Paul J. Lehner

Research.com Recognitions

• Fellow of The Academy of Medical Sciences, United Kingdom
• Member of the European Molecular Biology Organization (EMBO)
• Fellow of The Academy of Medical Sciences, United Kingdom
• Member of the European Molecular Biology Organization (EMBO)
• Fellow of The Academy of Medical Sciences, United Kingdom
• Member of the European Molecular Biology Organization (EMBO)

Overview

Best Publications

• SARS-CoV-2 evolution during treatment of chronic infection.

  Steven A. Kemp;Dami A. Collier;Dami A. Collier;Rawlings P. Datir;Isabella A. T. M. Ferreira

  973
  Citations

• CMTM6 maintains the expression of PD-L1 and regulates anti-tumour immunity

  Marian L Burr;Marian L Burr;Marian L Burr;Christina E Sparbier;Yih-Chih Chan;James C Williamson

  930
  Citations

• Roles for Calreticulin and a Novel Glycoprotein, Tapasin, in the Interaction of MHC Class I Molecules with TAP

  Bhanu Sadasivan;Paul J Lehner;Bodo Ortmann;Thomas Spies

  912
  Citations

• Age-related immune response heterogeneity to SARS-CoV-2 vaccine BNT162b2.

  Dami A Collier;Dami A Collier;Isabella A T M Ferreira;Prasanti Kotagiri;Rawlings P Datir;Rawlings P Datir

  749
  Citations

• A critical role for tapasin in the assembly and function of multimeric MHC class I-TAP complexes.

  Bodo Ortmann;James Copeman;Paul J. Lehner;Bhanu Sadasivan

  674
  Citations

• Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies.

  Dami A. Collier;Dami A. Collier;Anna De Marco;Isabella A. T. M. Ferreira;Bo Meng

  656
  Citations

• Screening of healthcare workers for SARS-CoV-2 highlights the role of asymptomatic carriage in COVID-19 transmission.

  Lucy Rivett;Lucy Rivett;Sushmita Sridhar;Sushmita Sridhar;Dominic Sparkes;Dominic Sparkes;Matthew Routledge;Matthew Routledge

  583
  Citations

• Quantitative temporal viromics: an approach to investigate host-pathogen interaction.

  Michael P. Weekes;Michael P. Weekes;Peter Tomasec;Edward L. Huttlin;Ceri Alan Fielding

  508
  Citations

• Latency, chromatin remodeling, and reactivation of human cytomegalovirus in the dendritic cells of healthy carriers.

  M. B. Reeves;P. A. MacAry;P. J. Lehner;J. G. P. Sissons

  488
  Citations

• An Evolutionarily Conserved Function of Polycomb Silences the MHC Class I Antigen Presentation Pathway and Enables Immune Evasion in Cancer

  Marian L. Burr;Marian L. Burr;Marian L. Burr;Christina E. Sparbier;Christina E. Sparbier;Kah Lok Chan;Kah Lok Chan;Yih-Chih Chan

  475
  Citations

• NOTCH1 mediates a switch between two distinct secretomes during senescence

  Matthew William Hoare;Yoko Ito;Tae-Won Kang;Michael Paul Weekes

  452
  Citations

• Loss of function of a lupus-associated FcgammaRIIb polymorphism through exclusion from lipid rafts.

  R Andres Floto;Menna R Clatworthy;Karen R Heilbronn;Dalya R Rosner

  390
  Citations

• The human cytomegalovirus US6 glycoprotein inhibits transporter associated with antigen processing-dependent peptide translocation

  Paul J. Lehner;Jaana T. Karttunen;Gavin W. G. Wilkinson;Peter Cresswell

  375
  Citations

• Soluble Tapasin Restores MHC Class I Expression and Function in the Tapasin-Negative Cell Line .220

  Paul J Lehner;Michael J Surman;Peter Cresswell

  367
  Citations

• CD40 is a cellular receptor mediating mycobacterial heat shock protein 70 stimulation of CC-chemokines.

  Yufei Wang;Charles G. Kelly;Jaana T. Karttunen;Trevor Whittall

  343
  Citations

• Lysine-63-linked ubiquitination is required for endolysosomal degradation of class I molecules.

  Lidia M Duncan;Siân Piper;Roger B Dodd;Mark K Saville

  343
  Citations

• Longitudinal analysis reveals that delayed bystander CD8+ T cell activation and early immune pathology distinguish severe COVID-19 from mild disease.

  Laura Bergamaschi;Federica Mescia;Lorinda Turner;Aimee L. Hanson

  340
  Citations

• Human HLA-A0201-restricted cytotoxic T lymphocyte recognition of influenza A is dominated by T cells bearing the V beta 17 gene segment.

  Paul J. Lehner;Eddie C. Y. Wang;Paul A. H. Moss;Sheila Williams

  322
  Citations

• Epigenetic silencing by the HUSH complex mediates position-effect variegation in human cells

  Iva A. Tchasovnikarova;Richard T. Timms;Nicholas J. Matheson;Kim Wals

  296
  Citations

• Inhibition of MHC class I-restricted antigen presentation by gamma 2-herpesviruses.

  Philip G. Stevenson;Stacey Efstathiou;Peter C. Doherty;Paul J. Lehner

  264
  Citations