World's Best Scientists 2026 revealed!
Takashi Hashimoto

Takashi Hashimoto

Overview

Takashi Hashimoto was affiliated with Shinshu University in Japan. Their research spanned multiple disciplines with a primary focus on biochemistry, genetics, and molecular biology. Additional domains of study included medicine and agricultural and biological sciences, reflecting a multidisciplinary approach.

Their scientific contributions centered largely on plant science, molecular biology, genetics, cell biology, and pathology and forensic medicine. These subfields complemented a range of investigative topics that Hashimoto addressed throughout their career.

  • Plant Molecular Biology Research
  • Microtubule and mitosis dynamics
  • Photosynthetic Processes and Mechanisms
  • Plant nutrient uptake and metabolism
  • Autoimmune Bullous Skin Diseases
  • Plant Reproductive Biology
  • Plant Parasitism and Resistance

Hashimoto coauthored multiple publications with frequent collaborators including Tsubasa Shoji, Chiharu Tateishi, Masayoshi Nakamura, Shinichiro Komaki, and Kazuki Saito. These collaborations underline a sustained network of scientific partnerships in related research areas.

Their work was published across several scientific venues, particularly:

  • Nature Communications
  • Histochemistry and Cell Biology
  • Symmetry
  • Plant and Cell Physiology
  • PLANT PHYSIOLOGY

Recent published papers featuring Hashimoto's involvement include:

  • "Genetic Manipulation of Transcriptional Regulators Alters Nicotine Biosynthesis in Tobacco" (2020) in Plant and Cell Physiology
  • "Functional Analysis of the Plant Chromosomal Passenger Complex" (2020) in PLANT PHYSIOLOGY
  • "Mechanistic Insights into Plant Chiral Growth" (2020) in Symmetry
  • "CRISPR/Cas9-mediated disruption of the PYRROLIDINE KETIDE SYNTHASE gene reduces the accumulation of tropane alkaloids in Atropa belladonna hairy roots" (2021) in Bioscience Biotechnology and Biochemistry
  • "The association between MRI findings and breast cancer subtypes: focused on the combination patterns on diffusion-weighted and T2-weighted images" (2020) in Breast Cancer

The scope of Hashimoto's research incorporated genetic manipulation, plant biochemical pathways, cellular and molecular mechanisms in plant development, and applications of CRISPR technology. The diversity of venues and topics also indicates engagement with medical imaging and pathology, highlighting an interdisciplinary research trajectory.

Best Publications

  • PEROXISOMAL β-OXIDATION AND PEROXISOME PROLIFERATOR–ACTIVATED RECEPTOR α: An Adaptive Metabolic System

    Janardan K. Reddy;Takashi Hashimoto

  • Altered Constitutive Expression of Fatty Acid-metabolizing Enzymes in Mice Lacking the Peroxisome Proliferator-activated Receptor α (PPARα)

    Toshifumi Aoyama;Jeffrey M. Peters;Nobuko Iritani;Tamie Nakajima

  • The 70-kDa peroxisomal membrane protein is a member of the Mdr (P-glycoprotein)-related ATP-binding protein superfamily.

    K Kamijo;S Taketani;S Yokota;T Osumi

  • Defect in Peroxisome Proliferator-activated Receptor α-inducible Fatty Acid Oxidation Determines the Severity of Hepatic Steatosis in Response to Fasting *

    Takashi Hashimoto;William S. Cook;Chao Qi;Anjana V. Yeldandi

  • Novel fatty acid beta-oxidation enzymes in rat liver mitochondria. II. Purification and properties of enoyl-coenzyme A (CoA) hydratase/3-hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase trifunctional protein.

    Y Uchida;K Izai;T Orii;T Hashimoto

  • Transcription regulation of peroxisomal fatty acyl-CoA oxidase and enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase in rat liver by peroxisome proliferators

    J K Reddy;S K Goel;M R Nemali;J J Carrino

  • Amino-terminal presequence of the precursor of peroxisomal 3-ketoacyl-CoA thiolase is a cleavable signal peptide for peroxisomal targeting

    Takashi Osumi;Toshiro Tsukamoto;Shingo Hata;Sadaki Yokota

  • Novel fatty acid beta-oxidation enzymes in rat liver mitochondria. I. Purification and properties of very-long-chain acyl-coenzyme A dehydrogenase.

    K Izai;Y Uchida;T Orii;S Yamamoto

  • Purification and properties of acyl-CoA oxidase from rat liver.

    Takashi Osumi;Takashi Hashimoto;Nobuo Ui

  • Peroxisomal and mitochondrial fatty acid beta-oxidation in mice nullizygous for both peroxisome proliferator-activated receptor alpha and peroxisomal fatty acyl-CoA oxidase. Genotype correlation with fatty liver phenotype.

    Takashi Hashimoto;Tomoyuki Fujita;Nobuteru Usuda;William Cook

  • Tea Catechin Suppresses Adipocyte Differentiation Accompanied by Down-regulation of PPARγ2 and C/EBPα in 3T3-L1 Cells

    Takashi Furuyashiki;Hironobu Nagayasu;Yukiko Aoki;Hiroaki Bessho

  • Acyl-CoA oxidase of rat liver: a new enzyme for fatty acid oxidation.

    Takashi Osumi;Takashi Hashimoto

  • Two cis-acting regulatory sequences in the peroxisome proliferator-responsive enhancer region of rat acyl-CoA oxidase gene.

    Takashi Osumi;Jin-Kun Wen;Takashi Hashimoto

  • Complete nucleotide sequence of cDNA and predicted amino acid sequence of rat acyl-CoA oxidase.

    S Miyazawa;H Hayashi;M Hijikata;N Ishii

  • Enhancement of Fatty Acyl-CoA Oxidizing Activity in Rat Liver Peroxisomes by Di-(2-Ethylhexyl)Phthalate

    Takashi Osumi;Takashi Hashimoto

  • The presence of a new 3-oxoacyl-CoA thiolase in rat liver peroxisomes.

    Shoko Miyazawa;Takashi Osumi;Takashi Hashimoto

  • Peroxisome targeting signal of rat liver acyl-coenzyme A oxidase resides at the carboxy terminus.

    S Miyazawa;T Osumi;T Hashimoto;K Ohno

  • Peroxisomal βoxidation system of rat liver. Copurification of enoyl-CoA hydratase and 3-hydroxyacyl-CoA dehydrogenase

    Takashi Osumi;Takashi Hashimoto

  • Human peroxisomal 3-oxoacyl-coenzyme A thiolase deficiency

    A W Schram;S Goldfischer;C W van Roermund;E M Brouwer-Kelder

  • Comparison of Constitutive and Inducible Levels of Expression of Peroxisomal β-Oxidation and Catalase Genes in Liver and Extrahepatic Tissues of Rat

    Nemali Mr;Usuda N;Reddy Mk;Oyasu K

Frequent Co-Authors

Takashi Osumi
Takashi Osumi University of Hyogo
Seiji Yamaguchi
Seiji Yamaguchi Shimane University
Toshifumi Aoyama
Toshifumi Aoyama Shinshu University
Toshiyuki Fukao
Toshiyuki Fukao Gifu University
Yasuyuki Suzuki
Yasuyuki Suzuki Gifu University
Nobuyuki Shimozawa
Nobuyuki Shimozawa Gifu University
Naomi Kondo
Naomi Kondo Gifu University
J. M. Tager
J. M. Tager University of Amsterdam
H. van den Bosch
H. van den Bosch Utrecht University
Masaki Takiguchi
Masaki Takiguchi Chiba University

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Best Scientists Citing Takashi Hashimoto