Alessio Innocenti

Overview

Best Publications

• Biochemical characterization of CA IX, one of the most active carbonic anhydrase isozymes.

  Mika Hilvo;Lina Baranauskiene;Anna Maria Salzano;Andrea Scaloni

  365
  Citations

• Carbonic anhydrase inhibitors. Inhibition of the transmembrane isozyme XII with sulfonamides-a new target for the design of antitumor and antiglaucoma drugs?

  Daniela Vullo;Alessio Innocenti;Isao Nishimori;Jaromı́r Pastorek

  265
  Citations

• Carbonic anhydrase inhibitors: inhibition of isozymes I, II, and IX with triazole-linked O-glycosides of benzene sulfonamides.

  Brendan Luke Wilkinson;Laurent Bornaghi;Todd Ashley Houston;Alessio Innocenti

  248
  Citations

• Polyamines inhibit carbonic anhydrases by anchoring to the zinc-coordinated water molecule

  Fabrizio Carta;Claudia Temperini;Alessio Innocenti;Andrea Scozzafava

  232
  Citations

• Carbonic anhydrase inhibitors. Inhibition of mammalian isoforms I-XIV with a series of natural product polyphenols and phenolic acids.

  Alessio Innocenti;S. Beyza Öztürk Sarıkaya;İlhami Gülçin;Claudiu T. Supuran

  231
  Citations

• Saccharin inhibits carbonic anhydrases: possible explanation for its unpleasant metallic aftertaste.

  Karen Köhler;Alexander Hillebrecht;Johannes Schulze Wischeler;Alessio Innocenti

  229
  Citations

• Carbonic anhydrase inhibitors: interactions of phenols with the 12 catalytically active mammalian isoforms (CA I-XIV).

  Alessio Innocenti;Daniela Vullo;Andrea Scozzafava;Claudiu T. Supuran

  217
  Citations

• A novel class of carbonic anhydrase inhibitors: glycoconjugate benzene sulfonamides prepared by "click-tailing".

  Brendan Luke Wilkinson;Laurent Bornaghi;Todd Ashley Houston;Alessio Innocenti

  207
  Citations

• Carbonic Anhydrase Inhibitors. The Mitochondrial Isozyme VB as a New Target for Sulfonamide and Sulfamate Inhibitors

  Isao Nishimori;Daniela Vullo;Alessio Innocenti;Andrea Scozzafava

  206
  Citations

• Carbonic anhydrase inhibitors: novel sulfonamides incorporating 1,3,5-triazine moieties as inhibitors of the cytosolic and tumour-associated carbonic anhydrase isozymes I, II and IX.

  Vladimir Garaj;Luca Puccetti;Giuseppe Fasolis;Jean-Yves Winum;Jean-Yves Winum

  192
  Citations

• Carbonic anhydrase inhibitors: clash with Ala65 as a means for designing inhibitors with low affinity for the ubiquitous isozyme II, exemplified by the crystal structure of the topiramate sulfamide analogue.

  ‡ Jean-Yves Winum;Claudia Temperini;Khaled El Cheikh;Alessio Innocenti

  190
  Citations

• Carbonic anhydrase inhibitors. Antioxidant polyphenols effectively inhibit mammalian isoforms I-XV.

  Alessio Innocenti;Ilhami Gülçin;Ilhami Gülçin;Andrea Scozzafava;Claudiu T. Supuran

  187
  Citations

• Root Effect Hemoglobin May Have Evolved to Enhance General Tissue Oxygen Delivery

  Jodie L. Rummer;Jodie L. Rummer;David J. McKenzie;Alessio Innocenti;Claudiu T. Supuran

  184
  Citations

• The coumarin-binding site in carbonic anhydrase accommodates structurally diverse inhibitors: the antiepileptic lacosamide as an example and lead molecule for novel classes of carbonic anhydrase inhibitors

  Claudia Temperini;Alessio Innocenti;Andrea Scozzafava;Seppo Parkkila

  177
  Citations

• Carbonic anhydrase inhibitors: inhibition of the transmembrane isozyme XIV with sulfonamides.

  Isao Nishimori;Daniela Vullo;Alessio Innocenti;Andrea Scozzafava

  176
  Citations

• Carbonic anhydrase inhibitors: inhibition of mammalian isoforms I-XIV with a series of substituted phenols including paracetamol and salicylic acid.

  Alessio Innocenti;Daniela Vullo;Andrea Scozzafava;Claudiu T. Supuran

  169
  Citations

• Carbonic anhydrase inhibitors. Inhibition of the human cytosolic isozyme VII with aromatic and heterocyclic sulfonamides.

  Daniela Vullo;Juha Voipio;Alessio Innocenti;Claudio Rivera

  168
  Citations

• Antiviral sulfonamide derivatives.

  Claudiu T. Supuran;Alessio Innocenti;Antonio Mastrolorenzo;Andrea Scozzafava

  164
  Citations

• Carbonic Anhydrase Inhibitors. Cloning, Characterization, and Inhibition Studies of a New β-Carbonic Anhydrase from Mycobacterium tuberculosis

  Isao Nishimori;Tomoko Minakuchi;Daniela Vullo;Andrea Scozzafava

  157
  Citations

• Sildenafil is a strong activator of mammalian carbonic anhydrase isoforms I-XIV.

  T. Abdülkadir Coban;Şükrü Beydemir;İlhami Gücin;Deniz Ekinci

  145
  Citations