H-Index & Metrics Best Publications

H-Index & Metrics

Discipline name H-index Citations Publications World Ranking National Ranking
Medicine D-index 102 Citations 41,309 242 World Ranking 3372 National Ranking 1927

Research.com Recognitions

Awards & Achievements

Member of the Association of American Physicians

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Internal medicine
  • Enzyme

James K. Liao mostly deals with Internal medicine, Endocrinology, Pharmacology, Cell biology and Nitric oxide. The Internal medicine study combines topics in areas such as Intracellular, Superoxide and Bioinformatics. Endocrinology is closely attributed to Protein kinase B in his research.

His studies in Pharmacology integrate themes in fields like Inflammation, Reductase, Cholesterol and Enzyme inhibitor. His Cell biology research is multidisciplinary, relying on both Endothelial stem cell and Angiogenesis. His studies deal with areas such as Tumor necrosis factor alpha, Molecular biology and Endothelium as well as Nitric oxide.

His most cited work include:

  • Upregulation of Endothelial Nitric Oxide Synthase by HMG CoA Reductase Inhibitors (1702 citations)
  • Nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines. (1551 citations)
  • PLEIOTROPIC EFFECTS OF STATINS (1463 citations)

What are the main themes of his work throughout his whole career to date?

The scientist’s investigation covers issues in Internal medicine, Endocrinology, Cell biology, Pharmacology and Cardiology. James K. Liao has researched Internal medicine in several fields, including Kinase and Rho-associated protein kinase. In his study, PI3K/AKT/mTOR pathway is inextricably linked to Protein kinase B, which falls within the broad field of Endocrinology.

His biological study spans a wide range of topics, including Endothelial stem cell and Biochemistry. His work carried out in the field of Pharmacology brings together such families of science as Inflammation, Downregulation and upregulation, Ischemia and HMG-CoA reductase. His work focuses on many connections between Cholesterol and other disciplines, such as Statin, that overlap with his field of interest in Pleiotropy.

He most often published in these fields:

  • Internal medicine (51.17%)
  • Endocrinology (35.51%)
  • Cell biology (15.93%)

What were the highlights of his more recent work (between 2015-2021)?

  • Internal medicine (51.17%)
  • Cardiology (14.10%)
  • Endocrinology (35.51%)

In recent papers he was focusing on the following fields of study:

James K. Liao mainly investigates Internal medicine, Cardiology, Endocrinology, Heart failure and Emergency medicine. Internal medicine and Oncology are frequently intertwined in his study. His research investigates the connection between Cardiology and topics such as Stroke that intersect with problems in Platelet and Ischemia.

James K. Liao combines subjects such as Actin cytoskeleton and Rho-associated protein kinase with his study of Endocrinology. His Rho-associated protein kinase study also includes

  • Lesion which intersects with area such as Simvastatin, Pharmacology and Disease,
  • Pulmonary fibrosis and Cancer research most often made with reference to ROCK1. His study in Enos is interdisciplinary in nature, drawing from both Sodium nitroprusside and Neuroprotection.

Between 2015 and 2021, his most popular works were:

  • Pleiotropic Effects of Statins on the Cardiovascular System. (375 citations)
  • Elevated Angiopoietin-2 Level in Patients With Continuous-Flow Left Ventricular Assist Devices Leads to Altered Angiogenesis and Is Associated With Higher Nonsurgical Bleeding. (78 citations)
  • Rho Kinases and Cardiac Remodeling (52 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Internal medicine
  • Enzyme

His main research concerns Internal medicine, Endocrinology, Rho-associated protein kinase, Actin cytoskeleton and Stroke. His research integrates issues of Placebo, Fasudil and Cardiology in his study of Internal medicine. His study in Endocrinology concentrates on Cholesterol, Diastole and Angiotensin II.

James K. Liao has included themes like Statin and Lesion in his Rho-associated protein kinase study. His Lesion research incorporates elements of Simvastatin, Pharmacology and Disease. His Stroke research is multidisciplinary, incorporating elements of Pleiotropy, Nicotinamide adenine dinucleotide phosphate, Platelet, Tissue plasminogen activator and Morris water navigation task.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Upregulation of Endothelial Nitric Oxide Synthase by HMG CoA Reductase Inhibitors

Ulrich Laufs;Vito La Fata;Jorge Plutzky;James K. Liao.
Circulation (1998)

2764 Citations

PLEIOTROPIC EFFECTS OF STATINS

James K. Liao;Ulrich Laufs.
Annual Review of Pharmacology and Toxicology (2005)

2346 Citations

Nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines.

R De Caterina;Peter Libby;H B Peng;V J Thannickal.
Journal of Clinical Investigation (1995)

2181 Citations

Pleiotropic Effects of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibitors

Masao Takemoto;James K. Liao.
Arteriosclerosis, Thrombosis, and Vascular Biology (2001)

1908 Citations

Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase

Tommaso Simoncini;Ali Hafezi-Moghadam;Derek P. Brazil;Klaus Ley.
Nature (2000)

1623 Citations

Post-transcriptional Regulation of Endothelial Nitric Oxide Synthase mRNA Stability by Rho GTPase

Ulrich Laufs;James K. Liao.
Journal of Biological Chemistry (1998)

1504 Citations

Anti-inflammatory Properties of Cytochrome P450 Epoxygenase-Derived Eicosanoids

Koichi Node;Yuqing Huo;Xiulu Ruan;Baichun Yang.
Science (1999)

1269 Citations

Stroke protection by 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors mediated by endothelial nitric oxide synthase

Matthias Endres;Ulrich Laufs;Zhihong Huang;Tadashi Nakamura.
Proceedings of the National Academy of Sciences of the United States of America (1998)

1188 Citations

Induction and Stabilization of IκBα by Nitric Oxide Mediates Inhibition of NF-κB

Hai-Bing Peng;Peter Libby;James K. Liao.
Journal of Biological Chemistry (1995)

1030 Citations

OXIDIZED LOW-DENSITY LIPOPROTEIN DECREASES THE EXPRESSION OF ENDOTHELIAL NITRIC OXIDE SYNTHASE

James K. Liao;Wee Soo Shin;Wen Yee Lee;Stephen L. Clark.
Journal of Biological Chemistry (1995)

803 Citations

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