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Biology and Biochemistry

D-Index
69
Citations
18525
World Ranking
7330
National Ranking
189

Overview

Peter A. van Veelen is affiliated with Leiden University Medical Center in the Netherlands. Their research spans several main fields including Biochemistry, Genetics and Molecular Biology, Medicine, and Immunology and Microbiology. Within these areas, their work concentrates notably on subfields such as Molecular Biology, Immunology, Oncology, Radiology, Nuclear Medicine and Imaging, and Genetics.

Their publication record highlights multiple main topics of research interest. These include:

  • Immunotherapy and Immune Responses
  • Monoclonal and Polyclonal Antibodies Research
  • T-cell and B-cell Immunology
  • Glycosylation and Glycoproteins Research
  • Immune Cell Function and Interaction
  • Peptidase Inhibition and Analysis
  • CAR-T cell therapy research

Peter A. van Veelen has authored papers in a range of scientific journals and venues, with the most frequent publication outlets including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Blood
  • Cell Reports
  • Frontiers in Immunology
  • Annals of the Rheumatic Diseases

Notable recent publications include:

  • PHGDH heterogeneity potentiates cancer cell dissemination and metastasis (2022, Nature)
  • Antibodies and B cells recognising citrullinated proteins display a broad cross-reactivity towards other post-translational modifications (2020, Annals of the Rheumatic Diseases)
  • Human VAPome Analysis Reveals MOSPD1 and MOSPD3 as Membrane Contact Site Proteins Interacting with FFAT-Related FFNT Motifs (2020, Cell Reports)
  • Small-Molecule Activity-Based Probe for Monitoring Ubiquitin C-Terminal Hydrolase L1 (UCHL1) Activity in Live Cells and Zebrafish Embryos (2020, Journal of the American Chemical Society)
  • Exploring the Versatility of the Covalent Thiol-Alkyne Reaction with Substituted Propargyl Warheads: A Deciding Role for the Cysteine Protease (2021, Journal of the American Chemical Society)

Frequent collaborators in their research career include:

  • Arnoud H. de Ru
  • George M. C. Janssen
  • Rayman T.N. Tjokrodirijo
  • Paul J. Hensbergen
  • Mirjam H.M. Heemskerk

Best Publications

  • Radiation modulates the peptide repertoire, enhances MHC class I expression, and induces successful antitumor immunotherapy

    Eric A. Reits;James W Hodge;Carla A Herberts;Tom A M Groothuis

  • Alpha-gliadin genes from the A, B, and D genomes of wheat contain different sets of celiac disease epitopes

    Teun W J M van Herpen;Svetlana V Goryunova;Svetlana V Goryunova;Johanna van der Schoot;Makedonka Mitreva;Makedonka Mitreva

  • Autoantibodies recognizing carbamylated proteins are present in sera of patients with rheumatoid arthritis and predict joint damage

    Jing Shi;Rachel Knevel;Parawee Suwannalai;Michael P. van der Linden

  • The gluten response in children with celiac disease is directed toward multiple gliadin and glutenin peptides

    Willemijn Vader;Yvonne Kooy;Peter van Veelen;Arnoud de Ru

  • Specificity of Tissue Transglutaminase Explains Cereal Toxicity in Celiac Disease

    L. Willemijn Vader;Arnoud de Ru;Yvonne van der Wal;Yvonne M.C. Kooy

  • Highly efficient gluten degradation with a newly identified prolyl endoprotease: implications for celiac disease

    Dariusz Stepniak;Liesbeth Spaenij-Dekking;Cristina Mitea;Martine Moester

  • Thrombocidins, Microbicidal Proteins from Human Blood Platelets, Are C-terminal Deletion Products of CXC Chemokines

    J. Krijgsveld;S.A.J. Zaat;J. Meeldijk;P.A. van Veelen

  • Peptide diffusion, protection, and degradation in nuclear and cytoplasmic compartments before antigen presentation by MHC class I.

    Eric Reits;Alexander Griekspoor;Joost Neijssen;Tom Groothuis

  • Efficient Identification of Novel HLA-A * 0201-presented Cytotoxic T Lymphocyte Epitopes in the Widely Expressed Tumor Antigen PRAME by Proteasome-mediated Digestion Analysis

    Jan H. Kessler;Nico J. Beekman;Sandra A. Bres-Vloemans;Pauline Verdijk

  • Autoreactive CD8 T cells associated with β cell destruction in type 1 diabetes

    Gabrielle G. M. Pinkse;Odette H. M. Tysma;Cees A. M. Bergen;Michel G. D. Kester

  • Characterization of cereal toxicity for celiac disease patients based on protein homology in grains.

    L.Willemijn Vader;Dariusz T Stepniak;Evelien M Bunnik;Yvonne M.C Kooy

  • Natural Variation in Toxicity of Wheat: Potential for Selection of Nontoxic Varieties for Celiac Disease Patients

    Liesbeth Spaenij–Dekking;Yvonne Kooy–Winkelaar;Peter van Veelen;Jan Wouter Drijfhout

  • Small intestinal T cells of celiac disease patients recognize a natural pepsin fragment of gliadin

    Yvonne van de Wal;Yvonne M. C. Kooy;Peter A. van Veelen;Salvador A. Peña

  • Efficient −2 frameshifting by mammalian ribosomes to synthesize an additional arterivirus protein

    Ying Fang;Emmely E. Treffers;Yanhua Li;Ali Tas

  • Glutenin is involved in the gluten-driven mucosal T cell response.

    Yvonne van de Wal;Yvonne M. C. Kooy;Peter van Veelen;Willemijn Vader

  • Dendritic cells process synthetic long peptides better than whole protein, improving antigen presentation and T-cell activation.

    Rodney A. Rosalia;Esther D. Quakkelaar;Anke Redeker;Selina Khan

  • Cytomegalovirus in autoimmunity: T cell crossreactivity to viral antigen and autoantigen glutamic acid decarboxylase

    Hoebert S. Hiemstra;Nanette C. Schloot;Peter A. van Veelen;Sabine J. M. Willemen

  • Autoimmunity against a defective ribosomal insulin gene product in type 1 diabetes

    Maria J L Kracht;Menno van Lummel;Tatjana Nikolic;Antoinette M Joosten

  • An ER-Associated Pathway Defines Endosomal Architecture for Controlled Cargo Transport

    Marlieke L.M. Jongsma;Ilana Berlin;Ruud H.M. Wijdeven;Lennert Janssen

  • Cutting Edge: Selective Deamidation by Tissue Transglutaminase Strongly Enhances Gliadin-Specific T Cell

    Yvonne van de Wal;Yvonne Kooy;Peter van Veelen;Luisa Mearin

Frequent Co-Authors

Jan W. Drijfhout
Jan W. Drijfhout Leiden University Medical Center
Frits Koning
Frits Koning Leiden University Medical Center
J.H. Frederik Falkenburg
J.H. Frederik Falkenburg Leiden University Medical Center
Mirjam H.M. Heemskerk
Mirjam H.M. Heemskerk Leiden University Medical Center
Bart O. Roep
Bart O. Roep Leiden University Medical Center
Ferry Ossendorp
Ferry Ossendorp Leiden University Medical Center
René E. M. Toes
René E. M. Toes Leiden University Medical Center
Manfred Wuhrer
Manfred Wuhrer Leiden University Medical Center
Jacques Neefjes
Jacques Neefjes Leiden University Medical Center
Huib Ovaa
Huib Ovaa Leiden University Medical Center

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