Jaromir Pastorek

Research.com Recognitions

• Member of the European Academy of Sciences and Arts
• Member of the European Academy of Sciences and Arts
• Member of the European Academy of Sciences and Arts

Overview

Best Publications

• Hypoxia-inducible Expression of Tumor-associated Carbonic Anhydrases

  Charles C. Wykoff;Nigel J. P. Beasley;Peter H. Watson;Kevin J. Turner

  1564
  Citations

• Carbonic anhydrases: current state of the art, therapeutic applications and future prospects.

  Silvia Pastorekova;Seppo Parkkila;Jaromir Pastorek;Claudiu T Supuran

  966
  Citations

• Hypoxia activates the capacity of tumor-associated carbonic anhydrase IX to acidify extracellular pH.

  Eliška Švastová;Alžbeta Hulı́ková;Monika Rafajová;Miriam Zat'ovičová

  822
  Citations

• Carbonic anhydrase (CA IX) expression, a potential new intrinsic marker of hypoxia: correlations with tumor oxygen measurements and prognosis in locally advanced carcinoma of the cervix.

  Juliette A. Loncaster;Adrian L. Harris;Susan E. Davidson;John P. Logue

  717
  Citations

• Cloning and characterization of MN, a human tumor-associated protein with a domain homologous to carbonic anhydrase and a putative helix - Loop - helix DNA binding segment

  J. Pastorek;S. Pastorekova;I. Callebaut;Jp. Mornon

  649
  Citations

• Crystal structure of the catalytic domain of the tumor-associated human carbonic anhydrase IX

  Vincenzo Alterio;Mika Hilvo;Anna Di Fiore;Claudiu T. Supuran

  577
  Citations

• Prognostic Significance of a Novel Hypoxia-Regulated Marker, Carbonic Anhydrase IX, in Invasive Breast Carcinoma

  Stephen K. Chia;Charles C. Wykoff;Peter H. Watson;Cheng Han

  532
  Citations

• Human MN/CA9 gene, a novel member of the carbonic anhydrase family: Structure and exon to protein domain relationships

  René Opavský;Silvia Pastoreková;Vladimír Zelník;Adriana Gibadulinová

  484
  Citations

• Expression of Hypoxia-inducible Carbonic Anhydrase-9 Relates to Angiogenic Pathways and Independently to Poor Outcome in Non-Small Cell Lung Cancer

  Alexandra Giatromanolaki;Michael I. Koukourakis;Efthimios Sivridis;Jaromir Pastorek

  432
  Citations

• Carbonic anhydrase IX, MN/CA IX : Analysis of stomach complementary DNA sequence and expression in human and rat alimentary tracts

  S Pastorekova;S Parkkila;AK Parkkila;R Opavsky

  408
  Citations

• Carbonic anhydrase IX in oligodendroglial brain tumors

  Sally Järvelä;Seppo Parkkila;Helena Bragge;Marketta Kähkönen

  398
  Citations

• Biochemical characterization of CA IX, one of the most active carbonic anhydrase isozymes.

  Mika Hilvo;Lina Baranauskiene;Anna Maria Salzano;Andrea Scaloni

  365
  Citations

• Carbonic Anhydrase IX Expression, a Novel Surrogate Marker of Tumor Hypoxia, Is Associated With a Poor Prognosis in Non–Small-Cell Lung Cancer

  Daniel E.B. Swinson;J. Louise Jones;Donna Richardson;Charles C. Wykoff

  363
  Citations

• Hypoxia-induced carbonic anhydrase IX as a target for cancer therapy: from biology to clinical use.

  Jaromir Pastorek;Silvia Pastorekova

  355
  Citations

• Carbonic anhydrase inhibitor suppresses invasion of renal cancer cells in vitro.

  Seppo Parkkila;Hannu Rajaniemi;Anna-Kaisa Parkkila;Jyrki Kivelä

  346
  Citations

• Carbonic anhydrase IX reduces E-cadherin-mediated adhesion of MDCK cells via interaction with β-catenin

  Eliška Švastová;Norbert Žilka;Miriam Zat'ovičová;Adriana Gibadulinová

  329
  Citations

• Carbonic anhydrase IX, an endogenous hypoxia marker, expression in head and neck squamous cell carcinoma and its relationship to hypoxia, necrosis, and microvessel density.

  Nigel J. P. Beasley;Charles C. Wykoff;Peter H. Watson;Russell Leek

  322
  Citations

• Carbonic Anhydrase Inhibitors. Design of Fluorescent Sulfonamides as Probes of Tumor-Associated Carbonic Anhydrase IX That Inhibit Isozyme IX-Mediated Acidification of Hypoxic Tumors†

  Alessandro Cecchi;Alzbeta Hulikova;Jaromír Pastorek;Silvia Pastoreková

  317
  Citations

• Immunohistochemical study of colorectal tumors for expression of a novel transmembrane carbonic anhydrase, MN/CA IX, with potential value as a marker of cell proliferation

  Juha Saarnio;Seppo Parkkila;Anna-Kaisa Parkkila;Kari Haukipuro

  315
  Citations

• Expression of MaTu-MN protein in human tumor cultures and in clinical specimens.

  J. Závada;Z. Závadová;S. Pastoreková;F. Čiampor

  313
  Citations