World's Best Scientists 2026 revealed!
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Biology and Biochemistry
Netherlands
2025

D-Index & Metrics

Immunology

D-Index
116
Citations
47792
World Ranking
379
National Ranking
14

Jacques Neefjes publication distribution in Immunology in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Immunology in 2026. The highlighted bar marks where Jacques Neefjes sits on this spectrum.

62–71 publications: 9 scientists 72–81 publications: 23 scientists 82–91 publications: 40 scientists 92–101 publications: 72 scientists 102–111 publications: 86 scientists 112–121 publications: 108 scientists 122–131 publications: 150 scientists 132–141 publications: 160 scientists 142–151 publications: 159 scientists 152–161 publications: 189 scientists 162–171 publications: 166 scientists 172–181 publications: 181 scientists 182–191 publications: 188 scientists 192–201 publications: 187 scientists 202–211 publications: 178 scientists 212–221 publications: 158 scientists 222–231 publications: 168 scientists 232–241 publications: 159 scientists 242–251 publications: 160 scientists 252–261 publications: 148 scientists 262–271 publications: 116 scientists 272–281 publications: 125 scientists 282–291 publications: 115 scientists 292–301 publications: 111 scientists 302–311 publications: 95 scientists 312–321 publications: 97 scientists 322–331 publications: 97 scientists 332–341 publications: 99 scientists 342–351 publications: 96 scientists 352–361 publications: 69 scientists 362–371 publications: 76 scientists 372–381 publications: 71 scientists 382–391 publications: 71 scientists 392–401 publications: 62 scientists 402–411 publications: 54 scientists 412–421 publications: 41 scientists 422–431 publications: 63 scientists 432–441 publications: 53 scientists 442–451 publications: 31 scientists 452–461 publications: 42 scientists 462–471 publications: 40 scientists 472–481 publications: 29 scientists 482–491 publications: 34 scientists 492–501 publications: 30 scientists 502–511 publications: 23 scientists 512–521 publications: 41 scientists 522–531 publications: 29 scientists 532–541 publications: 28 scientists 542–551 publications: 16 scientists 552–561 publications: 18 scientists 562–571 publications: 18 scientists 572–581 publications: 17 scientists 582–591 publications: 17 scientists 592–601 publications: 17 scientists 602–611 publications: 19 scientists 612–621 publications: 13 scientists 622–631 publications: 12 scientists 632–641 publications: 11 scientists 642–651 publications: 16 scientists 652–661 publications: 9 scientists 662–671 publications: 5 scientists 672–681 publications: 13 scientists 682–691 publications: 12 scientists 692–701 publications: 6 scientists 702–711 publications: 6 scientists 712–721 publications: 9 scientists 722–731 publications: 9 scientists 732–741 publications: 6 scientists 742–751 publications: 11 scientists 752–761 publications: 10 scientists 762–771 publications: 7 scientists 772–781 publications: 12 scientists 782–791 publications: 7 scientists 792–801 publications: 5 scientists 802–806 publications: 1 scientists 807+ publications: 100 scientists
62 publications 807+

This scientist: 368 publications — 76th percentile

76% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 807 publications or more.

Jacques Neefjes D-index placement in Immunology in 2026

The chart shows the D-index (discipline H-index) distribution of Immunology scientists ranked by Research.com in 2026. The highlighted bar marks where Jacques Neefjes sits on this spectrum.

40–41 D-Index: 28 scientists 42–43 D-Index: 91 scientists 44–45 D-Index: 157 scientists 46–47 D-Index: 192 scientists 48–49 D-Index: 175 scientists 50–51 D-Index: 188 scientists 52–53 D-Index: 177 scientists 54–55 D-Index: 155 scientists 56–57 D-Index: 194 scientists 58–59 D-Index: 201 scientists 60–61 D-Index: 197 scientists 62–63 D-Index: 201 scientists 64–65 D-Index: 173 scientists 66–67 D-Index: 167 scientists 68–69 D-Index: 172 scientists 70–71 D-Index: 199 scientists 72–73 D-Index: 184 scientists 74–75 D-Index: 133 scientists 76–77 D-Index: 163 scientists 78–79 D-Index: 127 scientists 80–81 D-Index: 121 scientists 82–83 D-Index: 125 scientists 84–85 D-Index: 121 scientists 86–87 D-Index: 102 scientists 88–89 D-Index: 96 scientists 90–91 D-Index: 75 scientists 92–93 D-Index: 72 scientists 94–95 D-Index: 74 scientists 96–97 D-Index: 66 scientists 98–99 D-Index: 68 scientists 100–101 D-Index: 49 scientists 102–103 D-Index: 60 scientists 104–105 D-Index: 54 scientists 106–107 D-Index: 36 scientists 108–109 D-Index: 23 scientists 110–111 D-Index: 52 scientists 112–113 D-Index: 41 scientists 114–115 D-Index: 34 scientists 116–117 D-Index: 25 scientists 118–119 D-Index: 28 scientists 120–121 D-Index: 11 scientists 122–123 D-Index: 20 scientists 124–125 D-Index: 27 scientists 126–127 D-Index: 19 scientists 128–129 D-Index: 20 scientists 130–131 D-Index: 16 scientists 132–133 D-Index: 17 scientists 134–135 D-Index: 14 scientists 136–137 D-Index: 15 scientists 138–139 D-Index: 9 scientists 140–141 D-Index: 11 scientists 142–143 D-Index: 9 scientists 144–145 D-Index: 9 scientists 146–147 D-Index: 7 scientists 148–149 D-Index: 7 scientists 150–151 D-Index: 7 scientists 152–153 D-Index: 5 scientists 154–155 D-Index: 8 scientists 156 D-Index: 6 scientists 157+ D-Index: 96 scientists
40 D-Index 157+

This scientist: 116 D-Index — 93rd percentile

93% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 157 D-Index or more.

Research.com Recognitions

  • 2025 - Research.com Biology and Biochemistry in Netherlands Leader Award
  • 2023 - Research.com Biology and Biochemistry in Netherlands Leader Award
  • 2022 - Research.com Biology and Biochemistry in Netherlands Leader Award
  • 2015 - Royal Netherlands Academy of Arts and Sciences
  • 2013 - Member of Academia Europaea
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Jacques Neefjes is affiliated with Leiden University Medical Center in the Netherlands. Their research spans multiple domains within life sciences, with a primary focus on biochemistry, genetics, and molecular biology, complemented by contributions to medicine and immunology and microbiology.

Their subfields of study include molecular biology, immunology, oncology, cell biology, and physiology. The main scientific topics of their work cover immune cell function and interaction, immunotherapy and immune responses, cellular transport and secretion, T-cell and B-cell immunology, cancer therapeutics and mechanisms, cancer treatment and pharmacology, as well as calcium signaling and nucleotide metabolism.

Jacques Neefjes has published extensively, with a notable presence in frequent publication venues such as bioRxiv (Cold Spring Harbor Laboratory), Cell Reports, Journal of Cell Science, Molecular Immunology, and iScience.

Recent papers by Neefjes include:

  • New insights into the activities and toxicities of the old anticancer drug doxorubicin, 2020, FEBS Journal
  • Uncoupling DNA damage from chromatin damage to detoxify doxorubicin, 2020, Proceedings of the National Academy of Sciences
  • The SPPL3-Defined Glycosphingolipid Repertoire Orchestrates HLA Class I-Mediated Immune Responses, 2020, Immunity
  • Opportunities for Small Molecules in Cancer Immunotherapy, 2020, Trends in Immunology
  • SKIP - HOPS recruits TBC 1D15 for a Rab7-to-Arl8b identity switch to control late endosome transport, 2020, The EMBO Journal

Collaboration has been an important aspect of Neefjes' work, with frequent co-authors including Sabina Y. van der Zanden, Birol Cabukusta, Jimmy J.L.L. Akkermans, Marlieke L.M. Jongsma, and Ilana Berlin. These partnerships have contributed to a substantial and diverse body of research.

Neefjes has received recognition in the scientific community, including being named a member of the Royal Netherlands Academy of Arts and Sciences in 2015, membership in Academia Europaea in 2013, and election to the European Molecular Biology Organization (EMBO).

Best Publications

  • Towards a systems understanding of MHC class I and MHC class II antigen presentation

    Jacques Neefjes;Marlieke L. M. Jongsma;Petra Paul;Oddmund Bakke

  • Radiation modulates the peptide repertoire, enhances MHC class I expression, and induces successful antitumor immunotherapy

    Eric A. Reits;James W Hodge;Carla A Herberts;Tom A M Groothuis

  • Empty MHC class I molecules come out in the cold

    H G Ljunggren;N J Stam;C Ohlén;J J Neefjes

  • The Rab7 effector protein RILP controls lysosomal transport by inducing the recruitment of dynein-dynactin motors

    Ingrid Jordens;Mar Fernandez-Borja;Marije Marsman;Simone Dusseljee

  • From fixed to FRAP: measuring protein mobility and activity in living cells.

    Eric A.J. Reits;Jacques J. Neefjes

  • Segregation of MHC class II molecules from MHC class I molecules in the Golgi complex for transport to lysosomal compartments.

    Peter J. Peters;Jacques J. Neefjes;Viola Oorschot;Hidde L. Ploegh

  • Present Yourself! By MHC Class I and MHC Class II Molecules

    Kenneth L. Rock;Eric Reits;Jacques Neefjes;Jacques Neefjes

  • Cholesterol sensor ORP1L contacts the ER protein VAP to control Rab7-RILP-p150 Glued and late endosome positioning

    Nuno Rocha;Coenraad Kuijl;Rik van der Kant;Lennert Janssen

  • Interference with HIV-induced syncytium formation and viral infectivity by inhibitors of trimming glucosidase.

    Rob A. Gruters;Jacques J. Neefjes;Matthijs Tersmette;Ruud E. Y. de Goede

  • Selective and ATP-dependent translocation of peptides by the MHC-encoded transporter

    Jacques J. Neefjes;Frank Momburg;Günter J. Hämmerling

  • E-selectin and intercellular adhesion molecule-1 are released by activated human endothelial cells in vitro.

    J. F. M. Leeuwenberg;E. F. Smeets;J. J. Neefjes;M. A. Shaffer

  • Making sense of mass destruction: quantitating MHC class I antigen presentation.

    Jonathan W. Yewdell;Eric Reits;Jacques Neefjes

  • Activation of endosomal dynein motors by stepwise assembly of Rab7–RILP–p150Glued, ORP1L, and the receptor βlll spectrin

    Marie Johansson;Nuno Rocha;Wilbert Zwart;Ingrid Jordens

  • The biosynthetic pathway of MHC class II but not class I molecules intersects the endocytic route.

    Jacques J. Neefjes;Volker Stollorz;Peter J. Peters;Hans J. Geuze

  • Cross-presentation by intercellular peptide transfer through gap junctions

    Joost Neijssen;Carla Herberts;Jan Wouter Drijfhout;Eric Reits

  • The major substrates for TAP in vivo are derived from newly synthesized proteins

    Eric A. J. Reits;Jan C. Vos;Monique Grommé;Jacques Neefjes

  • Direct binding of peptide to empty MHC class I molecules on intact cells and in vitro

    Ton N.M. Schumacher;Marie-Thérèse Heemels;Jacques J. Neefjes;W.Martin Kast

  • MED12 Controls the Response to Multiple Cancer Drugs through Regulation of TGF-β Receptor Signaling.

    Sidong Huang;Michael Hölzel;Theo Knijnenburg;Andreas Schlicker

  • Drug-induced histone eviction from open chromatin contributes to the chemotherapeutic effects of doxorubicin

    Baoxu Pang;Xiaohang Qiao;Lennert Janssen;Arno Velds

  • Mice lacking the MHC class II-associated invariant chain

    Stéphane Viville;Stéphane Viville;Jacques Neefjes;Vincent Lotteau;Andrée Dierich;Andrée Dierich

  • MANNOSE RECEPTOR-MEDIATED UPTAKE OF ANTIGENS STRONGLY ENHANCES HLA CLASS II-RESTRICTED ANTIGEN PRESENTATION BY CULTURED DENDRITIC CELLS

    M. C. A. A. Tan;A. M. Mommaas;J. W. Drijfhout;R. Jordens

Frequent Co-Authors

Hans Janssen
Hans Janssen KU Leuven
Hidde L. Ploegh
Hidde L. Ploegh Boston Children's Hospital
Huib Ovaa
Huib Ovaa Leiden University Medical Center
Frank Momburg
Frank Momburg German Cancer Research Center
Jero Calafat
Jero Calafat Antoni van Leeuwenhoek Hospital
Günter J. Hämmerling
Günter J. Hämmerling German Cancer Research Center
Jannie Borst
Jannie Borst Leiden University Medical Center
Thijn R. Brummelkamp
Thijn R. Brummelkamp Antoni van Leeuwenhoek Hospital
Peter A. van Veelen
Peter A. van Veelen Leiden University Medical Center
Jan W. Drijfhout
Jan W. Drijfhout Leiden University Medical Center

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