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Gavin William Grahame Wilkinson

Gavin William Grahame Wilkinson

D-Index & Metrics

Microbiology

D-Index
64
Citations
13442
World Ranking
2631
National Ranking
227

Overview

Gavin William Grahame Wilkinson is affiliated with Cardiff University in the United Kingdom. Their research primarily spans across multiple fields including Medicine and Immunology and Microbiology, with significant contributions to Epidemiology, Parasitology, Immunology, Virology, and Genetics.

The scientist has focused extensively on topics related to Cytomegalovirus and herpesvirus research, Herpesvirus Infections and Treatments, and Toxoplasma gondii Research Studies. Their work also covers areas such as Immune Cell Function and Interaction, Virus-based gene therapy research, HIV Research and Treatment, and Poxvirus research and outbreaks.

Gavin William Grahame Wilkinson has a consistent record of publications in notable scientific venues, including:

  • Proceedings of the National Academy of Sciences
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Clinical Investigation
  • Journal of General Virology
  • Access Microbiology

The scientist's recent papers demonstrate a focus on viral immunology and host-virus interactions. These include:

  • Monoclonal antibodies targeting nonstructural viral antigens can activate ADCC against human cytomegalovirus, 2021, Journal of Clinical Investigation
  • ADAM17 targeting by human cytomegalovirus remodels the cell surface proteome to simultaneously regulate multiple immune pathways, 2023, Proceedings of the National Academy of Sciences
  • HCMV-secreted glycoprotein gpUL4 inhibits TRAIL-mediated apoptosis and NK cell activation, 2023, Proceedings of the National Academy of Sciences
  • Downregulation of HLA-I by the molluscum contagiosum virus mc080 impacts NK-cell recognition and promotes CD8+ T-cell evasion, 2020, Journal of General Virology
  • Virion Proteomics of Genetically Intact HCMV Reveals a Novel Regulator of Envelope Glycoprotein Composition that Protects Against Humoral Immunity, 2024, bioRxiv (Cold Spring Harbor Laboratory)

Collaborative work is a notable aspect of their research, frequently working with coauthors such as Eddie C. Y. Wang, Richard J. Stanton, Michael P. Weekes, Ceri A. Fielding, and Virginia-Maria Vlahava.

Best Publications

  • Surface Expression of HLA-E, an Inhibitor of Natural Killer Cells, Enhanced by Human Cytomegalovirus gpUL40

    Peter Tomasec;Veronique M. Braud;Carole Rickards;Martin B. Powell

  • Genetic content of wild-type human cytomegalovirus

    Aidan Dolan;Charles Cunningham;Ralph D. Hector;Aycan F. Hassan-Walker

  • A recombinant vaccinia virus encoding human papillomavirus types 16 and 18, E6 and E7 proteins as immunotherapy for cervical cancer

    L.K Borysiewicz;A Fiander;M Nimako;S Man

  • Construction and properties of a mutant of herpes simplex virus type 1 with glycoprotein H coding sequences deleted.

    Audrey Forrester;Helen Farrell;Gavin Wilkinson;Jane Kaye

  • Quantitative temporal viromics: an approach to investigate host-pathogen interaction.

    Michael P. Weekes;Michael P. Weekes;Peter Tomasec;Edward L. Huttlin;Ceri Alan Fielding

  • NF-kappa B activation of the cytomegalovirus enhancer is mediated by a viral transactivator and by T cell stimulation.

    L. C. Sambucetti;J. M. Cherrington;G. W. G. Wilkinson;E. S. Mocarski

  • The human cytomegalovirus US6 glycoprotein inhibits transporter associated with antigen processing-dependent peptide translocation

    Paul J. Lehner;Jaana T. Karttunen;Gavin W. G. Wilkinson;Peter Cresswell

  • Downregulation of natural killer cell–activating ligand CD155 by human cytomegalovirus UL141

    Peter Tomasec;Edward Chung Yern Wang;Andrew J. Davison;Borivoj Vojtesek

  • Complex I Binding by a Virally Encoded RNA Regulates Mitochondria-Induced Cell Death

    Matthew B. Reeves;Matthew B. Reeves;Andrew A. Davies;Andrew A. Davies;Brian Patrick McSharry;Brian Patrick McSharry;Gavin William Grahame Wilkinson;Gavin William Grahame Wilkinson

  • Modulation of natural killer cells by human cytomegalovirus

    Gavin William Grahame Wilkinson;Peter Tomasec;Richard James Stanton;Melanie Armstrong

  • Reconstruction of the complete human cytomegalovirus genome in a BAC reveals RL13 to be a potent inhibitor of replication

    Richard J. Stanton;Katarina Baluchova;Derrick J. Dargan;Charles Cunningham

  • Constitutive and enhanced expression from the CMV major IE promoter in a defective adenovirus vector.

    Gavin W.G. Wilkinson;Alan Akrigg

  • High-resolution human cytomegalovirus transcriptome

    Derek Gatherer;Sepher Seirafian;Charles Cunningham;Mary Holton

  • Sequential mutations associated with adaptation of human cytomegalovirus to growth in cell culture

    Derrick J. Dargan;Elaine Douglas;Charles Cunningham;Fiona Jamieson

  • The structure of the major immediate early gene of human cytomegalovirus strain AD169.

    A. Akrigg;G.W.G. Wilkinson;J.D. Oram

  • UL40-mediated NK evasion during productive infection with human cytomegalovirus

    Edward Chung Yern Wang;Brian Patrick McSharry;Christelle Retiere;Peter Tomasec

  • Human Daxx-mediated Repression of Human Cytomegalovirus Gene Expression Correlates with a Repressive Chromatin Structure around the Major Immediate Early Promoter

    David L. Woodhall;Ian J. Groves;Matthew B. Reeves;Gavin W. Wilkinson

  • Human Cytomegalovirus Encodes an MHC Class I-Like Molecule (UL142) That Functions to Inhibit NK Cell Lysis

    Mark R. Wills;Omodele Ashiru;Matthew B. Reeves;Georgina Okecha

  • Disruption of PML-associated nuclear bodies mediated by the human cytomegalovirus major immediate early gene product.

    Gavin W. G. Wilkinson;Collette Kelly;John H. Sinclair;Carole Rickards

  • The human cytomegalovirus MHC class I homolog UL18 inhibits LIR-1+ but activates LIR-1- NK cells.

    Virginie Prod'homme;Cora Griffin;Rebecca Aicheler;Edward Chung Yern Wang

Frequent Co-Authors

Andrew J. Davison
Andrew J. Davison University of Glasgow
Edward Chung Yern Wang
Edward Chung Yern Wang Cardiff University
Paul J. Lehner
Paul J. Lehner University of Cambridge
Robin Antrobus
Robin Antrobus University of Cambridge
Pedro R. Lowenstein
Pedro R. Lowenstein University of Michigan–Ann Arbor
Maria G. Castro
Maria G. Castro University of Michigan–Ann Arbor
Vincent C. Emery
Vincent C. Emery University of Surrey
Anthony K. Campbell
Anthony K. Campbell Cardiff University
Paul D. Griffiths
Paul D. Griffiths University College London
Giuseppe Gerna
Giuseppe Gerna University of Pavia

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