What is he best known for?
The fields of study he is best known for:
- Gene
- Internal medicine
- Enzyme
The scientist’s investigation covers issues in Biochemistry, Molecular biology, Mucopolysaccharidosis, Genetics and Mucopolysaccharidosis Type IVA.
The various areas that Tadao Orii examines in his Molecular biology study include Gene expression, Thiolase, 3-Hydroxyacyl-CoA Dehydrogenase, Gene mutation and Complementary DNA.
His Complementary DNA research includes elements of Peroxisomal disorder, Open reading frame and Mutant.
His research in Mucopolysaccharidosis intersects with topics in Immunology, Bone marrow, Sulfatase and Enzyme replacement therapy.
His research integrates issues of Endocrinology, Urinary system and Surgery, Family history in his study of Enzyme replacement therapy.
He interconnects Lysosomal storage disease, Natural history, Allele, Genetic heterogeneity and Elosulfase alfa in the investigation of issues within Mucopolysaccharidosis Type IVA.
His most cited work include:
- A human gene responsible for Zellweger syndrome that affects peroxisome assembly. (314 citations)
- Novel fatty acid beta-oxidation enzymes in rat liver mitochondria. II. Purification and properties of enoyl-coenzyme A (CoA) hydratase/3-hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase trifunctional protein. (291 citations)
- International Morquio A Registry: Clinical manifestation and natural course of Morquio A disease (236 citations)
What are the main themes of his work throughout his whole career to date?
Molecular biology, Internal medicine, Biochemistry, Genetics and Endocrinology are his primary areas of study.
The concepts of his Molecular biology study are interwoven with issues in Thiolase, Mutation, Point mutation, Mucopolysaccharidosis and Complementary DNA.
His Mucopolysaccharidosis study incorporates themes from Keratan sulfate and Sulfatase, Mucopolysaccharidosis Type IVA, Enzyme replacement therapy.
Tadao Orii has researched Internal medicine in several fields, including Gastroenterology and Immunology.
His work on Biochemistry deals in particular with Peroxisome, Enzyme, Zellweger syndrome, Mitochondrion and Glycoprotein.
His is involved in several facets of Genetics study, as is seen by his studies on Gene, Exon, Missense mutation, Allele and Restriction fragment length polymorphism.
He most often published in these fields:
- Molecular biology (26.82%)
- Internal medicine (23.06%)
- Biochemistry (22.31%)
What were the highlights of his more recent work (between 2012-2020)?
- Mucopolysaccharidosis (14.54%)
- Enzyme replacement therapy (8.02%)
- Keratan sulfate (6.02%)
In recent papers he was focusing on the following fields of study:
Tadao Orii mainly focuses on Mucopolysaccharidosis, Enzyme replacement therapy, Keratan sulfate, Internal medicine and Hematopoietic stem cell transplantation.
His Mucopolysaccharidosis research includes themes of Mucopolysaccharidosis Type IVA and Bone marrow.
His work deals with themes such as Stage, Surgery, Newborn screening and Dysplasia, which intersect with Enzyme replacement therapy.
His Keratan sulfate research is multidisciplinary, incorporating elements of Heparan sulfate, Dermatan sulfate, Immunology, Urine and Biomarker.
Tadao Orii combines subjects such as Gastroenterology and Physical therapy with his study of Internal medicine.
His biological study spans a wide range of topics, including Molecular biology, Endocrinology and Lysosomal storage disorders.
Between 2012 and 2020, his most popular works were:
- Review of clinical presentation and diagnosis of mucopolysaccharidosis IVA (107 citations)
- Newborn screening and diagnosis of mucopolysaccharidoses (97 citations)
- Epidemiology of mucopolysaccharidoses (86 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Internal medicine
- Enzyme
His scientific interests lie mostly in Mucopolysaccharidosis, Enzyme replacement therapy, Surgery, Dysplasia and Internal medicine.
He has included themes like Immunology, Bone marrow, Mucopolysaccharidosis Type IVA and Cartilage in his Mucopolysaccharidosis study.
His Immunology research focuses on subjects like Keratan sulfate, which are linked to Phenotype, Genotype, Sulfatase, Missense mutation and Allelic heterogeneity.
His Enzyme replacement therapy study integrates concerns from other disciplines, such as Stage, Hematopoietic stem cell transplantation, Bone disease and Newborn screening.
In his study, Transplantation is strongly linked to Urinary system, which falls under the umbrella field of Dysplasia.
His Internal medicine research is multidisciplinary, relying on both Gastroenterology and Endocrinology.
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