Christophe Morisseau

Overview

Best Publications

• Soluble Epoxide Hydrolase Regulates Hydrolysis of Vasoactive Epoxyeicosatrienoic Acids

  Zhigang Yu;Fengyun Xu;Linn M. Huse;Christophe Morisseau

  571
  Citations

• Epoxide hydrolases: Mechanisms, inhibitor designs, and biological roles

  Christophe Morisseau;Bruce D. Hammock

  559
  Citations

• Impact of Soluble Epoxide Hydrolase and Epoxyeicosanoids on Human Health

  Christophe Morisseau;Bruce D. Hammock

  555
  Citations

• Epoxide hydrolases: their roles and interactions with lipid metabolism.

  John W. Newman;Christophe Morisseau;Bruce D. Hammock

  523
  Citations

• Inhibition of mycolic acid transport across the Mycobacterium tuberculosis plasma membrane

  Anna E Grzegorzewicz;Ha Pham;Vijay A K B Gundi;Michael S Scherman

  495
  Citations

• Soluble Epoxide Hydrolase Inhibition Lowers Arterial Blood Pressure in Angiotensin II Hypertension

  John D. Imig;Xueying Zhao;Jorge H. Capdevila;Christophe Morisseau

  466
  Citations

• Modulation of the Ca2 Permeable Cation Channel TRPV4 by Cytochrome P450 Epoxygenases in Vascular Endothelium

  Joris Vriens;Grzegorz Owsianik;B Fisslthaler;M Suzuki

  429
  Citations

• The antiinflammatory effect of laminar flow: The role of PPARγ, epoxyeicosatrienoic acids, and soluble epoxide hydrolase

  Yi Liu;Yingjia Zhang;Kara Schmelzer;Tzong Shyuan Lee

  361
  Citations

• Potent urea and carbamate inhibitors of soluble epoxide hydrolases

  Christophe Morisseau;Marvin H. Goodrow;Deanna Dowdy;Jiang Zheng

  302
  Citations

• Pathways of Epoxyeicosatrienoic Acid Metabolism in Endothelial Cells IMPLICATIONS FOR THE VASCULAR EFFECTS OF SOLUBLE EPOXIDE HYDROLASE INHIBITION

  Xiang Fang;Terry L. Kaduce;Neal Lee Weintraub;Shawn Harmon

  294
  Citations

• Detoxification of environmental mutagens and carcinogens: structure, mechanism, and evolution of liver epoxide hydrolase

  Maria A. Argiriadi;Christophe Morisseau;Bruce D. Hammock;David W. Christianson

  283
  Citations

• Orally bioavailable potent soluble epoxide hydrolase inhibitors.

  Sung Hee Hwang;Hsing-Ju Tsai;Jun-Yan Liu;Christophe Morisseau

  280
  Citations

• Naturally occurring monoepoxides of eicosapentaenoic acid and docosahexaenoic acid are bioactive antihyperalgesic lipids

  Christophe Morisseau;Bora Inceoglu;Kara Schmelzer;Hsing Ju Tsai

  268
  Citations

• Epoxyeicosatrienoic Acids Regulate Trp Channel–Dependent Ca2+ Signaling and Hyperpolarization in Endothelial Cells

  Ingrid Fleming;Alexandra Rueben;Riidiger Popp;Beate Fisslthaler

  256
  Citations

• The Soluble Epoxide Hydrolase Encoded by EPXH2 Is a Bifunctional Enzyme With Novel Lipid Phosphate Phosphatase Activity

  John W. Newman;Christophe Morisseau;Todd R. Harris;Bruce D. Hammock

  255
  Citations

• Structural refinement of inhibitors of urea-based soluble epoxide hydrolases.

  Christophe Morisseau;Marvin H. Goodrow;John W. Newman;Craig E. Wheelock

  237
  Citations

• Structure of human epoxide hydrolase reveals mechanistic inferences on bifunctional catalysis in epoxide and phosphate ester hydrolysis

  German A. Gomez;Christophe Morisseau;Bruce D. Hammock;David W. Christianson

  237
  Citations

• Design, synthesis, and biological activity of 1,3-disubstituted ureas as potent inhibitors of the soluble epoxide hydrolase of increased water solubility.

  In Hae Kim;Christophe Morisseau;Takaho Watanabe;Bruce D. Hammock

  234
  Citations

• Soluble epoxide hydrolase inhibition reveals novel biological functions of epoxyeicosatrienoic acids (EETs).

  Bora Inceoglu;Kara R. Schmelzer;Christophe Morisseau;Steve L. Jinks

  229
  Citations

• 1-Aryl-3-(1-acylpiperidin-4-yl)urea Inhibitors of Human and Murine Soluble Epoxide Hydrolase: Structure-Activity Relationships, Pharmacokinetics and Reduction of Inflammatory Pain

  Tristan E. Rose;Christophe Morisseau;Jun Yan Liu;Bora Inceoglu

  224
  Citations