William S. Sly

Research.com Recognitions

• 1994 - Fellow of the American Association for the Advancement of Science (AAAS)
• 1989 - Member of the National Academy of Sciences

Overview

Best Publications

• Human Carbonic Anhydrases and Carbonic Anhydrase Deficiencies

  William S. Sly;Peiyi Y. Hu

  1176
  Citations

• Carbonic anhydrase II deficiency identified as the primary defect in the autosomal recessive syndrome of osteopetrosis with renal tubular acidosis and cerebral calcification

  William S. Sly;David Hewett-Emmett;Michael P. Whyte;Ya-Shiou L. Yu

  851
  Citations

• Expression of Hypoxia-Inducible Cell-Surface Transmembrane Carbonic Anhydrases in Human Cancer

  Sergey Ivanov;Shu-Yuan Liao;Alla Ivanova;Alla Danilkovitch-Miagkova

  833
  Citations

• Phosphohexosyl components of a lysosomal enzyme are recognized by pinocytosis receptors on human fibroblasts

  Arnold Kaplan;Daniel T. Achord;William S. Sly

  766
  Citations

• Beta glucuronidase deficiency: report of clinical, radiologic, and biochemical features of a new mucopolysaccharidosis.

  William S. Sly;Barbara A. Quinton;William H. McAlister;David L. Rimoin

  650
  Citations

• The Hemochromatosis Founder Mutation in HLA-H Disrupts β2-Microglobulin Interaction and Cell Surface Expression

  John N. Feder;Zenta Tsuchihashi;Alivelu Irrinki;Vincent K. Lee

  626
  Citations

• HFE gene knockout produces mouse model of hereditary hemochromatosis

  Xiao Yan Zhou;Shunji Tomatsu;Robert E. Fleming;Seppo Parkkila

  615
  Citations

• Hereditary hemochromatosis: Effects of C282Y and H63D mutations on association with β2-microglobulin, intracellular processing, and cell surface expression of the HFE protein in COS-7 cells

  Abdul Waheed;Seppo Parkkila;Xiao Yan Zhou;Shunji Tomatsu

  536
  Citations

• Human carbonic anhydrase XII: cDNA cloning, expression, and chromosomal localization of a carbonic anhydrase gene that is overexpressed in some renal cell cancers

  Özlem Türeci;Ugur Sahin;Evi Vollmar;Stefan Siemer

  453
  Citations

• Insulin-like Growth Factor Receptor Expression and Function in Human Breast Cancer

  Kevin J. Cullen;Douglas Yee;William S. Sly;James Perdue

  436
  Citations

• Association of the transferrin receptor in human placenta with HFE, the protein defective in hereditary hemochromatosis

  Seppo Parkkila;Abdul Waheed;Robert S. Britton;Bruce R. Bacon

  409
  Citations

• Carbonic Anhydrase II Deficiency in 12 Families with the Autosomal Recessive Syndrome of Osteopetrosis with Renal Tubular Acidosis and Cerebral Calcification

  Sly Ws;Whyte Mp;Sundaram;Tashian Re

  404
  Citations

• Hepcidin: a putative iron-regulatory hormone relevant to hereditary hemochromatosis and the anemia of chronic disease.

  Robert E. Fleming;William S. Sly

  382
  Citations

• Transferrin receptor 2: Continued expression in mouse liver in the face of iron overload and in hereditary hemochromatosis

  Robert E. Fleming;Mary C. Migas;Christopher C. Holden;Abdul Waheed

  347
  Citations

• Carbonic anhydrase inhibitor suppresses invasion of renal cancer cells in vitro.

  Seppo Parkkila;Hannu Rajaniemi;Anna-Kaisa Parkkila;Jyrki Kivelä

  346
  Citations

• Decreased liver hepcidin expression in the Hfe knockout mouse.

  Kaashif A. Ahmad;John R. Ahmann;Mary C. Migas;Abdul Waheed

  345
  Citations

• The human cation-independent mannose 6-phosphate receptor. Cloning and sequence of the full-length cDNA and expression of functional receptor in COS cells.

  A Oshima;C M Nolan;J W Kyle;J H Grubb

  341
  Citations

• Mechanism of increased iron absorption in murine model of hereditary hemochromatosis: Increased duodenal expression of the iron transporter DMT1

  Robert E. Fleming;Mary C. Migas;Xiao Yan Zhou;Jinxing Jiang

  316
  Citations

• Hereditary hemochromatosis: Effects of C282Y and H63D mutations on association with b2-microglobulin, intracellular processing, and cell surface expression of the HFE protein in COS-7 cells (degradationyGolgi processingyintracellular transportyironymajor histocompatibility complex class I protein)

  Abdul Waheed;Seppo Parkkila;Xiao Yan Zhou;Shunji Tomatsu

  4
  Citations

• HFE gene knockout produces mouse model of hereditary hemochromatosis (major histocompatibility complex class I proteinyironyliverygene targeting)

  Xiao Yan Zhou;Shunji Tomatsu;Robert E. Fleming;S Eppo Parkkila

  1
  Citations