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Medicine

D-Index
103
Citations
33323
World Ranking
7439
National Ranking
285

Overview

Tom W. J. Huizinga is affiliated with Leiden University Medical Center in the Netherlands. Their research primarily focuses on medicine, with a significant contribution to the field of rheumatology.

The scientist's work spans multiple subfields of study, including:

  • Rheumatology
  • Pathology and Forensic Medicine
  • Immunology
  • Radiology, Nuclear Medicine and Imaging
  • Genetics

The main topics covered in their research include:

  • Systemic Lupus Erythematosus Research
  • Rheumatoid Arthritis Research and Therapies
  • Monoclonal and Polyclonal Antibodies Research
  • Systemic Sclerosis and Related Diseases
  • Chronic Lymphocytic Leukemia Research
  • Lymphoma Diagnosis and Treatment
  • Autoimmune and Inflammatory Disorders Research

Tom W. J. Huizinga has published extensively in various scientific venues, with frequent publications in:

  • Annals of the Rheumatic Diseases
  • RMD Open
  • Lara D. Veeken
  • Arthritis Research & Therapy
  • Arthritis & Rheumatology

The scientist often collaborates with other researchers. Frequent co-authors include:

  • René E. M. Toes (50 joint publications)
  • Cornelia F Allaart (33 joint publications)
  • Sytske Anne Bergstra (25 joint publications)
  • Jeska K de Vries-Bouwstra (24 joint publications)
  • Hans Ulrich Scherer (23 joint publications)

Some of their recent papers highlight ongoing research endeavors and include the following:

  • EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2019 update, 2020, Annals of the Rheumatic Diseases
  • An overview of autoantibodies in rheumatoid arthritis, 2020, Journal of Autoimmunity
  • Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis, 2022, Nature Genetics
  • Intervention with methotrexate in patients with arthralgia at risk of rheumatoid arthritis to reduce the development of persistent arthritis and its disease burden (TREAT EARLIER): a randomised, double-blind, placebo-controlled, proof-of-concept trial, 2022, The Lancet
  • Abatacept in individuals at high risk of rheumatoid arthritis (APIPPRA): a randomised, double-blind, multicentre, parallel, placebo-controlled, phase 2b clinical trial, 2024, The Lancet

Best Publications

  • Association between weight or Body Mass Index and hand osteoarthritis: a systematic review

    Erlangga Yusuf;Rob G Nelissen;Andreea Ioan-Facsinay;Vedrana Stojanovic-Susulic

  • Association between HLA class II genes and autoantibodies to cyclic citrullinated peptides (CCPs) influences the severity of rheumatoid Arthritis

    Floris A van Gaalen;Jill van Aken;Tom W J Huizinga;Geziena M Th Schreuder

  • Long-Term Impact of Delay in Assessment of Patients With Early Arthritis

    Michael P. M. van der Linden;Saskia le Cessie;Karim Raza;Diane van der Woude

  • The HLA-DRB1 shared epitope alleles are primarily a risk factor for anti-cyclic citrullinated peptide antibodies and are not an independent risk factor for development of rheumatoid arthritis.

    Annette H M van der Helm-van Mil;Kirsten N Verpoort;Ferdinand C Breedveld;Tom W J Huizinga

  • Identification of PLOD2 as Telopeptide Lysyl Hydroxylase, an Important Enzyme in Fibrosis

    Annemarie J. van der Slot;Anne-Marie Zuurmond;Alfons F.J. Bardoel;Cisca Wijmenga

  • Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci

    Alexandra Zhernakova;Alexandra Zhernakova;Alexandra Zhernakova;Eli A. Stahl;Eli A. Stahl;Gosia Trynka;Soumya Raychaudhuri

  • Do knee abnormalities visualised on MRI explain knee pain in knee osteoarthritis? A systematic review

    Erlangga Yusuf;Marion C Kortekaas;Iain Watt;Tom W J Huizinga

  • A genetic study on C5-TRAF1 and progression of joint damage in rheumatoid arthritis

    Hanna W. van Steenbergen;Luis Rodríguez-Rodríguez;Ewa Berglin;Alexandra Zhernakova

  • Defining conditions where long-term glucocorticoid treatment has an acceptably low level of harm to facilitate implementation of existing recommendations: viewpoints from an EULAR task force

    Cindy Strehl;Johannes W J Bijlsma;Maarten de Wit;Maarten Boers

  • Quantitative heritability of anti-citrullinated protein antibody-positive and anti-citrullinated protein antibody-negative rheumatoid arthritis.

    Diane van der Woude;Jeanine J. Houwing-Duistermaat;René E. M. Toes;Tom W. J. Huizinga

  • The 2010 American College of Rheumatology/European League Against Rheumatism classification criteria for rheumatoid arthritis: Methodological Report Phase I

    Julia Funovits;Daniel Aletaha;Vivian Bykerk;Bernard Combe

  • Classification of rheumatoid arthritis: Comparison of the 1987 American College of Rheumatology criteria and the 2010 American College of Rheumatology/European League Against Rheumatism criteria

    M. P. M. van der Linden;R. Knevel;T. W. J. Huizinga;A. H. M van der Helm-van Mil

  • Rheumatoid arthritis is a heterogeneous disease - Evidence for differences in the activation of the STAT-1 pathway between rheumatoid tissues

    Tineke C. T. M. van der Pouw Kraan;Floris A. van Gaalen;Pia V. Kasperkovitz;Nicolette L. Verbeet

  • Extended report: Evidence for treating rheumatoid arthritis to target: results of a systematic literature search

    Monika Schoels;Rachel Knevel;Daniel Aletaha;Johannes W J Bijlsma

  • A clinical pharmacogenetic model to predict the efficacy of methotrexate monotherapy in recent-onset rheumatoid arthritis.

    Judith A. M. Wessels;Sjoerd M. van der Kooij;Saskia le Cessie;Wietske Kievit

  • Efficacy and toxicity of methotrexate in early rheumatoid arthritis are associated with single‐nucleotide polymorphisms in genes coding for folate pathway enzymes

    Judith A. M. Wessels;Jeska K. de Vries-Bouwstra;Bas T. Heijmans;P. Eline Slagboom

  • Antibodies to Porphyromonas gingivalis Are Associated with Anticitrullinated Protein Antibodies in Patients with Rheumatoid Arthritis and Their Relatives

    Carol A Hitchon;Fatiha Chandad;Elizabeth D Ferucci;Annemiek Willemze

  • Evaluating drug-free remission with abatacept in early rheumatoid arthritis: results from the phase 3b, multicentre, randomised, active-controlled AVERT study of 24 months, with a 12-month, double-blind treatment period

    Paul Emery;Gerd R Burmester;Vivian P Bykerk;Bernard G Combe

  • An overview of autoantibodies in rheumatoid arthritis

    Myrthe A.M. van Delft;Tom W.J. Huizinga

  • Prevalence of and predictive factors for sustained disease-modifying antirheumatic drug-free remission in rheumatoid arthritis: results from two large early arthritis cohorts.

    Diane van der Woude;Adam Young;Keeranur Jayakumar;Bart J. Mertens

Frequent Co-Authors

René E. M. Toes
René E. M. Toes Leiden University Medical Center
Peter A. Nigrovic
Peter A. Nigrovic Boston Children's Hospital
Leendert A. Trouw
Leendert A. Trouw Leiden University Medical Center
Désirée van der Heijde
Désirée van der Heijde Leiden University Medical Center
Ferdinand C. Breedveld
Ferdinand C. Breedveld Leiden University Medical Center
Lars Klareskog
Lars Klareskog Karolinska Institute
Peter K. Gregersen
Peter K. Gregersen Feinstein Institute for Medical Research
Robert M. Plenge
Robert M. Plenge Bristol Myers Squibb
Soumya Raychaudhuri
Soumya Raychaudhuri Brigham and Women's Hospital
Paul P. Tak
Paul P. Tak GlaxoSmithKline (United Kingdom)

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