome, and Management

    Jelena Rima Ghadri;Ilan Shor Wittstein;Abhiram Prasad;Scott Sharkey

  • Rho-Kinase Is an Important Therapeutic Target in Cardiovascular Medicine

    Hiroaki Shimokawa;Akira Takeshita

  • Long-Term Inhibition of Rho-Kinase Suppresses Angiotensin II–Induced Cardiovascular Hypertrophy in Rats In Vivo Effect on Endothelial NAD(P)H Oxidase System

    Midoriko Higashi;Hiroaki Shimokawa;Tsuyoshi Hattori;Junko Hiroki

  • Suppression of Coronary Artery Spasm by the Rho-Kinase Inhibitor Fasudil in Patients With Vasospastic Angina

    Akihiro Masumoto;Masahiro Mohri;Hiroaki Shimokawa;Lemmy Urakami

  • International standardization of diagnostic criteria for microvascular angina.

    Peter Ong;Paolo G. Camici;John F. Beltrame;Filippo Crea

  • Rho-Kinase Mediates Hypoxia-Induced Downregulation of Endothelial Nitric Oxide Synthase

    Masao Takemoto;Jianxin Sun;Junko Hiroki;Hiroaki Shimokawa

  • Primary endothelial dysfunction: Atherosclerosis

    Hiroaki Shimokawa

  • Long-Term Treatment With a Rho-Kinase Inhibitor Improves Monocrotaline-Induced Fatal Pulmonary Hypertension in Rats

    Kohtaro Abe;Hiroaki Shimokawa;Keiko Morikawa;Toyokazu Uwatoku

Frequent Co-Authors

Akira Takeshita
Akira Takeshita Kyushu University
Kensuke Egashira
Kensuke Egashira Kyushu University
Nobuyuki Yanagihara
Nobuyuki Yanagihara University of Occupational and Environmental Health Japan
Hisao Ogawa
Hisao Ogawa Kumamoto University
Paul M. Vanhoutte
Paul M. Vanhoutte University of Hong Kong
Akira Ito
Akira Ito Nagoya University
Kozo Kaibuchi
Kozo Kaibuchi Nagoya University
Kenji Sunagawa
Kenji Sunagawa Kyushu University
Hiroyuki Tsutsui
Hiroyuki Tsutsui Kyushu University
Hiroshi Kanai
Hiroshi Kanai Tohoku University

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