World's Best Scientists 2026 revealed!
Kensuke Egashira

Kensuke Egashira

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Medicine
Japan
2023

D-Index & Metrics

Medicine

D-Index
111
Citations
38902
World Ranking
5390
National Ranking
116

Research.com Recognitions

  • 2023 - Research.com Medicine in Japan Leader Award

Overview

Kensuke Egashira is affiliated with Kyushu University in Japan and has contributed to research primarily in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work intersects multiple subfields, including Surgery, Molecular Biology, Pulmonary and Respiratory Medicine, Molecular Medicine, and Cancer Research.

The scientist's research topics encompass a range of biomedical and molecular areas. Key topics of focus include:

  • Curcumin's Biomedical Applications
  • Aortic aneurysm repair treatments
  • Lipoproteins and Cardiovascular Health
  • Mitochondrial Function and Pathology
  • ATP Synthase and ATPases Research
  • Autophagy in Disease and Therapy
  • Nanoparticle-Based Drug Delivery

Egashira's most recent papers illustrate involvement in vascular biology, nanoparticle drug delivery, and cardiovascular disease models. Selected publications are:

  • Macrophage (Drp1) Dynamin-Related Protein 1 Accelerates Intimal Thickening After Vascular Injury, 2020, Arteriosclerosis Thrombosis and Vascular Biology
  • Nanoparticle-Mediated Delivery of 2-Deoxy-D-Glucose Induces Antitumor Immunity and Cytotoxicity in Liver Tumors in Mice, 2020, Cellular and Molecular Gastroenterology and Hepatology
  • Nanoparticle-Mediated Simultaneous Targeting of Mitochondrial Injury and Inflammation Attenuates Myocardial Ischemia-Reperfusion Injury, 2021, Journal of the American Heart Association
  • Nanoparticle-Mediated Delivery of Pitavastatin to Monocytes/Macrophages Inhibits Angiotensin II-Induced Abdominal Aortic Aneurysm Formation in Apoe−/− Mice, 2021, Journal of Atherosclerosis and Thrombosis
  • Therapeutic Arteriogenesis/Angiogenesis for Peripheral Arterial Disease by Nanoparticle-Mediated Delivery of Pitavastatin into Vascular Endothelial Cells, 2020, Annals of Vascular Diseases

The frequent venues of publication include:

  • Journal of Atherosclerosis and Thrombosis
  • Arteriosclerosis Thrombosis and Vascular Biology
  • Cellular and Molecular Gastroenterology and Hepatology
  • Journal of the American Heart Association
  • Annals of Vascular Diseases

Egashira regularly collaborates with several coauthors, among them:

  • Kaku Nakano
  • Tetsuya Matoba
  • Hiroyuki Tsutsui
  • Jun-ichiro Koga
  • Ryuta Umezu

Best Publications

  • MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity

    Hajime Kanda;Sanshiro Tateya;Yoshikazu Tamori;Ko Kotani;Ko Kotani

  • The importance of the hyperpolarizing mechanism increases as the vessel size decreases in endothelium-dependent relaxations in rat mesenteric circulation.

    Hiroaki Shimokawa;Hiroshi Yasutake;Koji Fujii;M. Owada

  • Transforming Growth Factor-β Function Blocking Prevents Myocardial Fibrosis and Diastolic Dysfunction in Pressure-Overloaded Rats

    Fumitaka Kuwahara;Hisashi Kai;Keisuke Tokuda;Mamiko Kai

  • Mitochondrial Electron Transport Complex I Is a Potential Source of Oxygen Free Radicals in the Failing Myocardium

    Tomomi Ide;Hiroyuki Tsutsui;Shintaro Kinugawa;Hideo Utsumi

  • Reduction in serum cholesterol with pravastatin improves endothelium-dependent coronary vasomotion in patients with hypercholesterolemia.

    Kensuke Egashira;Yoshitaka Hirooka;Hisashi Kai;Masaru Sugimachi

  • Evidence of Impaired Endothelium-Dependent Coronary Vasodilatation in Patients with Angina Pectoris and Normal Coronary Angiograms

    Kensuke Egashira;Tetsuzi Inou;Yoshitaka Hirooka;Akira Yamada

  • Endogenous Drp1 Mediates Mitochondrial Autophagy and Protects the Heart Against Energy Stress

    Yoshiyuki Ikeda;Akihiro Shirakabe;Yasuhiro Maejima;Peiyong Zhai

  • Bone marrow monocyte lineage cells adhere on injured endothelium in a monocyte chemoattractant protein-1-dependent manner and accelerate reendothelialization as endothelial progenitor cells

    Soichiro Fujiyama;Katsuya Amano;Kazutaka Uehira;Masayuki Yoshida

  • Effects of age on endothelium-dependent vasodilation of resistance coronary artery by acetylcholine in humans.

    Kensuke Egashira;Tetsuzi Inou;Yoshitaka Hirooka;Hisashi Kai

  • Direct Evidence for Increased Hydroxyl Radicals Originating From Superoxide in the Failing Myocardium

    Tomomi Ide;Hiroyuki Tsutsui;Shintaro Kinugawa;Nobuhiro Suematsu

  • Rho-kinase-mediated pathway induces enhanced myosin light chain phosphorylations in a swine model of coronary artery spasm.

    Hiroaki Shimokawa;Minoru Seto;Naoki Katsumata;Mutsuki Amano

  • Important Role of Tissue Angiotensin-converting Enzyme Activity in the Pathogenesis of Coronary Vascular and Myocardial Structural Changes Induced by Long-Term Blockade of Nitric Oxide Synthesis in Rats

    Masao Takemoto;Kensuke Egashira;Makoto Usui;Kohtaro Numaguchi

  • Drp1-Dependent Mitochondrial Autophagy Plays a Protective Role Against Pressure Overload-Induced Mitochondrial Dysfunction and Heart Failure.

    Akihiro Shirakabe;Peiyong Zhai;Yoshiyuki Ikeda;Yoshiyuki Ikeda;Toshiro Saito

  • Gene Transfer of Stromal Cell–Derived Factor-1α Enhances Ischemic Vasculogenesis and Angiogenesis via Vascular Endothelial Growth Factor/Endothelial Nitric Oxide Synthase–Related Pathway: Next-Generation Chemokine Therapy for Therapeutic Neovascularization

    Ken Ichi Hiasa;Minako Ishibashi;Kisho Ohtani;Shujiro Inoue

  • Impaired coronary blood flow response to acetylcholine in patients with coronary risk factors and proximal atherosclerotic lesions.

    K Egashira;T Inou;Y Hirooka;A Yamada

  • Importance of endothelium-derived hyperpolarizing factor in human arteries.

    Lemmy Urakami-Harasawa;Hiroaki Shimokawa;Mikio Nakashima;Kensuke Egashira

  • Angina pectoris caused by coronary microvascular spasm

    Masahiro Mohri;Masamichi Koyanagi;Kensuke Egashira;Hirofumi Tagawa

  • Chronic treatment with interleukin-1 beta induces coronary intimal lesions and vasospastic responses in pigs in vivo. The role of platelet-derived growth factor.

    Hiroaki Shimokawa;Akira Ito;Yoshihiro Fukumoto;Toshiaki Kadokami

  • Hypertensive Myocardial Fibrosis and Diastolic Dysfunction: Another Model of Inflammation?

    Fumitaka Kuwahara;Hisashi Kai;Keisuke Tokuda;Motohiro Takeya

  • Pioglitazone, a Peroxisome Proliferator–Activated Receptor-γ Agonist, Attenuates Left Ventricular Remodeling and Failure After Experimental Myocardial Infarction

    Tetsuya Shiomi;Hiroyuki Tsutsui;Shunji Hayashidani;Nobuhiro Suematsu

Frequent Co-Authors

Akira Takeshita
Akira Takeshita Kyushu University
Kenji Sunagawa
Kenji Sunagawa Kyushu University
Hiroaki Shimokawa
Hiroaki Shimokawa Tohoku University
Hiroyuki Tsutsui
Hiroyuki Tsutsui Kyushu University
Hitonobu Tomoike
Hitonobu Tomoike National Cardiovascular Research Center
Akira Ito
Akira Ito Nagoya University
Ryuichi Morishita
Ryuichi Morishita Osaka University
Stuart B. Goodman
Stuart B. Goodman Stanford University
Israel F. Charo
Israel F. Charo University of California, San Francisco
Motohiro Takeya
Motohiro Takeya Kumamoto Health Science University

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