Ikuya Nonaka

Research.com Recognitions

• 2025 - Research.com Biology and Biochemistry in Japan Leader Award

Overview

Best Publications

• A mutation in the tRNA Leu(UUR) gene associated with the MELAS subgroup of mitochondrial encephalomyopathies

  Yu-Ichi Goto;Ikuya Nonaka;Satoshi Horai

  2894
  Citations

• Myogenin gene disruption results in perinatal lethality because of severe muscle defect

  Yoko Nabeshima;Kazunori Hanaoka;Michiko Hayasaka;Eisaku Esuml

  1299
  Citations

• Mitochondrial DNA Deletions in Progressive External Ophthalmoplegia and Kearns-Sayre Syndrome

  Carlos T. Moraes;Salvatore Dimauro;Massimo Zeviani;Anne Lombes

  1198
  Citations

• Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice

  Naotada Ishihara;Masatoshi Nomura;Akihiro Jofuku;Hiroki Kato

  1135
  Citations

• Primary LAMP-2 deficiency causes X-linked vacuolar cardiomyopathy and myopathy (Danon disease)

  Ichizo Nishino;Jin Fu;Kurenai Tanji;Takeshi Yamada

  1058
  Citations

• An ancient retrotransposal insertion causes Fukuyama-type congenital muscular dystrophy

  Kazuhiro Kobayashi;Yutaka Nakahori;Masashi Miyake;Kiichiro Matsumura

  949
  Citations

• A subtype of diabetes mellitus associated with a mutation of mitochondrial DNA

  T Kadowaki;H Kadowaki;Y Mori;K Tobe

  762
  Citations

• Introduction of disease-related mitochondrial DNA deletions into HeLa cells lacking mitochondrial DNA results in mitochondrial dysfunction.

  Jun-Ichi Hayashi;Shigeo Ohta;Aiko Kikuchi;Masakazu Takemitsu

  748
  Citations

• Immunostaining of skeletal and cardiac muscle surface membrane with antibody against Duchenne muscular dystrophy peptide.

  K Arahata;S Ishiura;T Ishiguro;T Tsukahara

  704
  Citations

• MELAS mutation in mtDNA binding site for transcription termination factor causes defects in protein synthesis and in respiration but no change in levels of upstream and downstream mature transcripts.

  A. Chomyn;A. Martinuzzi;M. Yoneda;A. Daga

  668
  Citations

• Mutations in the dystrophin-associated protein γ-sarcoglycan in chromosome 13 muscular dystrophy

  Satoru Noguchi;Elizabeth M. McNally;Kamel Ben Othmane;Yasuko Hagiwara

  643
  Citations

• Inter-mitochondrial complementation: Mitochondria-specific system preventing mice from expression of disease phenotypes by mutant mtDNA

  Kazuto Nakada;Kimiko Inoue;Kimiko Inoue;Tomoko Ono;Kotoyo Isobe

  600
  Citations

• Generation of mice with mitochondrial dysfunction by introducing mouse mtDNA carrying a deletion into zygotes

  Kimiko Inoue;Kazuto Nakada;Atsuo Ogura;Kotoyo Isobe

  540
  Citations

• Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke‐like episodes (MELAS) A correlative study of the clinical features and mitochondrial DNA mutation

  Y. Goto;S. Horai;T. Matsuoka;Y. Koga

  537
  Citations

• Mutations in the integrin alpha7 gene cause congenital myopathy.

  Yukiko K. Hayashi;Fan-Li Chou;Eva Engvall;Megumu Ogawa

  447
  Citations

• A new mtDNA mutation associated with mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS).

  Yu-ichi Goto;Ikuya Nonaka;Satoshi Horai

  445
  Citations

• Mitochondrial neurogastrointestinal encephalomyopathy: An autosomal recessive disorder due to thymidine phosphorylase mutations

  I Nishino;A Spinazzola;A Papadimitriou;S Hammans

  397
  Citations

• Familial distal myopathy with rimmed vacuole and lamellar (myeloid) body formation.

  Ikuya Nonaka;Nobuhiko Sunohara;Shoichi Ishiura;Eijiro Satoyoshi

  360
  Citations

• Laminin α2 chain-null mutant mice by targeted disruption of the Lama2 gene: a new model of merosin (laminin 2)-deficient congenital muscular dystrophy

  Yuko Miyagoe;Kazunori Hanaoka;Ikuya Nonaka;Michiko Hayasaka

  355
  Citations

• Localization of a gene for Fukuyama type congenital muscular dystrophy to chromosome 9q31-33

  T. Toda;M. Segawa;Y. Nomura;I. Nonaka

  329
  Citations