D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Chemistry D-index 125 Citations 50,391 814 World Ranking 215 National Ranking 113
Medicine D-index 119 Citations 45,125 753 World Ranking 2217 National Ranking 1287
Biology and Biochemistry D-index 127 Citations 50,759 767 World Ranking 330 National Ranking 230

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Gene
  • Organic chemistry

John R. Falck mainly investigates Biochemistry, Arachidonic acid, Internal medicine, Endocrinology and Cytochrome P450. His Biochemistry research is multidisciplinary, incorporating elements of Molecular biology and Stereochemistry. The various areas that John R. Falck examines in his Arachidonic acid study include Metabolite, Microsome and Metabolism.

His work on Endocrinology is being expanded to include thematically relevant topics such as Cyclooxygenase. His Epoxygenase study incorporates themes from Epoxide hydrolase 2 and Pharmacology. His Kidney research is multidisciplinary, relying on both Vasoconstriction and Vascular smooth muscle.

His most cited work include:

  • Role of Substrates and Products of PI 3-kinase in Regulating Activation of Rac-Related Guanosine Triphosphatases by Vav (745 citations)
  • Cytochrome P450 and arachidonic acid bioactivation: molecular and functional properties of the arachidonate monooxygenase (480 citations)
  • Lysine propionylation and butyrylation are novel post-translational modifications in histones. (430 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of study are Internal medicine, Endocrinology, Biochemistry, Arachidonic acid and Stereochemistry. His Internal medicine study frequently draws connections to other fields, such as 20-Hydroxyeicosatetraenoic acid. His Endocrinology study focuses mostly on Vasodilation, Angiotensin II, Endothelium, Vascular smooth muscle and Nitric oxide.

Biochemistry is closely attributed to Pharmacology in his research. He interconnects Metabolite, Cytochrome and Cytochrome P450, Metabolism in the investigation of issues within Arachidonic acid. John R. Falck focuses mostly in the field of Stereochemistry, narrowing it down to matters related to Organic chemistry and, in some cases, Medicinal chemistry.

He most often published in these fields:

  • Internal medicine (29.38%)
  • Endocrinology (28.10%)
  • Biochemistry (26.26%)

What were the highlights of his more recent work (between 2013-2021)?

  • Internal medicine (29.38%)
  • Endocrinology (28.10%)
  • Epoxyeicosatrienoic acid (13.41%)

In recent papers he was focusing on the following fields of study:

John R. Falck focuses on Internal medicine, Endocrinology, Epoxyeicosatrienoic acid, Pharmacology and Blood pressure. His study brings together the fields of Arachidonic acid and Internal medicine. The study incorporates disciplines such as Vasoconstriction, Inflammation and Endothelial stem cell in addition to Arachidonic acid.

Kidney, Angiotensin II, Vasodilation, Epoxygenase and Cytochrome P450 are the core of his Endocrinology study. His Cytochrome P450 study is concerned with the field of Biochemistry as a whole. His research in Epoxyeicosatrienoic acid intersects with topics in Heart failure, Kidney disease, Radiation Nephropathy, Receptor and Myocardial infarction.

Between 2013 and 2021, his most popular works were:

  • Direct Stereospecific Synthesis of Unprotected N-H and N-Me Aziridines from Olefins (116 citations)
  • Dirhodium-catalyzed C-H arene amination using hydroxylamines. (85 citations)
  • QseC Inhibitors as an Antivirulence Approach for Gram-Negative Pathogens (80 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Gene
  • Organic chemistry

John R. Falck mostly deals with Endocrinology, Internal medicine, Epoxyeicosatrienoic acid, Cytochrome P450 and Kidney. His studies deal with areas such as Wnt signaling pathway, SIRT3, Downregulation and upregulation and 20-Hydroxyeicosatetraenoic acid as well as Internal medicine. The Epoxyeicosatrienoic acid study combines topics in areas such as Endothelial stem cell, Agonist, Receptor, Epoxygenase and Vasodilation.

Epoxygenase is a subfield of Arachidonic acid that John R. Falck explores. As part of one scientific family, he deals mainly with the area of Cytochrome P450, narrowing it down to issues related to the Epoxide hydrolase 2, and often Cell biology, Inflammation, Tetrazole, Carboxylate and Epoxide. John R. Falck combines subjects such as Oxidative phosphorylation and Biochemistry with his study of Cell biology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Role of Substrates and Products of PI 3-kinase in Regulating Activation of Rac-Related Guanosine Triphosphatases by Vav

Jaewon Han;Katherine Luby-Phelps;Balaka Das;Xiaodong Shu.
Science (1998)

1013 Citations

Cytochrome P450 and arachidonic acid bioactivation: molecular and functional properties of the arachidonate monooxygenase

Jorge H. Capdevila;John R. Falck;Raymond C. Harris.
Journal of Lipid Research (2000)

659 Citations

Lysine propionylation and butyrylation are novel post-translational modifications in histones.

Yue Chen;Robert Sprung;Yi Tang;Haydn Ball.
Molecular & Cellular Proteomics (2007)

631 Citations

High Affinity Binding of Inositol Phosphates and Phosphoinositides to the Pleckstrin Homology Domain of RAC/Protein Kinase B and Their Influence on Kinase Activity*

Matthias Frech;Mirjana Andjelkovic;Evan Ingley;K. Kishta Reddy.
Journal of Biological Chemistry (1997)

551 Citations

MOLECULAR CLONING AND EXPRESSION OF CYP2J2, A HUMAN CYTOCHROME P450 ARACHIDONIC ACID EPOXYGENASE HIGHLY EXPRESSED IN HEART

Shu Wu;Cindy R. Moomaw;Kenneth B. Tomer;John R. Falck.
Journal of Biological Chemistry (1996)

545 Citations

Targeting QseC Signaling and Virulence for Antibiotic Development

David A. Rasko;Cristiano G. Moreira;De Run Li;Nicola C. Reading.
Science (2008)

528 Citations

Human cytochromes P450

Julia A Hasler;Ronald Estabrook;Michael Murray;Irina Pikuleva.
Molecular Aspects of Medicine (1999)

428 Citations

Cytochrome P450 and the arachidonate cascade.

Jorge H. Capdevila;J R Falck;Ronald W. Estabrook.
The FASEB Journal (1992)

417 Citations

Structure-activity analysis of the interaction of curacin A, the potent colchicine site antimitotic agent, with tubulin and effects of analogs on the growth of MCF-7 breast cancer cells.

Pascal Verdier-Pinard;Jing Yu Lai;Hae Dong Yoo;Jurong Yu.
Molecular Pharmacology (1998)

389 Citations

A tagging-via-substrate technology for detection and proteomics of farnesylated proteins

Yoonjung Kho;Sung Chan Kim;Chen Jiang;Deb Barma.
Proceedings of the National Academy of Sciences of the United States of America (2004)

375 Citations

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