Tomomi Gotoh

Overview

Best Publications

• ER Stress Triggers Apoptosis by Activating BH3-Only Protein Bim

  Hamsa Puthalakath;Lorraine A. O'Reilly;Priscilla Gunn;Lily Lee

  1678
  Citations

• Targeted disruption of the Chop gene delays endoplasmic reticulum stress–mediated diabetes

  Seiichi Oyadomari;Akio Koizumi;Kiyoshi Takeda;Tomomi Gotoh

  1287
  Citations

• Ischemia-induced neuronal cell death is mediated by the endoplasmic reticulum stress pathway involving CHOP

  S. Tajiri;S. Oyadomari;S. Yano;M. Morioka

  571
  Citations

• hsp70-DnaJ chaperone pair prevents nitric oxide- and CHOP-induced apoptosis by inhibiting translocation of Bax to mitochondria

  Tomomi Gotoh;K. Terada;S. Oyadomari;M. Mori

  493
  Citations

• Arginase II Downregulates Nitric Oxide (NO) Production and Prevents NO-mediated Apoptosis in Murine Macrophage-derived RAW 264.7 Cells

  Tomomi Gotoh;Masataka Mori

  279
  Citations

• Coinduction of Nitric-oxide Synthase and Arginase I in Cultured Rat Peritoneal Macrophages and Rat Tissues in Vivo by Lipopolysaccharide

  Takashi Sonoki;Akitoshi Nagasaki;Tomomi Gotoh;Masaki Takiguchi

  261
  Citations

• C/EBP homologous protein (CHOP) is crucial for the induction of caspase-11 and the pathogenesis of lipopolysaccharide-induced inflammation.

  Motoyoshi Endo;Masataka Mori;Shizuo Akira;Tomomi Gotoh

  252
  Citations

• The Endoplasmic Reticulum Stress-C/EBP Homologous Protein Pathway-Mediated Apoptosis in Macrophages Contributes to the Instability of Atherosclerotic Plaques

  Hiroto Tsukano;Tomomi Gotoh;Motoyoshi Endo;Keishi Miyata

  228
  Citations

• Arginine Metabolic Enzymes, Nitric Oxide and Infection

  Masataka Mori;Tomomi Gotoh

  199
  Citations

• Mitochondrial Dysfunction and Increased Reactive Oxygen Species Impair Insulin Secretion in Sphingomyelin Synthase 1-null Mice

  Masato Yano;Ken Watanabe;Tadashi Yamamoto;Kazutaka Ikeda

  195
  Citations

• Coinduction of Nitric Oxide Synthase, Argininosuccinate Synthetase, and Argininosuccinate Lyase in Lipopolysaccharide-treated Rats: RNA BLOT, IMMUNOBLOT, AND IMMUNOHISTOCHEMICAL ANALYSES

  Akitoshi Nagasaki;Tomomi Gotoh;Motohiro Takeya;Yingjie Yu

  184
  Citations

• L-arginine uptake, the citrulline-NO cycle and arginase II in the rat brain: an in situ hybridization study.

  Olivier Braissant;Tomomi Gotoh;Marc Loup;Masataka Mori

  172
  Citations

• Distinct arginase isoforms expressed in primary and transformed macrophages: regulation by oxygen tension

  Claudine A. Louis;Jonathan S. Reichner;William L. Henry;Balduino Mastrofrancesco

  160
  Citations

• Regulation of the genes for arginase isoforms and related enzymes in mouse macrophages by lipopolysaccharide

  Salimuddin;Akitoshi Nagasaki;Tomomi Gotoh;Hirotaka Isobe

  151
  Citations

• Positive role of CCAAT/enhancer-binding protein homologous protein, a transcription factor involved in the endoplasmic reticulum stress response in the development of colitis

  Takushi Namba;Ken Ichiro Tanaka;Yosuke Ito;Tomoaki Ishihara

  130
  Citations

• The glucocorticoid-responsive gene cascade: Activation of the rat arginase gene through induction of C/EBPβ

  Tomomi Gotoh;Shoaib Chowdhury;Masaki Takiguchi;Masataka Mori

  124
  Citations

• CCAAT/Enhancer-Binding Protein Homologous Protein (CHOP) Regulates Osteoblast Differentiation

  Ken Shirakawa;Shingo Maeda;Tomomi Gotoh;Makoto Hayashi

  123
  Citations

• Chromosomal localization of the human arginase II gene and tissue distribution of its mRNA.

  Tomomi Gotoh;Masatake Araki;Masataka Mori

  121
  Citations

• Induction of the C/EBP beta gene by dexamethasone and glucagon in primary-cultured rat hepatocytes.

  Fumihiko Matsuno;Shoaib Chowdhury;Tomomi Gotoh;Katsuro Iwase

  96
  Citations

• Effects of arginase isoforms on NO Production by nNOS.

  Loretta G. Que;Samuel E. George;Tomomi Gotoh;Masataka Mori

  74
  Citations