Silvia Pastorekova

Overview

Best Publications

• Carbonic anhydrases: current state of the art, therapeutic applications and future prospects.

  Silvia Pastorekova;Seppo Parkkila;Jaromir Pastorek;Claudiu T Supuran

  966
  Citations

• Hypoxia activates the capacity of tumor-associated carbonic anhydrase IX to acidify extracellular pH.

  Eliška Švastová;Alžbeta Hulı́ková;Monika Rafajová;Miriam Zat'ovičová

  822
  Citations

• Cloning and characterization of MN, a human tumor-associated protein with a domain homologous to carbonic anhydrase and a putative helix - Loop - helix DNA binding segment

  J. Pastorek;S. Pastorekova;I. Callebaut;Jp. Mornon

  649
  Citations

• Crystal structure of the catalytic domain of the tumor-associated human carbonic anhydrase IX

  Vincenzo Alterio;Mika Hilvo;Anna Di Fiore;Claudiu T. Supuran

  577
  Citations

• Human MN/CA9 gene, a novel member of the carbonic anhydrase family: Structure and exon to protein domain relationships

  René Opavský;Silvia Pastoreková;Vladimír Zelník;Adriana Gibadulinová

  484
  Citations

• A novel quasi-viral agent, MaTu, is a two-component system

  Silvia Pastoreková;Zuzana Závadová;Michael Košťál;Olga Babušíková

  417
  Citations

• Carbonic anhydrase IX, MN/CA IX : Analysis of stomach complementary DNA sequence and expression in human and rat alimentary tracts

  S Pastorekova;S Parkkila;AK Parkkila;R Opavsky

  408
  Citations

• Carbonic anhydrase IX in oligodendroglial brain tumors

  Sally Järvelä;Seppo Parkkila;Helena Bragge;Marketta Kähkönen

  398
  Citations

• Biochemical characterization of CA IX, one of the most active carbonic anhydrase isozymes.

  Mika Hilvo;Lina Baranauskiene;Anna Maria Salzano;Andrea Scaloni

  365
  Citations

• Hypoxia-induced carbonic anhydrase IX as a target for cancer therapy: from biology to clinical use.

  Jaromir Pastorek;Silvia Pastorekova

  355
  Citations

• Carbonic anhydrase inhibitor suppresses invasion of renal cancer cells in vitro.

  Seppo Parkkila;Hannu Rajaniemi;Anna-Kaisa Parkkila;Jyrki Kivelä

  346
  Citations

• Carbonic anhydrase IX reduces E-cadherin-mediated adhesion of MDCK cells via interaction with β-catenin

  Eliška Švastová;Norbert Žilka;Miriam Zat'ovičová;Adriana Gibadulinová

  329
  Citations

• The role of carbonic anhydrase IX in cancer development: links to hypoxia, acidosis, and beyond

  Silvia Pastorekova;Robert J Gillies

  320
  Citations

• Carbonic Anhydrase Inhibitors. Design of Fluorescent Sulfonamides as Probes of Tumor-Associated Carbonic Anhydrase IX That Inhibit Isozyme IX-Mediated Acidification of Hypoxic Tumors†

  Alessandro Cecchi;Alzbeta Hulikova;Jaromír Pastorek;Silvia Pastoreková

  317
  Citations

• Immunohistochemical study of colorectal tumors for expression of a novel transmembrane carbonic anhydrase, MN/CA IX, with potential value as a marker of cell proliferation

  Juha Saarnio;Seppo Parkkila;Anna-Kaisa Parkkila;Kari Haukipuro

  315
  Citations

• Expression of MaTu-MN protein in human tumor cultures and in clinical specimens.

  J. Závada;Z. Závadová;S. Pastoreková;F. Čiampor

  313
  Citations

• Identification of the MN antigen as a diagnostic biomarker of cervical intraepithelial squamous and glandular neoplasia and cervical carcinomas.

  S Y Liao;C Brewer;J Závada;J Pastorek

  298
  Citations

• Carbonic anhydrase inhibitors. Inhibition of the transmembrane isozyme XII with sulfonamides-a new target for the design of antitumor and antiglaucoma drugs?

  Daniela Vullo;Alessio Innocenti;Isao Nishimori;Jaromı́r Pastorek

  265
  Citations

• Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozyme IX with aromatic and heterocyclic sulfonamides.

  Daniela Vullo;Marco Franchi;Enzo Gallori;Jaromir Pastorek

  253
  Citations

• Cancer-Associated Carbonic Anhydrases and Their Inhibition

  S Pastorekova;M Zatovicova;J Pastorek

  237
  Citations