What is he best known for?
The fields of study he is best known for:
- Gene
- Mutation
- Internal medicine
Genetics, Mitochondrial DNA, Mitochondrion, Mitochondrial myopathy and Molecular biology are his primary areas of study.
He focuses mostly in the field of Mitochondrial DNA, narrowing it down to matters related to Phenotype and, in some cases, DNA.
The various areas that Yu-ichi Goto examines in his Mitochondrion study include RNA interference and Transcription.
His Mitochondrial myopathy research includes themes of Lactic acidosis, Internal medicine, Heteroplasmy and Mutation.
His Lactic acidosis study which covers Encephalopathy that intersects with Pathology.
His studies deal with areas such as Chromatin immunoprecipitation, Myopathy, MECP2 and Gene, Rett syndrome as well as Molecular biology.
His most cited work include:
- A mutation in the tRNA Leu(UUR) gene associated with the MELAS subgroup of mitochondrial encephalomyopathies (1611 citations)
- Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice (718 citations)
- Introduction of disease-related mitochondrial DNA deletions into HeLa cells lacking mitochondrial DNA results in mitochondrial dysfunction. (466 citations)
What are the main themes of his work throughout his whole career to date?
Yu-ichi Goto spends much of his time researching Genetics, Mitochondrial DNA, Internal medicine, Pathology and Molecular biology.
His Gene, Mutation, Point mutation, Heteroplasmy and Mutation investigations are all subjects of Genetics research.
His research in Mitochondrial DNA intersects with topics in Mitochondrion, Cytochrome c oxidase and Mutant.
In his study, Myopathy is strongly linked to Endocrinology, which falls under the umbrella field of Internal medicine.
His studies in Pathology integrate themes in fields like Cortical dysplasia, White matter, Cerebellar ataxia and Kearns–Sayre syndrome.
His Mitochondrial myopathy research is multidisciplinary, incorporating elements of Encephalopathy and Mitochondrial encephalomyopathy.
He most often published in these fields:
- Genetics (37.31%)
- Mitochondrial DNA (29.23%)
- Internal medicine (23.08%)
What were the highlights of his more recent work (between 2014-2021)?
- Genetics (37.31%)
- Internal medicine (23.08%)
- Gene (15.77%)
In recent papers he was focusing on the following fields of study:
His main research concerns Genetics, Internal medicine, Gene, Cell biology and Mitochondrion.
He integrates Genetics and Pelizaeus Merzbacher like disease in his studies.
His biological study spans a wide range of topics, including Gastroenterology, STIM1 and Endocrinology.
His Cell biology research integrates issues from Muscle disorder, Mutation, Protein biosynthesis, Muscular dystrophy and TRNA modification.
His Mitochondrion study also includes fields such as
- Mitochondrial disease, which have a strong connection to Mitochondrial myopathy, Lactic acidosis, RNA and Bicarbonate,
- Induced pluripotent stem cell, Pentose phosphate pathway, Heteroplasmy and Mutant most often made with reference to Oxidative phosphorylation.
His studies deal with areas such as Oxidative stress and Encephalopathy as well as Mitochondrial DNA.
Between 2014 and 2021, his most popular works were:
- Dominant mutations in ORAI1 cause tubular aggregate myopathy with hypocalcemia via constitutive activation of store-operated Ca2+ channels (95 citations)
- Higd1a is a positive regulator of cytochrome c oxidase (60 citations)
- Plasma Metabolites Predict Severity of Depression and Suicidal Ideation in Psychiatric Patients-A Multicenter Pilot Analysis. (57 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Mutation
- Internal medicine
His primary scientific interests are in Genetics, Internal medicine, Mitochondrion, Gastroenterology and Molecular biology.
Yu-ichi Goto frequently studies issues relating to White matter and Internal medicine.
His Mitochondrion research includes themes of Oxidative phosphorylation, Heteroplasmy and Mitochondrial disease.
Yu-ichi Goto has researched Gastroenterology in several fields, including Odds ratio, Taurine, Cohort study and Cohort.
The Molecular biology study combines topics in areas such as Compound heterozygosity, Pyruvate dehydrogenase complex and Induced pluripotent stem cell.
His work in Cell biology tackles topics such as Endocrinology which are related to areas like Mutation.
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