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Masaki Takiguchi

Masaki Takiguchi

D-Index & Metrics

Biology and Biochemistry

D-Index
53
Citations
8120
World Ranking
16347
National Ranking
1173

Overview

Masaki Takiguchi is affiliated with Chiba University in Japan and conducts research primarily in the fields of Medicine and Neuroscience, with a particular focus on Neurology and Physiology. Their work addresses topics related to Parkinson's Disease mechanisms and treatments, Alzheimer's disease research and treatments, as well as neuroinflammation and neurodegeneration mechanisms.

Takiguchi's recent research includes the publication titled "A53T mutant α-synuclein fibrils formed in macrophage are spread to neurons" from 2022, which appeared in the journal Cellular and Molecular Life Sciences.

Frequent coauthors collaborating with Takiguchi include:

  • Shogo Moriya
  • Michiko Hanazono
  • Takeshi Fukuhara
  • Katsuro Iwase
  • Nobutaka Hattori

Publications by Takiguchi have appeared mainly in the venue Cellular and Molecular Life Sciences.

The main topics addressed in Takiguchi's research are:

  • Parkinson's Disease Mechanisms and Treatments
  • Alzheimer's disease research and treatments
  • Neuroinflammation and Neurodegeneration Mechanisms

Takiguchi's research contributions have focused on understanding the pathological processes underlying neurodegenerative diseases, particularly how mutant α-synuclein fibrils contribute to neuron-to-neuron transmission and the role of immune cells such as macrophages in this process.

Best Publications

  • Nitric oxide-induced apoptosis in pancreatic β cells is mediated by the endoplasmic reticulum stress pathway

    Seiichi Oyadomari;Kiyoshi Takeda;Masaki Takiguchi;Tomomi Gotoh

  • ENDODERM-SPECIFIC GENE EXPRESSION IN EMBRYONIC STEM CELLS DIFFERENTIATED TO EMBRYOID BODIES

    Koichiro Abe;Hitoshi Niwa;Katsuro Iwase;Masaki Takiguchi

  • Molecular cloning of cDNA for nonhepatic mitochondrial arginase (arginase II) and comparison of its induction with nitric oxide synthase in a murine macrophage-like cell line

    Tomomi Gotoh;Takashi Sonoki;Akitoshi Nagasaki;Kazutoyo Terada

  • Coinduction of Nitric-oxide Synthase and Arginase I in Cultured Rat Peritoneal Macrophages and Rat Tissues in Vivo by Lipopolysaccharide

    Takashi Sonoki;Akitoshi Nagasaki;Tomomi Gotoh;Masaki Takiguchi

  • Molecular classification and survival prediction in human gliomas based on proteome analysis.

    Yasuo Iwadate;Tsukasa Sakaida;Takaki Hiwasa;Yuichiro Nagai

  • Coinduction of Nitric Oxide Synthase, Argininosuccinate Synthetase, and Argininosuccinate Lyase in Lipopolysaccharide-treated Rats: RNA BLOT, IMMUNOBLOT, AND IMMUNOHISTOCHEMICAL ANALYSES

    Akitoshi Nagasaki;Tomomi Gotoh;Motohiro Takeya;Yingjie Yu

  • The C/EBP family of transcription factors in the liver and other organs

    Masaki Takiguchi

  • Molecular cloning and nucleotide sequence of cDNA for human liver arginase.

    Yougo Haraguchi;Masaki Takiguchi;Yoshihiro Amaya;Susumu Kawamoto

  • Chicken ovalbumin upstream promoter-transcription factor (COUP-TF) represses transcription from the promoter of the gene for ornithine transcarbamylase in a manner antagonistic to hepatocyte nuclear factor-4 (HNF-4).

    A Kimura;A Nishiyori;T Murakami;T Tsukamoto

  • Structure of the human ornithine transcarbamylase gene

    Akira Hata;Teruhisa Tsuzuki;Kazunori Shimada;Masaki Takiguchi

  • Biosynthesis and intracellular transport of enzymes of peroxisomal beta-oxidation.

    S Miura;M Mori;M Takiguchi;M Tatibana

  • Serological identification of TROP2 by recombinant cDNA expression cloning using sera of patients with esophageal squamous cell carcinoma

    Kazue Nakashima;Hideaki Shimada;Takenori Ochiai;Mari Kuboshima

  • Induction of Endothelial Nitric-oxide Synthase in Rat Brain Astrocytes by Systemic Lipopolysaccharide Treatment

    Katsuro Iwase;Kei Miyanaka;Atsuko Shimizu;Akitoshi Nagasaki

  • Functional association between CBP and HNF4 in trans-activation.

    Eisaku Yoshida;Satoko Aratani;Hiroshi Itou;Makoto Miyagishi

  • Cathepsin D Is a Potential Serum Marker for Poor Prognosis in Glioma Patients

    Mieko E. Fukuda;Yasuo Iwadate;Toshio Machida;Takaki Hiwasa

  • Transcriptional regulation of genes for ornithine cycle enzymes

    M Takiguchi;M Mori

  • The glucocorticoid-responsive gene cascade: Activation of the rat arginase gene through induction of C/EBPβ

    Tomomi Gotoh;Shoaib Chowdhury;Masaki Takiguchi;Masataka Mori

  • Gene expression profiling reveals the mechanism and pathophysiology of mouse liver regeneration

    Makoto Arai;Osamu Yokosuka;Tetsuhiro Chiba;Fumio Imazeki

  • Determination of tissue specificity of the enhancer by combinatorial operation of tissue-enriched transcription factors. Both HNF-4 and C/EBP beta are required for liver-specific activity of the ornithine transcarbamylase enhancer.

    Atsushi Nishiyori;Hidetoshi Tashiro;Akira Kimura;Kiwamu Akagi

  • Molecular cloning and nucleotide sequence of cDNA for rat ornithine carbamoyltransferase precursor.

    Masaki Takiguchi;Satoshi Miura;Masataka Mori;Masamiti Tatibana

Frequent Co-Authors

Masataka Mori
Masataka Mori Kumamoto University
Naohiko Seki
Naohiko Seki Chiba University
Tomomi Gotoh
Tomomi Gotoh Kumamoto University
Kohji Fukunaga
Kohji Fukunaga Tohoku University
Ichiro Matsuda
Ichiro Matsuda Kumamoto University
Takashi Hashimoto
Takashi Hashimoto Shinshu University
Shigenobu Shibata
Shigenobu Shibata Waseda University
Ken Ichi Yamamura
Ken Ichi Yamamura Kumamoto University
Osamu Yokosuka
Osamu Yokosuka Chiba University
Takehiko Fujisawa
Takehiko Fujisawa Chiba University

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