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Emmanuel J. H. J. Wiertz

Emmanuel J. H. J. Wiertz

D-Index & Metrics

Microbiology

D-Index
65
Citations
15470
World Ranking
2501
National Ranking
102

Emmanuel J. H. J. Wiertz publication distribution in Microbiology in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Microbiology in 2026. The highlighted bar marks where Emmanuel J. H. J. Wiertz sits on this spectrum.

55–64 publications: 8 scientists 65–74 publications: 29 scientists 75–84 publications: 55 scientists 85–94 publications: 112 scientists 95–104 publications: 137 scientists 105–114 publications: 190 scientists 115–124 publications: 235 scientists 125–134 publications: 234 scientists 135–144 publications: 288 scientists 145–154 publications: 264 scientists 155–164 publications: 264 scientists 165–174 publications: 253 scientists 175–184 publications: 276 scientists 185–194 publications: 190 scientists 195–204 publications: 233 scientists 205–214 publications: 207 scientists 215–224 publications: 198 scientists 225–234 publications: 155 scientists 235–244 publications: 161 scientists 245–254 publications: 160 scientists 255–264 publications: 146 scientists 265–274 publications: 139 scientists 275–284 publications: 148 scientists 285–294 publications: 115 scientists 295–304 publications: 96 scientists 305–314 publications: 88 scientists 315–324 publications: 106 scientists 325–334 publications: 65 scientists 335–344 publications: 76 scientists 345–354 publications: 64 scientists 355–364 publications: 62 scientists 365–374 publications: 65 scientists 375–384 publications: 61 scientists 385–394 publications: 34 scientists 395–404 publications: 44 scientists 405–414 publications: 36 scientists 415–424 publications: 35 scientists 425–434 publications: 29 scientists 435–444 publications: 33 scientists 445–454 publications: 34 scientists 455–464 publications: 25 scientists 465–474 publications: 26 scientists 475–484 publications: 20 scientists 485–494 publications: 19 scientists 495–504 publications: 16 scientists 505–514 publications: 17 scientists 515–524 publications: 23 scientists 525–534 publications: 14 scientists 535–544 publications: 14 scientists 545–554 publications: 18 scientists 555–564 publications: 12 scientists 565–574 publications: 7 scientists 575–584 publications: 9 scientists 585–594 publications: 9 scientists 595–604 publications: 9 scientists 605–614 publications: 7 scientists 615–624 publications: 9 scientists 625–634 publications: 7 scientists 635–644 publications: 4 scientists 645–654 publications: 5 scientists 655–664 publications: 6 scientists 665–674 publications: 7 scientists 675–678 publications: 3 scientists 679+ publications: 99 scientists
55 publications 679+

This scientist: 169 publications — 35th percentile

35% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 679 publications or more.

Emmanuel J. H. J. Wiertz D-index placement in Microbiology in 2026

The chart shows the D-index (discipline H-index) distribution of Microbiology scientists ranked by Research.com in 2026. The highlighted bar marks where Emmanuel J. H. J. Wiertz sits on this spectrum.

40 D-Index: 30 scientists 41 D-Index: 86 scientists 42 D-Index: 90 scientists 43 D-Index: 117 scientists 44 D-Index: 122 scientists 45 D-Index: 123 scientists 46 D-Index: 108 scientists 47 D-Index: 110 scientists 48 D-Index: 106 scientists 49 D-Index: 109 scientists 50 D-Index: 129 scientists 51 D-Index: 111 scientists 52 D-Index: 116 scientists 53 D-Index: 127 scientists 54 D-Index: 134 scientists 55 D-Index: 134 scientists 56 D-Index: 111 scientists 57 D-Index: 136 scientists 58 D-Index: 162 scientists 59 D-Index: 151 scientists 60 D-Index: 139 scientists 61 D-Index: 122 scientists 62 D-Index: 126 scientists 63 D-Index: 144 scientists 64 D-Index: 109 scientists 65 D-Index: 103 scientists 66 D-Index: 124 scientists 67 D-Index: 112 scientists 68 D-Index: 103 scientists 69 D-Index: 131 scientists 70 D-Index: 93 scientists 71 D-Index: 93 scientists 72 D-Index: 96 scientists 73 D-Index: 92 scientists 74 D-Index: 80 scientists 75 D-Index: 66 scientists 76 D-Index: 87 scientists 77 D-Index: 60 scientists 78 D-Index: 73 scientists 79 D-Index: 59 scientists 80 D-Index: 57 scientists 81 D-Index: 55 scientists 82 D-Index: 47 scientists 83 D-Index: 77 scientists 84 D-Index: 50 scientists 85 D-Index: 45 scientists 86 D-Index: 42 scientists 87 D-Index: 41 scientists 88 D-Index: 32 scientists 89 D-Index: 38 scientists 90 D-Index: 35 scientists 91 D-Index: 34 scientists 92 D-Index: 27 scientists 93 D-Index: 26 scientists 94 D-Index: 33 scientists 95 D-Index: 22 scientists 96 D-Index: 37 scientists 97 D-Index: 22 scientists 98 D-Index: 21 scientists 99 D-Index: 22 scientists 100 D-Index: 30 scientists 101 D-Index: 16 scientists 102 D-Index: 20 scientists 103 D-Index: 17 scientists 104 D-Index: 19 scientists 105 D-Index: 16 scientists 106 D-Index: 19 scientists 107 D-Index: 18 scientists 108 D-Index: 14 scientists 109 D-Index: 10 scientists 110 D-Index: 9 scientists 111 D-Index: 7 scientists 112 D-Index: 11 scientists 113 D-Index: 6 scientists 114 D-Index: 15 scientists 115 D-Index: 10 scientists 116 D-Index: 12 scientists 117 D-Index: 7 scientists 118 D-Index: 10 scientists 119 D-Index: 10 scientists 120 D-Index: 11 scientists 121 D-Index: 2 scientists 122 D-Index: 7 scientists 123 D-Index: 12 scientists 124 D-Index: 5 scientists 125 D-Index: 9 scientists 126 D-Index: 6 scientists 127+ D-Index: 95 scientists
40 D-Index 127+

This scientist: 65 D-Index — 55th percentile

55% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 127 D-Index or more.

Overview

Emmanuel J. H. J. Wiertz is affiliated with Utrecht University in the Netherlands. Their research spans fields primarily centered on Biochemistry, Genetics and Molecular Biology, and Medicine. Within these broad areas, the scientist has contributed extensively to Cell Biology, Epidemiology, Molecular Biology, Infectious Diseases, and Genetics.

The scientist's work covers several specialized research topics, notably:

  • Endoplasmic Reticulum Stress and Disease
  • Herpesvirus Infections and Treatments
  • Immunotherapy and Immune Responses
  • SARS-CoV-2 and COVID-19 Research
  • COVID-19 Clinical Research Studies
  • Protein Degradation and Inhibitors
  • Cytomegalovirus and herpesvirus research

Emmanuel J. H. J. Wiertz has published papers in a variety of scientific journals. Frequent venues include:

  • Molecular Cell
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal for ImmunoTherapy of Cancer
  • Proceedings of the National Academy of Sciences
  • Cells

Several key recent publications illustrate the scope of their research:

  • "Quality Control of ER Membrane Proteins by the RNF185/Membralin Ubiquitin Ligase Complex" (2020) in Molecular Cell
  • "Enhanced antigen cross-presentation in human colorectal cancer-associated fibroblasts through upregulation of the lysosomal protease cathepsin S" (2022) in Journal for ImmunoTherapy of Cancer
  • "A class II MHC-targeted vaccine elicits immunity against SARS-CoV-2 and its variants" (2021) in Proceedings of the National Academy of Sciences
  • "A Broad-Spectrum Antiviral Peptide Blocks Infection of Viruses by Binding to Phosphatidylserine in the Viral Envelope" (2020) in Cells
  • "Quality Control of ER Membrane Proteins by the RNF185/Membralin Ubiquitin Ligase Complex" (2020) in Molecular Cell

The scientist collaborates frequently with several coauthors, including:

  • Robert Jan Lebbink
  • Michael L. van de Weijer
  • Ana I. Costa
  • Peter A. van Veelen
  • Patrique Praest

Best Publications

  • Sec61-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction.

    Emmanuel J. H. J. Wiertz;Domenico Tortorella;Matthew Bogyo;Joyce Yu

  • The Human Cytomegalovirus US11 Gene Product Dislocates MHC Class I Heavy Chains from the Endoplasmic Reticulum to the Cytosol

    Emmanuel J.H.J Wiertz;Thomas R Jones;Lei Sun;Matthew Bogyo

  • The ER-luminal domain of the HCMV glycoprotein US6 inhibits peptide translocation by TAP.

    Kwangseog Ahn;Albrecht Gruhler;Begona Galocha;Thomas R Jones

  • Human cytomegalovirus US3 impairs transport and maturation of major histocompatibility complex class I heavy chains

    Thomas R. Jones;Emmanuel J. H. J. Wiertz;Lei Sun;Kenneth N. Fish

  • Human HRD1 is an E3 ubiquitin ligase involved in degradation of proteins from the endoplasmic reticulum.

    Marjolein Kikkert;Ram Doolman;Min Dai;Rachel Avner

  • Recruitment of the p97 ATPase and ubiquitin ligases to the site of retrotranslocation at the endoplasmic reticulum membrane

    Yihong Ye;Yoko Shibata;Marjolein Kikkert;Sjaak van Voorden

  • Ubiquitination of serine, threonine, or lysine residues on the cytoplasmic tail can induce ERAD of MHC-I by viral E3 ligase mK3.

    Xiaoli Wang;Roger A. Herr;Wei Jen Chua;Lonnie Lybarger

  • Viral immune evasion: a masterpiece of evolution.

    Mireille T M Vossen;Ellen M Westerhout;Cécilia Söderberg-Nauclér;Emmanuel J H J Wiertz

  • CRISPR/Cas9-Mediated Genome Editing of Herpesviruses Limits Productive and Latent Infections.

    Ferdy R. van Diemen;Elisabeth M. Kruse;Marjolein J. G. Hooykaas;Carlijn E. Bruggeling

  • Host shutoff during productive Epstein-Barr virus infection is mediated by BGLF5 and may contribute to immune evasion.

    Martin Rowe;Britt Glaunsinger;Daphne van Leeuwen;Jianmin Zuo

  • The ubiquitin-domain protein HERP forms a complex with components of the endoplasmic reticulum associated degradation pathway.

    Andrea Schulze;Sybille Standera;Elke Buerger;Marjolein Kikkert

  • Varicelloviruses avoid T cell recognition by UL49.5-mediated inactivation of the transporter associated with antigen processing

    Danijela Koppers-Lalic;Eric A. J. Reits;Maaike E. Ressing;Andrea D. Lipinska

  • The Epstein-Barr Virus G-Protein-Coupled Receptor Contributes to Immune Evasion by Targeting MHC Class I Molecules for Degradation

    Jianmin Zuo;Andrew Currin;Bryan D. Griffin;Claire Shannon-Lowe

  • A CD8+ T cell immune evasion protein specific to Epstein-Barr virus and its close relatives in Old World primates.

    Andrew D. Hislop;Maaike E. Ressing;Daphne van Leeuwen;Victoria A. Pudney

  • TEB4 is a C4HC3 RING finger-containing ubiquitin ligase of the endoplasmic reticulum.

    Gerco Hassink;Marjolein Kikkert;Sjaak Van Voorden;Shiow Ju Lee

  • Biosafety assessment of probiotics used for human consumption: recommendations from the EU-PROSAFE project

    Vanessa Vankerckhoven;Vanessa Vankerckhoven;Geert Huys;Marc Vancanneyt;Carl Vael

  • The HCMV Gene Products US11 and US2 Differ in Their Ability to Attack Allelic Forms of Murine Major Histocompatibility Complex (MHC) Class I Heavy Chains

    Robert P. Machold;Emmanuel J.H.J. Wiertz;Thomas R. Jones;H.L. Ploegh

  • Immune evasion by human cytomegalovirus: lessons in immunology and cell biology

    Wil A.M Loenen;C.A Bruggeman;E.J.H.J Wiertz

  • The TRC8 E3 ligase ubiquitinates MHC class I molecules before dislocation from the ER

    Helen R. Stagg;Mair Thomas;Dick van den Boomen;Emmanuel J.H.J. Wiertz

  • Epstein-Barr virus evasion of CD8(+) and CD4(+) T cell immunity via concerted actions of multiple gene products.

    Maaike E. Ressing;Daniëlle Horst;Bryan D. Griffin;Judy Tellam

  • Herpesviruses and immunity: the art of evasion.

    Bryan D. Griffin;Marieke C. Verweij;Emmanuel J.H.J. Wiertz;Emmanuel J.H.J. Wiertz

Frequent Co-Authors

Rob C. Hoeben
Rob C. Hoeben Leiden University Medical Center
Hidde L. Ploegh
Hidde L. Ploegh Boston Children's Hospital
Jacques Neefjes
Jacques Neefjes Leiden University Medical Center
Arend Mulder
Arend Mulder Leiden University Medical Center
Bart O. Roep
Bart O. Roep Leiden University Medical Center
Ted H. Hansen
Ted H. Hansen Washington University in St. Louis
Elisabeth Kremmer
Elisabeth Kremmer Max Planck Society
Martin Rowe
Martin Rowe University of Birmingham
Robert Tampé
Robert Tampé Goethe University Frankfurt
Klaus Früh
Klaus Früh Oregon Health & Science University

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