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Shoichi Ishiura

Shoichi Ishiura

D-Index & Metrics

Biology and Biochemistry

D-Index
78
Citations
19323
World Ranking
4604
National Ranking
304

Overview

Shoichi Ishiura is a researcher affiliated with the University of Tokyo in Japan. Their work primarily focuses on the intersections of neuroscience and medicine, with a particular emphasis on cellular and molecular neuroscience as well as neurology.

The scientist's research topics include:

  • Genetic Neurodegenerative Diseases
  • Neurological disorders and treatments
  • Nerve injury and regeneration

They have contributed scholarly articles on these topics, with publications recorded in venues such as Methods in Molecular Biology. One identified publication from 2025 is titled "Exon Skipping by Ultrasound-Enhanced Delivery of Morpholino with Bubble Liposomes for Myotonic Dystrophy Model Mice", published in Methods in Molecular Biology.

Collaborations have been noted with several co-authors, including:

  • Yoichi Negishi
  • Yoko Endo-Takahashi

The research undertaken by Shoichi Ishiura addresses mechanisms underlying neurodegenerative diseases, focusing on molecular techniques and therapeutic approaches such as exon skipping facilitated by innovative delivery methods. This aligns with their expertise in neurological disorders, therapeutic interventions, and cellular neurobiology.

Best Publications

  • Structure and physiological function of calpains

    Hiroyuki Sorimachi;Shoichi Ishiura;Koichi Suzuki

  • Immunostaining of skeletal and cardiac muscle surface membrane with antibody against Duchenne muscular dystrophy peptide.

    K Arahata;S Ishiura;T Ishiguro;T Tsukahara

  • The VNTR polymorphism of the human dopamine transporter (DAT1) gene affects gene expression.

    S Fuke;S Suo;N Takahashi;H Koike

  • Muscle-specific Calpain, p94, Responsible for Limb Girdle Muscular Dystrophy Type 2A, Associates with Connectin through IS2, a p94-specific Sequence

    Hiroyuki Sorimachi;Kayoko Kinbara;Sumiko Kimura;Miwako Takahashi

  • Putative function of ADAM9, ADAM10, and ADAM17 as APP -secretase

    Masashi Asai;Chinatsu Hattori;Beáta Szabó;Noboru Sasagawa

  • Membrane-anchored metalloprotease MDC9 has an alpha-secretase activity responsible for processing the amyloid precursor protein.

    Hisashi Koike;Shigeo Tomioka;Hiroyuki Sorimachi;Takaomi C. Saido

  • Familial distal myopathy with rimmed vacuole and lamellar (myeloid) body formation.

    Ikuya Nonaka;Nobuhiko Sunohara;Shoichi Ishiura;Eijiro Satoyoshi

  • Muscle-specific calpain, p94, is degraded by autolysis immediately after translation, resulting in disappearance from muscle.

    H. Sorimachi;N. Toyama-Sorimachi;T. C. Saido;H. Kawasaki

  • Expansions of intronic TTTCA and TTTTA repeats in benign adult familial myoclonic epilepsy.

    Hiroyuki Ishiura;Koichiro Doi;Jun Mitsui;Jun Yoshimura

  • Calpain: novel family members, activation, and physiologic function.

    K Suzuki;H Sorimachi;T Yoshizawa;K Kinbara

  • Studies of a calcium-activated neutral protease from chicken skeletal muscle. I. Purification and characterization.

    Shoichi Ishiura;Hiromu Murofushi;Koichi Suzuki;Kazutomo Imahori

  • Tissue-specific expression and alpha-actinin binding properties of the Z-disc titin: implications for the nature of vertebrate Z-discs

    H. Sorimachi;A. Freiburg;Bernhard Kolmerer;S. Ishiura

  • Muscleblind protein, MBNL1/EXP, binds specifically to CHHG repeats

    Yoshihiro Kino;Daisuke Mori;Yoko Oma;Yuya Takeshita

  • Berberine alters the processing of Alzheimer's amyloid precursor protein to decrease Aβ secretion

    Masashi Asai;Nobuhisa Iwata;Ayumu Yoshikawa;Yoshimi Aizaki

  • A novel tissue-specific calpain species expressed predominantly in the stomach comprises two alternative splicing products with and without Ca(2+)-binding domain.

    H Sorimachi;S Ishiura;K Suzuki

  • Functional Defects of a Muscle-specific Calpain, p94, Caused by Mutations Associated with Limb-Girdle Muscular Dystrophy Type 2A

    Yasuko Ono;Hiroko Shimada;Hiroyuki Sorimachi;Isabelle Richard

  • The novel β-secretase inhibitor KMI-429 reduces amyloid β peptide production in amyloid precursor protein transgenic and wild-type mice

    Masashi Asai;Chinatsu Hattori;Nobuhisa Iwata;Takaomi C. Saido

  • Potential link between amyloid beta-protein 42 and C-terminal fragment gamma 49-99 of beta-amyloid precursor protein.

    Toru Sato;Naoshi Dohmae;Yue Qi;Nobuto Kakuda

  • Interaction between emerin and nuclear lamins.

    Masayo Sakaki;Hisashi Koike;Nobuhiro Takahashi;Noboru Sasagawa

  • MKBP, a Novel Member of the Small Heat Shock Protein Family, Binds and Activates the Myotonic Dystrophy Protein Kinase

    Atsushi Suzuki;Yuki Sugiyama;Yukiko Hayashi;Nobuo Nyu-i

Frequent Co-Authors

Koichi Suzuki
Koichi Suzuki University of Tokyo
Hiroyuki Sorimachi
Hiroyuki Sorimachi Tokyo Metropolitan Institute of Medical Science
Ikuya Nonaka
Ikuya Nonaka Tokyo Medical University
Yoshiaki Kiso
Yoshiaki Kiso Nagahama Institute of Bio-Science and Technology
Takaomi C. Saido
Takaomi C. Saido RIKEN Center for Brain Science
Makoto Asashima
Makoto Asashima Teikyo University
Ichizo Nishino
Ichizo Nishino Tokyo Medical University
Shigeo Ohno
Shigeo Ohno Yokohama City University
Nobuhisa Iwata
Nobuhisa Iwata Nagasaki University
Hiroshi Kawasaki
Hiroshi Kawasaki Keio University

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