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Shinichi Kohsaka

Shinichi Kohsaka

D-Index & Metrics

Neuroscience

D-Index
86
Citations
30131
World Ranking
1282
National Ranking
19

Overview

Shinichi Kohsaka is affiliated with Keio University in Japan and focuses on research within the fields of Neuroscience and Immunology and Microbiology. Their scholarly contributions span multiple subfields including Neurology, Immunology, Developmental Neuroscience, and Cellular and Molecular Neuroscience.

Their research topics encompass the following areas:

  • Neuroinflammation and Neurodegeneration Mechanisms
  • Neurogenesis and neuroplasticity mechanisms
  • Immune cells in cancer
  • Neuroscience and Neuropharmacology Research
  • Immune Response and Inflammation

Kohsaka has published in several venues, with contributions appearing in:

  • The Journal of Experimental Medicine
  • bioRxiv (Cold Spring Harbor Laboratory)
  • International Journal of Molecular Sciences

Recent papers include:

  • "Synaptic pruning of murine adult-born neurons by microglia depends on phosphatidylserine" (2022) published in The Journal of Experimental Medicine
  • "Hematopoietic growth factors Regulate Entry of Monocytes into the Adult Brain via Chemokine Receptor CCR5" (2024) published in bioRxiv (Cold Spring Harbor Laboratory)
  • "Hematopoietic Growth Factors Regulate the Entry of Monocytes into the Adult Brain via Chemokine Receptor CCR5" (2024) published in International Journal of Molecular Sciences

Frequent collaborators are:

  • Junchi He
  • Li-Ru Zhao
  • Chihiro Kurematsu
  • Masato Sawada
  • Masaki Ohmuraya

Best Publications

  • Resting Microglia Directly Monitor the Functional State of Synapses In Vivo and Determine the Fate of Ischemic Terminals

    Hiroaki Wake;Andrew J. Moorhouse;Andrew J. Moorhouse;Shozo Jinno;Shinichi Kohsaka

  • P2x4 receptors induced in spinal microglia gate tactile allodynia after nerve injury

    Makoto Tsuda;Yukari Shigemoto-Mogami;Schuichi Koizumi;Akito Mizokoshi

  • Microglia-specific localisation of a novel calcium binding protein, Iba1

    Daisuke Ito;Yoshinori Imai;Keiko Ohsawa;Kazuyuki Nakajima

  • UDP acting at P2Y6 receptors is a mediator of microglial phagocytosis

    Schuichi Koizumi;Yukari Shigemoto-Mogami;Kaoru Nasu-Tada;Yoichi Shinozaki

  • Extracellular ATP or ADP induce chemotaxis of cultured microglia through Gi/o-coupled P2Y receptors.

    Shizuyo Honda;Yo Sasaki;Keiko Ohsawa;Yoshinori Imai

  • Dynamics of the microglial/amyloid interaction indicate a role in plaque maintenance.

    Tristan Bolmont;Florent Haiss;Daniel Eicke;Rebecca Radde

  • Production and Release of Neuroprotective Tumor Necrosis Factor by P2X7 Receptor-Activated Microglia

    Tomohisa Suzuki;Izumi Hide;Katsutoshi Ido;Shinichi Kohsaka

  • The origin and cell lineage of microglia: new concepts.

    W.Y. Chan;S. Kohsaka;P. Rezaie;P. Rezaie

  • Extracellular ATP Triggers Tumor Necrosis Factor-α Release from Rat Microglia

    Izumi Hide;Masaya Tanaka;Atsuko Inoue;Kazuyuki Nakajima

  • Microglia–Müller Glia Cell Interactions Control Neurotrophic Factor Production during Light-Induced Retinal Degeneration

    Takayuki Harada;Chikako Harada;Shinichi Kohsaka;Etsuko Wada

  • Intracellular signaling in M-CSF-induced microglia activation: role of Iba1.

    Yoshinori Imai;Shinichi Kohsaka

  • Microglial Ramification, Surveillance, and Interleukin-1β Release Are Regulated by the Two-Pore Domain K+ Channel THIK-1

    Christian Madry;Christian Madry;Vasiliki Kyrargyri;I. Lorena Arancibia-Cárcamo;Renaud Jolivet;Renaud Jolivet

  • Microglia: activation and their significance in the central nervous system.

    Kazuyuki Nakajima;Shinichi Kohsaka

  • Microglia/macrophage-specific protein Iba1 binds to fimbrin and enhances its actin-bundling activity.

    Keiko Ohsawa;Yoshinori Imai;Yo Sasaki;Shinichi Kohsaka

  • Iba1 is an actin-cross-linking protein in macrophages/microglia.

    Unknown

  • Microglia turnover with aging and in an Alzheimer's model via long-term in vivo single-cell imaging

    Petra Füger;Petra Füger;Jasmin K Hefendehl;Jasmin K Hefendehl;Karthik Veeraraghavalu;Ann-Christin Wendeln;Ann-Christin Wendeln

  • Immunohistochemical studies on the proliferation of reactive astrocytes and the expression of cytoskeletal proteins following brain injury in rats

    Yoshiaki Takamiya;Shinichi Kohsaka;Shigeo Toya;Mitsuhiro Otani

  • Involvement of P2X4 and P2Y12 receptors in ATP-induced microglial chemotaxis.

    Keiko Ohsawa;Yasuhiro Irino;Yasuko Nakamura;Chihiro Akazawa

  • P2Y12 Receptors in Spinal Microglia Are Required for Neuropathic Pain after Peripheral Nerve Injury

    Hidetoshi Tozaki-Saitoh;Makoto Tsuda;Hiroyuki Miyata;Kazuaki Ueda

  • Homeostatic and injury-induced microglia behavior in the aging brain.

    Jasmin Kim Hefendehl;Jonas J. Neher;Rafael B. Sühs;Shinichi Kohsaka

  • Microglial α7 nicotinic acetylcholine receptors drive a phospholipase C/IP3 pathway and modulate the cell activation toward a neuroprotective role

    Tomohisa Suzuki;Izumi Hide;Akiyo Matsubara;Chihiro Hama

  • Microglia: neuroprotective and neurotrophic cells in the central nervous system.

    Kazuyuki Nakajima;Shinichi Kohsaka

Frequent Co-Authors

Kazuhide Inoue
Kazuhide Inoue Kyushu University
Nobuyuki Takei
Nobuyuki Takei Niigata University
Kotaro Hattori
Kotaro Hattori National Center of Neurology and Psychiatry
Makoto Tsuda
Makoto Tsuda Kyushu University
Yu-ichi Goto
Yu-ichi Goto University of Tsukuba
Hiroshi Nakanishi
Hiroshi Nakanishi Yasuda Women's University
Kazunori Nakajima
Kazunori Nakajima Keio University
Yoshihiro Nakata
Yoshihiro Nakata Hiroshima University
Sachio Takashima
Sachio Takashima Tottori University

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