World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
69
Citations
17124
World Ranking
2506
National Ranking
172

Overview

Hartmut Hengel is affiliated with the University of Freiburg in Germany and has an extensive publication record primarily in medicine and immunology. The research work by Hengel covers various subfields, including epidemiology, immunology, infectious diseases, genetics, and radiology, nuclear medicine, and imaging.

The scientist's research topics include:

  • Cytomegalovirus and herpesvirus research
  • SARS-CoV-2 and COVID-19 research
  • Immune cell function and interaction
  • Herpesvirus infections and treatments
  • T-cell and B-cell immunology
  • Monoclonal and polyclonal antibodies research
  • SARS-CoV-2 detection and testing

Recent publications by Hengel include:

  • "Class switch toward noninflammatory, spike-specific IgG4 antibodies after repeated SARS-CoV-2 mRNA vaccination," 2022, published in Science Immunology
  • "Pharmacological Inhibition of Acid Sphingomyelinase Prevents Uptake of SARS-CoV-2 by Epithelial Cells," 2020, published in Cell Reports Medicine
  • "Prevalence of SARS-CoV-2 Infection in Children and Their Parents in Southwest Germany," 2021, published in JAMA Pediatrics
  • "Robust and durable serological response following pediatric SARS-CoV-2 infection," 2022, published in Nature Communications
  • "Cytomegalovirus subverts macrophage identity," 2021, published in Cell

Frequent coauthors collaborating with Hengel include Philipp Kolb, Daniela Huzly, Katja Hoffmann, Valeria Falcone, and Marcus Panning.

Hengel's publications are often featured in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Frontiers in Immunology
  • Nature Communications
  • eLife
  • SSRN Electronic Journal

Best Publications

  • Host immune system gene targeting by a viral miRNA.

    Noam Stern-Ginossar;Naama Elefant;Albert Zimmermann;Dana G. Wolf

  • Decoding Human Cytomegalovirus

    Noam Stern-Ginossar;Ben Weisburd;Annette Michalski;Vu Thuy Khanh Le

  • Memory Inflation: Continuous Accumulation of Antiviral CD8+ T Cells Over Time

    Urs Karrer;Sophie Sierro;Markus Wagner;Annette Oxenius

  • Expansion of CD94/NKG2C+ NK cells in response to human cytomegalovirus-infected fibroblasts

    Mónica Gumá;Matthias Budt;Andrea Sáez;Tamara Brckalo

  • Cloning and sequencing of a highly productive, endotheliotropic virus strain derived from human cytomegalovirus TB40/E.

    Christian Sinzger;Gabriele Hahn;Margarete Digel;Ruth Katona

  • Hierarchical and redundant lymphocyte subset control precludes cytomegalovirus replication during latent infection

    Bojan Polić;Hartmut Hengel;Astrid Krmpotić;Joanne Trgovcich

  • A viral ER resident glycoprotein inactivates the MHC encoded peptide transporter.

    Hartmut Hengel;Jens Oliver Koopmann;Thomas Flohr;Walter Muranyi

  • Cutting Edge: The Human Cytomegalovirus UL40 Gene Product Contains a Ligand for HLA-E and Prevents NK Cell-Mediated Lysis

    Matthias Ulbrecht;Silvia Martinozzi;Mariola Grzeschik;Hartmut Hengel

  • A Mouse Cytomegalovirus Glycoprotein Retains MHC Class I Complexes in the ERGIC/cis-Golgi Compartments

    Heike Ziegler;Regine Thäle;Pero Lucin;Walter Muranyi

  • Recent bacterial and viral infection is a risk factor for cerebrovascular ischemia: Clinical and biochemical studies

    A. J. Grau;F. Buggle;H. Becher;E. Zimmermann

  • A Novel Human Polyomavirus Closely Related to the African Green Monkey-Derived Lymphotropic Polyomavirus

    Nelly Scuda;Jörg Hofmann;Sébastien Calvignac-Spencer;Klemens Ruprecht

  • Class switch towards non-inflammatory, spike-specific IgG4 antibodies after repeated SARS-CoV-2 mRNA vaccination

    Unknown

  • A cytomegalovirus glycoprotein re‐routes MHC class I complexes to lysosomes for degradation

    Uwe Reusch;Walter Muranyi;Pero Lucin;Hans‐Gerhard Burgert

  • Immune evasion by cytomegalovirus--survival strategies of a highly adapted opportunist.

    Hartmut Hengel;Wolfram Brune;Ulrich H Koszinowski

  • Cytomegalovirus prevents antigen presentation by blocking the transport of peptide-loaded major histocompatibility complex class I molecules into the medial-Golgi compartment.

    M del Val;H Hengel;H Häcker;U Hartlaub

  • MCMV glycoprotein gp40 confers virus resistance to CD8+ T cells and NK cells in vivo.

    Astrid Krmpotić;Dirk H. Busch;Ivan Bubić;Friedemann Gebhardt

  • Enforced viral replication activates adaptive immunity and is essential for the control of a cytopathic virus.

    Nadine Honke;Namir Shaabani;Giuseppe Cadeddu;Ursula R Sorg

  • Identification and expression of human cytomegalovirus transcription units coding for two distinct Fcγ receptor homologs

    Ramazan Atalay;Albert Zimmermann;Markus Wagner;Eva Borst

  • IL-12–producing monocytes and HLA-E control HCMV-driven NKG2C + NK cell expansion

    Alexander Rölle;Julia Pollmann;Eva Maria Ewen;Vu Thuy Khanh Le

  • A cytomegaloviral protein reveals a dual role for STAT2 in IFN-γ signaling and antiviral responses

    Albert Zimmermann;Mirko Trilling;Markus Wagner;Manuel Wilborn

  • Late phase inhibition of murine cytomegalovirus replication by synergistic action of interferon-gamma and tumour necrosis factor.

    Pero Lučin;Stipan Jonjić;Martin Messerle;Bojan Polić

Frequent Co-Authors

Ulrich H. Koszinowski
Ulrich H. Koszinowski Ludwig-Maximilians-Universität München
Stipan Jonjić
Stipan Jonjić University of Rijeka
Frank Momburg
Frank Momburg German Cancer Research Center
Dieter Häussinger
Dieter Häussinger Heinrich Heine University Düsseldorf
Martin Messerle
Martin Messerle Hannover Medical School
Philipp A. Lang
Philipp A. Lang Heinrich Heine University Düsseldorf
Thomas Ruppert
Thomas Ruppert Heidelberg University
Karl S. Lang
Karl S. Lang University of Duisburg-Essen
Ofer Mandelboim
Ofer Mandelboim Hebrew University of Jerusalem

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