D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 61 Citations 12,214 159 World Ranking 7479 National Ranking 528

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • DNA

Takashi Osumi focuses on Biochemistry, Peroxisome, Molecular biology, Enzyme and Peptide sequence. His Biochemistry study frequently intersects with other fields, such as Cell biology. His biological study spans a wide range of topics, including Enzyme inducer and Peroxisome proliferator-activated receptor alpha.

He has researched Molecular biology in several fields, including Thiolase, Complementary DNA, Peroxisome proliferator-activated receptor, Gene and Oxidase test. His Dehydrogenase, Enzyme assay and Rat liver study in the realm of Enzyme connects with subjects such as Phthalate. His study in Peptide sequence is interdisciplinary in nature, drawing from both Membrane transport and Transmembrane protein.

His most cited work include:

  • The 70-kDa peroxisomal membrane protein is a member of the Mdr (P-glycoprotein)-related ATP-binding protein superfamily. (337 citations)
  • FSP27 contributes to efficient energy storage in murine white adipocytes by promoting the formation of unilocular lipid droplets (314 citations)
  • Transcription regulation of peroxisomal fatty acyl-CoA oxidase and enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase in rat liver by peroxisome proliferators (288 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of investigation include Biochemistry, Molecular biology, Peroxisome, Cell biology and Complementary DNA. Enzyme, Thiolase, Peptide sequence, Peroxisomal targeting signal and Amino acid are among the areas of Biochemistry where the researcher is concentrating his efforts. His Molecular biology study combines topics in areas such as Mutation, Nucleic acid sequence, Gene, cDNA library and Promoter.

Takashi Osumi has included themes like Complementation, Mutant and Chinese hamster ovary cell in his Peroxisome study. The Cell biology study which covers Perilipin that intersects with Transcriptional regulation. His Complementary DNA study incorporates themes from Protein primary structure, Messenger RNA and Coding region.

He most often published in these fields:

  • Biochemistry (54.32%)
  • Molecular biology (38.89%)
  • Peroxisome (37.65%)

What were the highlights of his more recent work (between 2006-2016)?

  • Cell biology (19.75%)
  • Lipid droplet (8.02%)
  • Biochemistry (54.32%)

In recent papers he was focusing on the following fields of study:

His primary scientific interests are in Cell biology, Lipid droplet, Biochemistry, Perilipin and Molecular biology. The various areas that Takashi Osumi examines in his Cell biology study include Human Induced Pluripotent Stem Cells and Nuclear lamina. His Lipid droplet research is multidisciplinary, relying on both Lipid metabolism, Endocrinology, Diacylglycerol kinase and Adipose triglyceride lipase.

His study in Biochemistry focuses on Fatty acid, Beta oxidation and Cytoplasm. His Fatty acid study integrates concerns from other disciplines, such as Peroxisome, Hormone and Lipid Droplet Associated Proteins. His research integrates issues of Regulation of gene expression, Transcription factor, Gene, Mutant and Promoter in his study of Molecular biology.

Between 2006 and 2016, his most popular works were:

  • FSP27 contributes to efficient energy storage in murine white adipocytes by promoting the formation of unilocular lipid droplets (314 citations)
  • Perilipin 5, a Lipid Droplet-binding Protein, Protects Heart from Oxidative Burden by Sequestering Fatty Acid from Excessive Oxidation (140 citations)
  • CGI-58 facilitates lipolysis on lipid droplets but is not involved in the vesiculation of lipid droplets caused by hormonal stimulation. (134 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

His scientific interests lie mostly in Lipid droplet, Perilipin, Biochemistry, Adipose triglyceride lipase and Lipid metabolism. His work focuses on many connections between Lipid droplet and other disciplines, such as Endocrinology, that overlap with his field of interest in Congenital ichthyosiform erythroderma and Congenital ichthyosis. His research in Biochemistry is mostly concerned with Cytoplasm.

His Adipose triglyceride lipase research incorporates elements of Hormone-sensitive lipase and Activator. Takashi Osumi combines subjects such as Oxidative stress, Beta oxidation, Fatty acid and Reactive oxygen species with his study of Lipid metabolism. His studies in Cell biology integrate themes in fields like Coactivator, Ichthyosis, COS cells and Protein family.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

The 70-kDa peroxisomal membrane protein is a member of the Mdr (P-glycoprotein)-related ATP-binding protein superfamily.

K Kamijo;S Taketani;S Yokota;T Osumi.
Journal of Biological Chemistry (1990)

518 Citations

Transcription regulation of peroxisomal fatty acyl-CoA oxidase and enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase in rat liver by peroxisome proliferators

J K Reddy;S K Goel;M R Nemali;J J Carrino.
Proceedings of the National Academy of Sciences of the United States of America (1986)

435 Citations

FSP27 contributes to efficient energy storage in murine white adipocytes by promoting the formation of unilocular lipid droplets

Naonobu Nishino;Yoshikazu Tamori;Sanshiro Tateya;Takayuki Kawaguchi.
Journal of Clinical Investigation (2008)

417 Citations

Amino-terminal presequence of the precursor of peroxisomal 3-ketoacyl-CoA thiolase is a cleavable signal peptide for peroxisomal targeting

Takashi Osumi;Toshiro Tsukamoto;Shingo Hata;Sadaki Yokota.
Biochemical and Biophysical Research Communications (1991)

382 Citations

CGI-58 Interacts with Perilipin and Is Localized to Lipid Droplets POSSIBLE INVOLVEMENT OF CGI-58 MISLOCALIZATION IN CHANARIN-DORFMAN SYNDROME

Tomohiro Yamaguchi;Naoto Omatsu;Shuhei Matsushita;Takashi Osumi.
Journal of Biological Chemistry (2004)

317 Citations

Purification and properties of acyl-CoA oxidase from rat liver.

Takashi Osumi;Takashi Hashimoto;Nobuo Ui.
Journal of Biochemistry (1980)

315 Citations

Two cis-acting regulatory sequences in the peroxisome proliferator-responsive enhancer region of rat acyl-CoA oxidase gene.

Takashi Osumi;Jin-Kun Wen;Takashi Hashimoto.
Biochemical and Biophysical Research Communications (1991)

287 Citations

Complete nucleotide sequence of cDNA and predicted amino acid sequence of rat acyl-CoA oxidase.

S Miyazawa;H Hayashi;M Hijikata;N Ishii.
Journal of Biological Chemistry (1987)

280 Citations

Acyl-CoA oxidase of rat liver: a new enzyme for fatty acid oxidation.

Takashi Osumi;Takashi Hashimoto.
Biochemical and Biophysical Research Communications (1978)

275 Citations

Peroxisome Targeting Signal Type 1 (PTS1) Receptor Is Involved in Import of Both PTS1 and PTS2: Studies with PEX5-Defective CHO Cell Mutants

Hidenori Otera;Kanji Okumoto;Keita Tateishi;Yuka Ikoma.
Molecular and Cellular Biology (1998)

272 Citations

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