World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
89
Citations
26145
World Ranking
2203
National Ranking
789

David W. Christianson publication distribution in Chemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Chemistry in 2026. The highlighted bar marks where David W. Christianson sits on this spectrum.

61–80 publications: 66 scientists 81–100 publications: 302 scientists 101–120 publications: 623 scientists 121–140 publications: 918 scientists 141–160 publications: 1,218 scientists 161–180 publications: 1,350 scientists 181–200 publications: 1,344 scientists 201–220 publications: 1,281 scientists 221–240 publications: 1,216 scientists 241–260 publications: 1,100 scientists 261–280 publications: 979 scientists 281–300 publications: 939 scientists 301–320 publications: 764 scientists 321–340 publications: 643 scientists 341–360 publications: 628 scientists 361–380 publications: 522 scientists 381–400 publications: 459 scientists 401–420 publications: 397 scientists 421–440 publications: 327 scientists 441–460 publications: 270 scientists 461–480 publications: 265 scientists 481–500 publications: 252 scientists 501–520 publications: 201 scientists 521–540 publications: 185 scientists 541–560 publications: 148 scientists 561–580 publications: 148 scientists 581–600 publications: 132 scientists 601–620 publications: 114 scientists 621–640 publications: 104 scientists 641–660 publications: 91 scientists 661–680 publications: 92 scientists 681–700 publications: 73 scientists 701–720 publications: 57 scientists 721–740 publications: 54 scientists 741–760 publications: 67 scientists 761–780 publications: 45 scientists 781–800 publications: 46 scientists 801–820 publications: 39 scientists 821–840 publications: 32 scientists 841–860 publications: 36 scientists 861–880 publications: 29 scientists 881–900 publications: 26 scientists 901–920 publications: 24 scientists 921–940 publications: 14 scientists 941–960 publications: 23 scientists 961–980 publications: 28 scientists 981–1,000 publications: 15 scientists 1,001–1,020 publications: 29 scientists 1,021–1,040 publications: 12 scientists 1,041–1,060 publications: 19 scientists 1,061–1,080 publications: 12 scientists 1,081–1,100 publications: 6 scientists 1,101–1,120 publications: 8 scientists 1,121–1,140 publications: 12 scientists 1,141–1,160 publications: 5 scientists 1,161–1,180 publications: 6 scientists 1,181–1,200 publications: 14 scientists 1,201–1,220 publications: 7 scientists 1,221–1,240 publications: 2 scientists 1,241–1,260 publications: 6 scientists 1,261–1,280 publications: 4 scientists 1,281–1,294 publications: 6 scientists 1,295+ publications: 100 scientists
61 publications 1,295+

This scientist: 601 publications — 93rd percentile

93% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,295 publications or more.

David W. Christianson D-index placement in Chemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Chemistry scientists ranked by Research.com in 2026. The highlighted bar marks where David W. Christianson sits on this spectrum.

40–41 D-Index: 289 scientists 42–43 D-Index: 612 scientists 44–45 D-Index: 808 scientists 46–47 D-Index: 776 scientists 48–49 D-Index: 835 scientists 50–51 D-Index: 861 scientists 52–53 D-Index: 872 scientists 54–55 D-Index: 933 scientists 56–57 D-Index: 1,051 scientists 58–59 D-Index: 930 scientists 60–61 D-Index: 882 scientists 62–63 D-Index: 834 scientists 64–65 D-Index: 731 scientists 66–67 D-Index: 775 scientists 68–69 D-Index: 683 scientists 70–71 D-Index: 646 scientists 72–73 D-Index: 561 scientists 74–75 D-Index: 501 scientists 76–77 D-Index: 437 scientists 78–79 D-Index: 388 scientists 80–81 D-Index: 354 scientists 82–83 D-Index: 292 scientists 84–85 D-Index: 275 scientists 86–87 D-Index: 254 scientists 88–89 D-Index: 235 scientists 90–91 D-Index: 185 scientists 92–93 D-Index: 192 scientists 94–95 D-Index: 155 scientists 96–97 D-Index: 163 scientists 98–99 D-Index: 125 scientists 100–101 D-Index: 105 scientists 102–103 D-Index: 105 scientists 104–105 D-Index: 112 scientists 106–107 D-Index: 88 scientists 108–109 D-Index: 68 scientists 110–111 D-Index: 69 scientists 112–113 D-Index: 65 scientists 114–115 D-Index: 79 scientists 116–117 D-Index: 61 scientists 118–119 D-Index: 44 scientists 120–121 D-Index: 37 scientists 122–123 D-Index: 40 scientists 124–125 D-Index: 33 scientists 126–127 D-Index: 26 scientists 128–129 D-Index: 34 scientists 130–131 D-Index: 35 scientists 132–133 D-Index: 25 scientists 134–135 D-Index: 27 scientists 136–137 D-Index: 17 scientists 138–139 D-Index: 16 scientists 140–141 D-Index: 20 scientists 142–143 D-Index: 20 scientists 144–145 D-Index: 15 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 9 scientists 150–151 D-Index: 16 scientists 152–153 D-Index: 11 scientists 154–155 D-Index: 9 scientists 156–157 D-Index: 3 scientists 158 D-Index: 3 scientists 159+ D-Index: 98 scientists
40 D-Index 159+

This scientist: 89 D-Index — 88th percentile

88% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 159 D-Index or more.

Research.com Recognitions

  • 2006 - Fellow of John Simon Guggenheim Memorial Foundation
  • 1992 - Fellow of Alfred P. Sloan Foundation

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Gene
  • Amino acid

His main research concerns Stereochemistry, Biochemistry, Active site, Protein structure and Hydrolase. His Stereochemistry research incorporates elements of Lyase, Cyclase, ATP synthase, Enzyme and Carbocation. He combines subjects such as Site-directed mutagenesis and Farnesyl diphosphate synthase with his study of Active site.

The Protein structure study combines topics in areas such as Metalloprotein, Structural biology, Biophysics and Histidine. The concepts of his Hydrolase study are interwoven with issues in Structure–activity relationship, Epoxide, Hydrogen bond, Acetyllysine and Binding site. His study looks at the relationship between Binding site and fields such as Molecule, as well as how they intersect with chemical problems.

His most cited work include:

  • Structural biology and chemistry of the terpenoid cyclases. (527 citations)
  • HDAC8 mutations in Cornelia de Lange syndrome affect the cohesin acetylation cycle (383 citations)
  • Crystal structure of pentalenene synthase: Mechanistic insights on terpenoid cyclization reactions in biology (336 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of investigation include Stereochemistry, Active site, Biochemistry, Crystal structure and Arginase. His Stereochemistry study integrates concerns from other disciplines, such as Hydrolase, Lyase, Enzyme, Protein structure and Binding site. His Lyase study which covers Cyclase that intersects with Terpenoid.

In his research on the topic of Active site, Side chain is strongly related with Carbonic anhydrase II. His study in Crystal structure is interdisciplinary in nature, drawing from both Substrate, Danio and HDAC10. David W. Christianson has researched Arginase in several fields, including Nitric oxide synthase, Nitric oxide and Manganese.

He most often published in these fields:

  • Stereochemistry (60.85%)
  • Active site (26.76%)
  • Biochemistry (26.20%)

What were the highlights of his more recent work (between 2017-2021)?

  • Stereochemistry (60.85%)
  • HDAC10 (6.48%)
  • Crystal structure (23.94%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Stereochemistry, HDAC10, Crystal structure, HDAC6 and Danio. His work deals with themes such as Cyclase, Catalysis, Active site, Molecule and Prenyltransferase, which intersect with Stereochemistry. David W. Christianson is investigating Active site as part of his Biochemistry and Enzyme and Active site study.

His HDAC6 study combines topics from a wide range of disciplines, such as Selectivity, Structure–activity relationship, Isozyme and Zebrafish. His Isozyme research includes elements of Protein structure and Epigenetics. His research investigates the connection between Danio and topics such as Cell biology that intersect with problems in Mutant.

Between 2017 and 2021, his most popular works were:

  • Synthesis and Biological Investigation of Phenothiazine-Based Benzhydroxamic Acids as Selective Histone Deacetylase 6 Inhibitors (37 citations)
  • Histone Deacetylase 6-Selective Inhibitors and the Influence of Capping Groups on Hydroxamate-Zinc Denticity (36 citations)
  • Discovery of the First-in-Class Dual Histone Deacetylase-Proteasome Inhibitor. (29 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Gene
  • Amino acid

David W. Christianson spends much of his time researching HDAC6, Stereochemistry, Active site, Isozyme and Selectivity. His studies in Stereochemistry integrate themes in fields like Amino acid, Plasma protein binding, Hydrolase, HDAC10 and Protein structure. His Hydrolase study incorporates themes from Ketone, Binding site and Binding selectivity.

His research integrates issues of Carbocation, Lyase, Cyclase and Organic synthesis in his study of Protein structure. Active site connects with themes related to Stereospecificity in his study. His Isozyme research is under the purview of Biochemistry.

Best Publications

  • Structural and Chemical Biology of Terpenoid Cyclases.

    David W. Christianson

  • Structural biology and chemistry of the terpenoid cyclases.

    David W. Christianson

  • Carbonic Anhydrase: Evolution of the Zinc Binding Site by Nature and by Design

    David W. Christianson;Carol A. Fierke

  • Structural biology of zinc.

    David W. Christianson

  • Crystal structure of pentalenene synthase: Mechanistic insights on terpenoid cyclization reactions in biology

    Charles A. Lesburg;Guangzhi Zhai;Guangzhi Zhai;David E. Cane;David E. Cane;David W. Christianson;David W. Christianson

  • Structure of a unique binuclear manganese cluster in arginase

    Zoltan F. Kanyo;Laura R. Scolnick;David E. Ash;David W. Christianson

  • Histone deacetylase 6 structure and molecular basis of catalysis and inhibition.

    Yang Hai;David W Christianson;David W Christianson

  • Catalysis By Metal-Activated Hydroxide in Zinc and Manganese Metalloenzymes

    Christianson Dw;Cox Jd

  • Bornyl diphosphate synthase: structure and strategy for carbocation manipulation by a terpenoid cyclase.

    Douglas A. Whittington;Mitchell L. Wise;Marek Urbansky;Robert M. Coates

  • Taxadiene synthase structure and evolution of modular architecture in terpene biosynthesis

    Mustafa Köksal;Yinghua Jin;Yinghua Jin;Robert M. Coates;Rodney Croteau

  • Crystal structure of the dimeric extracellular domain of human carbonic anhydrase XII, a bitopic membrane protein overexpressed in certain cancer tumor cells.

    Douglas A. Whittington;Abdul Waheed;Barbara Ulmasov;Gul N. Shah

  • Hydrogen bond stereochemistry in protein structure and function

    Joseph A. Ippolito;Richard S. Alexander;David W. Christianson

  • Unearthing the Roots of the Terpenome

    David W Christianson

  • Structure, mechanism, and inhibition of histone deacetylases and related metalloenzymes.

    Patrick M Lombardi;Kathryn E Cole;Daniel P Dowling;David W Christianson

  • Structure of trichodiene synthase from Fusarium sporotrichioides provides mechanistic inferences on the terpene cyclization cascade.

    Michael J. Rynkiewicz;David E. Cane;David W. Christianson

  • Arginase inhibition restores NOS coupling and reverses endothelial dysfunction and vascular stiffness in old rats.

    Jae Hyung Kim;Lukasz J. Bugaj;Young Jun Oh;Young Jun Oh;Trinity J. Bivalacqua

  • Detoxification of environmental mutagens and carcinogens: structure, mechanism, and evolution of liver epoxide hydrolase

    Maria A. Argiriadi;Christophe Morisseau;Bruce D. Hammock;David W. Christianson

  • Unexpected Ph-Dependent Conformation of His-64, the Proton Shuttle of Carbonic Anhydrase II.

    Satish K. Nair;David W. Christianson

  • Protein component of the ribozyme ribonuclease P alters substrate recognition by directly contacting precursor tRNA

    S. Niranjanakumari;Travis Stams;Sharon M. Crary;David W. Christianson

  • Structural chemistry and biology of manganese metalloenzymes

    David W. Christianson

  • Crystal structure of an uncleaved serpin reveals the conformation of an inhibitory reactive loop

    Anzhi Wei;Harvey Rubin;Barry S. Cooperman;David W. Christianson

Frequent Co-Authors

David E. Cane
David E. Cane Brown University
Carol A. Fierke
Carol A. Fierke Texas A&M University
Satish K. Nair
Satish K. Nair University of Illinois at Urbana-Champaign
William N. Lipscomb
William N. Lipscomb Harvard University
Christophe Morisseau
Christophe Morisseau University of California, Davis
Matthew A. Deardorff
Matthew A. Deardorff Children's Hospital of Philadelphia
Bruce D. Hammock
Bruce D. Hammock University of California, Davis
Harvey Rubin
Harvey Rubin University of Pennsylvania
Rudolf Konrad Allemann
Rudolf Konrad Allemann Cardiff University
Barry S. Cooperman
Barry S. Cooperman University of Pennsylvania

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